Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

(2014) Hiroaki Hirata et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Actomyosin-dependent formation of the mechanosensitive talin–vinculin complex reinforces actin anchoring

(2014) Corina Ciobanasu et al.   Nature Communications

Talin Autoinhibition Is Required for Morphogenesis

(2013) Stephanie J. Ellis et al.   CURRENT BIOLOGY

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

(2013) Benjamin T. Goult et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation

(2013) Benjamin T. Goult et al.   JOURNAL OF STRUCTURAL BIOLOGY

Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function

(2013) Hu Chen et al.   Scientific Reports

Subcellular Localization of Talin Is Regulated by Inter-domain Interactions

(2012) Asoka Banno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation

(2012) Tzu-Wei Chuang et al.   MOLECULAR BIOLOGY OF THE CELL

Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages

(2012) Y. Gao et al.   SCIENCE

Improved High-Force Magnetic Tweezers for Stretching and Refolding of Proteins and Short DNA

(2011) Hu Chen et al.   BIOPHYSICAL JOURNAL

Differential Mechanical Stability of Filamin A Rod Segments

(2011) Hu Chen et al.   BIOPHYSICAL JOURNAL

Mechanotransduction In Vivo by Repeated Talin Stretch-Relaxation Events Depends upon Vinculin

(2011) Felix Margadant et al.   PLOS BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching

(2010) Hongxia Fu et al.   NUCLEIC ACIDS RESEARCH

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

(2010) Paul R. Elliott et al.   STRUCTURE

Cell Mechanics: Dissecting the Physical Responses of Cells to Force

(2009) Brenton D. Hoffman et al.   Annual Review of Biomedical Engineering

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

Podosomes are present in a postsynaptic apparatus and participate in its maturation

(2009) T. J. Proszynski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences

(2008) Ho-Sup Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Autoinhibition of Talin in Regulating Integrin Activation

(2008) Esen Goksoy et al.   MOLECULAR CELL

How Force Might Activate Talin's Vinculin Binding Sites: SMD Reveals a Structural Mechanism

(2008) Vesa P. Hytönen et al.   PLoS Computational Biology