Adherens Junction and E-Cadherin complex regulation by epithelial polarity

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

(2015) Tao Jiang et al.   CURRENT BIOLOGY

Drosophila MAGI interacts with RASSF8 to regulate E-Cadherin-based adherens junctions in the developing eye

(2015) S. Zaessinger et al.   DEVELOPMENT

Allosteric Regulation of E-Cadherin Adhesion

(2015) Nitesh Shashikanth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism

(2015) D. J. Escobar et al.   JOURNAL OF CELL SCIENCE

Drosophilap120-catenin is crucial for endocytosis of the dynamic E-cadherin–Bazooka complex

(2015) Natalia A. Bulgakova et al.   JOURNAL OF CELL SCIENCE

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure

(2015) María Elena Fernández-Sánchez et al.   NATURE

E-cadherin junctions as active mechanical integrators in tissue dynamics

(2015) Thomas Lecuit et al.   NATURE CELL BIOLOGY

Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas

(2015) Laurence Veracini et al.   Oncotarget

PI(4,5)P2 Produced by the PI4P5K SKTL Controls Apical Size by Tethering PAR-3 in Drosophila Epithelial Cells

(2014) Sandra Claret et al.   CURRENT BIOLOGY

ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1

(2014) Yihua Wang et al.   NATURE CELL BIOLOGY

CD148 Tyrosine Phosphatase Promotes Cadherin Cell Adhesion

(2014) Keiko Takahashi et al.   PLoS One

The minimal cadherin-catenin complex binds to actin filaments under force

(2014) C. D. Buckley et al.   SCIENCE

Protein Ser/Thr phosphatase-6 is required for maintenance of E-cadherin at adherens junctions

(2013) Takashi Ohama et al.   BMC CELL BIOLOGY

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Septins Regulate the Contractility of the Actomyosin Ring to Enable Adherens Junction Remodeling during Cytokinesis of Epithelial Cells

(2013) Nabila Founounou et al.   DEVELOPMENTAL CELL

PTEN Controls Junction Lengthening and Stability during Cell Rearrangement in Epithelial Tissue

(2013) Pierre-Luc Bardet et al.   DEVELOPMENTAL CELL

Adhesion Disengagement Uncouples Intrinsic and Extrinsic Forces to Drive Cytokinesis in Epithelial Tissues

(2013) Charlène Guillot et al.   DEVELOPMENTAL CELL

Interplay between the Dividing Cell and Its Neighbors Regulates Adherens Junction Formation during Cytokinesis in Epithelial Tissue

(2013) Sophie Herszterg et al.   DEVELOPMENTAL CELL

 -Catenin interacts with APC to regulate  -catenin proteolysis and transcriptional repression of Wnt target genes

(2013) S. H. Choi et al.   GENES & DEVELOPMENT

CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions

(2013) Marta N. Shahbazi et al.   JOURNAL OF CELL BIOLOGY

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

(2013) Simon Hauri et al.   Molecular Systems Biology

Monomeric α-catenin links cadherin to the actin cytoskeleton

(2013) Ridhdhi Desai et al.   NATURE CELL BIOLOGY

Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability

(2013) H Kim et al.   ONCOGENE

p120 catenin is a key effector of a Ras-PKCɛ oncogenic signaling axis

(2013) S G Dann et al.   ONCOGENE

Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis

(2012) Luke Martin McCaffrey et al.   CANCER CELL

Acetylation-Dependent Regulation of Skp2 Function

(2012) Hiroyuki Inuzuka et al.   CELL

A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans

(2012) Allison M. Lynch et al.   CURRENT BIOLOGY

Abl Regulates Planar Polarized Junctional Dynamics through β-Catenin Tyrosine Phosphorylation

(2012) Masako Tamada et al.   DEVELOPMENTAL CELL

Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin

(2012) Gabriela Valls et al.   JOURNAL OF CELL SCIENCE

Assembly of Bazooka polarity landmarks through a multifaceted membrane-association mechanism

(2012) R. F. A. McKinley et al.   JOURNAL OF CELL SCIENCE

Loss of Par3 promotes breast cancer metastasis by compromising cell–cell cohesion

(2012) Bin Xue et al.   NATURE CELL BIOLOGY

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

(2012) Aparna Ratheesh et al.   NATURE CELL BIOLOGY

Reduced Surface Expression of Epithelial E-Cadherin Evoked by Interferon-Gamma Is Fyn Kinase-Dependent

(2012) David Smyth et al.   PLoS One

Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation

(2012) Pavel Krejci et al.   PLoS One

The  -Catenin Destruction Complex

(2012) J. L. Stamos et al.   Cold Spring Harbor Perspectives in Biology

The Apical Polarity Protein Network in Drosophila Epithelial Cells: Regulation of Polarity, Junctions, Morphogenesis, Cell Growth, and Survival

(2011) Ulrich Tepass   Annual Review of Cell and Developmental Biology

Phosphoinositide Binding by Par-3 Involved in Par-3 Localization

(2011) Yosuke Horikoshi et al.   CELL STRUCTURE AND FUNCTION

Epithelial polarity and morphogenesis

(2011) Daniel St Johnston et al.   CURRENT OPINION IN CELL BIOLOGY

Cadherin–actin interactions at adherens junctions

(2011) Shigenobu Yonemura   CURRENT OPINION IN CELL BIOLOGY

Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling

(2011) Buzz Baum et al.   JOURNAL OF CELL BIOLOGY

Wnt controls the transcriptional activity of Kaiso through CK1 -dependent phosphorylation of p120-catenin

(2011) B. del Valle-Perez et al.   JOURNAL OF CELL SCIENCE

Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin

(2011) Andrew L. Smith et al.   MOLECULAR BIOLOGY OF THE CELL

Glycogen Synthase Kinase 3 (GSK-3) influences epithelial barrier function by regulating Occludin, Claudin-1 and E-cadherin expression

(2010) Eric A. Severson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell Polarity in Eggs and Epithelia: Parallels and Diversity

(2010) Daniel St Johnston et al.   CELL

aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells

(2010) Eurico Morais-de-Sá et al.   CELL

ASPP2 Regulates Epithelial Cell Polarity through the PAR Complex

(2010) Weili Cong et al.   CURRENT BIOLOGY

Crumbs/DaPKC-Dependent Apical Exclusion of Bazooka Promotes Photoreceptor Polarity Remodeling

(2010) Rhian F. Walther et al.   CURRENT BIOLOGY

Membrane Targeting of Bazooka/PAR-3 Is Mediated by Direct Binding to Phosphoinositide Lipids

(2010) Michael P. Krahn et al.   CURRENT BIOLOGY

ASPP2 Binds Par-3 and Controls the Polarity and Proliferation of Neural Progenitors during CNS Development

(2010) Roberta Sottocornola et al.   DEVELOPMENTAL CELL

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

(2010) Andrew B. Gladden et al.   DEVELOPMENTAL CELL

Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation

(2010) Sérgio de Matos Simões et al.   DEVELOPMENTAL CELL

Formation of a Bazooka–Stardust complex is essential for plasma membrane polarity in epithelia

(2010) Michael P. Krahn et al.   JOURNAL OF CELL BIOLOGY

Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions

(2010) M. Georgiou et al.   JOURNAL OF CELL SCIENCE

A p120-catenin-CK1  complex regulates Wnt signaling

(2010) D. Casagolda et al.   JOURNAL OF CELL SCIENCE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Drosophila Abelson kinase mediates cell invasion and proliferation through two distinct MAPK pathways

(2010) J Singh et al.   ONCOGENE

The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-κB signaling pathways

(2010) F E Lock et al.   ONCOGENE

The dASPP-dRASSF8 Complex Regulates Cell-Cell Adhesion during Drosophila Retinal Morphogenesis

(2009) Paul F. Langton et al.   CURRENT BIOLOGY

Quantitative analysis of epithelial morphogenesis in Drosophila oogenesis: New insights based on morphometric analysis and mechanical modeling

(2009) K.S. Kolahi et al.   DEVELOPMENTAL BIOLOGY

JNK phosphorylates β-catenin and regulates adherens junctions

(2009) Meng-Horng Lee et al.   FASEB JOURNAL

Protein kinase C-Fyn kinase cascade mediates the oleic acid-induced disassembly of neonatal rat cardiomyocyte adherens junctions

(2009) Kwan-Lih Hsu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Independent cadherin–catenin and Bazooka clusters interact to assemble adherens junctions

(2009) Melanie A. McGill et al.   JOURNAL OF CELL BIOLOGY

Role of the Protein Tyrosine Kinase Syk in Regulating Cell-Cell Adhesion and Motility in Breast Cancer Cells

(2009) X. Zhang et al.   MOLECULAR CANCER RESEARCH

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

(2009) Haitao Ji et al.   MOLECULAR CELL

Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell–cell adhesion

(2009) R M Larive et al.   ONCOGENE

Endocytosis is required for E-cadherin redistribution at mature adherens junctions

(2009) S. de Beco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

(2008) Willem-Jan Pannekoek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

SnapShot: Tight and Adherens Junction Signaling

(2008) Jennifer L. Harder et al.   CELL

Cdc42, Par6, and aPKC Regulate Arp2/3-Mediated Endocytosis to Control Local Adherens Junction Stability

(2008) Marios Georgiou et al.   CURRENT BIOLOGY

Drosophila Cip4 and WASp Define a Branch of the Cdc42-Par6-aPKC Pathway Regulating E-Cadherin Endocytosis

(2008) Andrea Leibfried et al.   CURRENT BIOLOGY

Dual function of Src in the maintenance of adherens junctions during tracheal epithelial morphogenesis

(2008) M. Shindo et al.   DEVELOPMENT

Rho-Kinase Phosphorylates PAR-3 and Disrupts PAR Complex Formation

(2008) Masanori Nakayama et al.   DEVELOPMENTAL CELL

PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCα-dependent pathway

(2008) Meredith V. Brown et al.   EXPERIMENTAL CELL RESEARCH

Par-3-mediated Junctional Localization of the Lipid Phosphatase PTEN Is Required for Cell Polarity Establishment

(2008) Wei Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdc42 and Par proteins stabilize dynamic adherens junctions in theDrosophilaneuroectoderm through regulation of apical endocytosis

(2008) Kathryn P. Harris et al.   JOURNAL OF CELL BIOLOGY

A two-tiered mechanism for stabilization and immobilization of E-cadherin

(2008) Matthieu Cavey et al.   NATURE

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3

(2008) A. Traweger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA