The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms

Formation and disruption of functional domains in myelinated CNS axons

(2017) Ryan B. Griggs et al.   NEUROSCIENCE RESEARCH

Single-Molecule Imaging of Na v 1.6 on the Surface of Hippocampal Neurons Reveals Somatic Nanoclusters

(2016) Elizabeth J. Akin et al.   BIOPHYSICAL JOURNAL

CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability

(2016) Wei-Chun J. Hsu et al.   FASEB JOURNAL

Compromised axon initial segment integrity in EAE is preceded by microglial reactivity and contact

(2016) Kareem C. Clark et al.   GLIA

Polarized localization of voltage-gated Na+channels is regulated by concerted FGF13 and FGF14 action

(2016) Juan Lorenzo Pablo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potassium Channels and Human Epileptic Phenotypes: An Updated Overview

(2016) Chiara Villa et al.   Frontiers in Cellular Neuroscience

Structural and Functional Plasticity at the Axon Initial Segment

(2016) Rei Yamada et al.   Frontiers in Cellular Neuroscience

Voltage-Gated Na+Channels: Not Just for Conduction

(2016) Larisa C. Kruger et al.   Cold Spring Harbor Perspectives in Biology

Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer’s disease mouse model

(2016) V Frazzini et al.   Cell Death & Disease

Location-dependent synaptic plasticity rules by dendritic spine cooperativity

(2016) Jens P. Weber et al.   Nature Communications

Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity

(2016) Steven L. Jones et al.   NEURAL PLASTICITY

Sodium Channel β Subunits: Emerging Targets in Channelopathies

(2015) Heather A. O'Malley et al.   Annual Review of Physiology

Mechanisms of sodium channel clustering and its influence on axonal impulse conduction

(2015) Sean A. Freeman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Subcellular Patterning: Axonal Domains with Specialized Structure and Function

(2015) Elizabeth A. Normand et al.   DEVELOPMENTAL CELL

Amyloid Precursor Protein Enhances Nav1.6 Sodium Channel Cell Surface Expression

(2015) Chao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of stable ER-plasma-membrane junctions by Kv2.1 potassium channels

(2015) P. D. Fox et al.   JOURNAL OF CELL SCIENCE

Activity-dependent regulation of excitable axonal domains

(2015) Keiichiro Susuki et al.   Journal of Physiological Sciences

Trafficking Regulates the Subcellular Distribution of Voltage-Gated Sodium Channels in Primary Sensory Neurons

(2015) Lan Bao   Molecular Pain

Dendritic integration: 60 years of progress

(2015) Greg J Stuart et al.   NATURE NEUROSCIENCE

Modification of tenascin-R expression following unilateral labyrinthectomy in rats indicates its possible role in neural plasticity of the vestibular neural circuit

(2015) Clara Matesz et al.   Neural Regeneration Research

Anti-DPPX encephalitis

(2015) Johannes Piepgras et al.   NEUROLOGY

Subcellular Localization of K+ Channels in Mammalian Brain Neurons: Remarkable Precision in the Midst of Extraordinary Complexity

(2015) James S. Trimmer   NEURON

AMIGO-Kv2.1 Potassium Channel Complex is Associated With Schizophrenia-Related Phenotypes

(2015) Marjaana A. Peltola et al.   SCHIZOPHRENIA BULLETIN

Tuning of Ranvier node and internode properties in myelinated axons to adjust action potential timing

(2015) Marc C. Ford et al.   Nature Communications

Redistribution of Kv1 and Kv7 enhances neuronal excitability during structural axon initial segment plasticity

(2015) Hiroshi Kuba et al.   Nature Communications

Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing

(2015) Mark D. Evans et al.   Cell Reports

A new look at sodium channel   subunits

(2015) S. Namadurai et al.   Open Biology

Dendritic sodium spikes are required for long-term potentiation at distal synapses on hippocampal pyramidal neurons

(2015) Yujin Kim et al.   eLife

Preferential Targeting of Nav1.6 Voltage-Gated Na+ Channels to the Axon Initial Segment during Development

(2015) Elizabeth J. Akin et al.   PLoS One

The node of Ranvier in CNS pathology

(2014) I. Lorena Arancibia-Carcamo et al.   ACTA NEUROPATHOLOGICA

Ankyrin-G Directly Binds to Kinesin-1 to Transport Voltage-Gated Na+ Channels into Axons

(2014) Joshua Barry et al.   DEVELOPMENTAL CELL

Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells

(2014) Tekla Kirizs et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

CK2 accumulation at the axon initial segment depends on sodium channel Nav1

(2014) Y.E. Hien et al.   FEBS LETTERS

Specific Sorting and Post-Golgi Trafficking of Dendritic Potassium Channels in Living Neurons

(2014) Camilla Stampe Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A unique ion channel clustering domain on the axon initial segment of mammalian neurons

(2014) Anna N. King et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Molecular identity of axonal sodium channels in human cortical pyramidal cells

(2014) Cuiping Tian et al.   Frontiers in Cellular Neuroscience

Tenascin-C: Form versus function

(2014) Sean P Giblin et al.   Cell Adhesion & Migration

Saltatory conduction in unmyelinated axons: clustering of Na+ channels on lipid rafts enables micro-saltatory conduction in C-fibers

(2014) Ali Neishabouri et al.   Frontiers in Neuroanatomy

Dendritic Na+ spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons

(2014) Qian Sun et al.   eLife

The anchoring protein SAP97 influences the trafficking and localisation of multiple membrane channels

(2013) Chantelle Fourie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3)

(2013) Alexander S. Shavkunov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionary Analysis of Voltage-Gated Potassium Channels by Bayes Method

(2013) Qi Huang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Microtubules in neurons as information carriers

(2013) Erik W. Dent et al.   JOURNAL OF NEUROCHEMISTRY

KIF5B Promotes the Forward Transport and Axonal Function of the Voltage-Gated Sodium Channel Nav1.8

(2013) Y.-Y. Su et al.   JOURNAL OF NEUROSCIENCE

Regulation of Kv2.1 K+ Conductance by Cell Surface Channel Density

(2013) P. D. Fox et al.   JOURNAL OF NEUROSCIENCE

NaV1.1 Channels in Axon Initial Segments of Bipolar Cells Augment Input to Magnocellular Visual Pathways in the Primate Retina

(2013) T. Puthussery et al.   JOURNAL OF NEUROSCIENCE

Organization and maintenance of molecular domains in myelinated axons

(2013) Elizabeth D. Buttermore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Plasma membrane domains enriched in cortical endoplasmic reticulum function as membrane protein trafficking hubs

(2013) Philip D. Fox et al.   MOLECULAR BIOLOGY OF THE CELL

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Sharpness of Spike Initiation in Neurons Explained by Compartmentalization

(2013) Romain Brette   PLoS Computational Biology

Voltage-Gated Potassium Channels at the Crossroads of Neuronal Function, Ischemic Tolerance, and Neurodegeneration

(2013) Niyathi Hegde Shah et al.   Translational Stroke Research

Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels

(2012) Anna Boronat et al.   ANNALS OF NEUROLOGY

Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segment

(2012) Helene Vacher et al.   EPILEPSIA

Functional maps within a single neuron

(2012) Rishikesh Narayanan et al.   JOURNAL OF NEUROPHYSIOLOGY

An AnkyrinG-Binding Motif Is Necessary and Sufficient for Targeting Nav1.6 Sodium Channels to Axon Initial Segments and Nodes of Ranvier

(2012) A. Gasser et al.   JOURNAL OF NEUROSCIENCE

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

A-type K+channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons

(2012) Yarimar Carrasquillo et al.   JOURNAL OF PHYSIOLOGY-LONDON

Kv4 potassium channels modulate hippocampal EPSP-spike potentiation and spatial memory in rats

(2012) B. Truchet et al.   LEARNING & MEMORY

Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits

(2012) J. N. Lugo et al.   LEARNING & MEMORY

The SNARE complex in neuronal and sensory cells

(2012) Neeliyath A. Ramakrishnan et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Kv2.1 cell surface clusters are insertion platforms for ion channel delivery to the plasma membrane

(2012) Emily Deutsch et al.   MOLECULAR BIOLOGY OF THE CELL

Fusion Pores, SNAREs, and Exocytosis

(2012) Nina Vardjan et al.   NEUROSCIENTIST

Voltage-Gated Sodium Channels: Biophysics, Pharmacology, and Related Channelopathies

(2012) Eleonora Savio-Galimberti et al.   Frontiers in Pharmacology

Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B

(2011) Amandine Duflocq et al.   BMC BIOLOGY

Differential subcellular distribution of ion channels and the diversity of neuronal function

(2011) Zoltan Nusser   CURRENT OPINION IN NEUROBIOLOGY

AMIGO is an auxiliary subunit of the Kv2.1 potassium channel

(2011) Marjaana A Peltola et al.   EMBO REPORTS

The axon initial segment in nervous system disease and injury

(2011) Shelly A. Buffington et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Unique somato-dendritic distribution pattern of Kv4.2 channels on hippocampal CA1 pyramidal cells

(2011) Katalin Kerti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential cycling rates of Kv4.2 channels in proximal and distal dendrites of hippocampal CA1 pyramidal neurons

(2011) Michael W. Nestor et al.   HIPPOCAMPUS

Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting

(2011) Hélène Vacher et al.   JOURNAL OF CELL BIOLOGY

Subunit-Dependent Axonal Trafficking of Distinct   Heteromeric Potassium Channel Complexes

(2011) P. M. Jenkins et al.   JOURNAL OF NEUROSCIENCE

AKAP79/150 Impacts Intrinsic Excitability of Hippocampal Neurons through Phospho-Regulation of A-type K+ Channel Trafficking

(2011) L. Lin et al.   JOURNAL OF NEUROSCIENCE

Short- and Long-Term Plasticity at the Axon Initial Segment

(2011) M. S. Grubb et al.   JOURNAL OF NEUROSCIENCE

Alterations of A-Type Potassium Channels in Hippocampal Neurons after Traumatic Brain Injury

(2011) Zhigang Lei et al.   JOURNAL OF NEUROTRAUMA

Kv1 channels control spike threshold dynamics and spike timing in cortical pyramidal neurones

(2011) Matthew H. Higgs et al.   JOURNAL OF PHYSIOLOGY-LONDON

DPP6 Establishes the A-Type K+ Current Gradient Critical for the Regulation of Dendritic Excitability in CA1 Hippocampal Neurons

(2011) Wei Sun et al.   NEURON

End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment

(2011) C. Leterrier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of voltage-gated ion channels in pyramidal cell dendrites

(2010) S Remy et al.   CURRENT OPINION IN NEUROBIOLOGY

Homophilic Adhesion Mechanism of Neurofascin, a Member of the L1 Family of Neural Cell Adhesion Molecules

(2010) Heli Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier

(2010) Anna Brachet et al.   JOURNAL OF CELL BIOLOGY

Non-conducting function of the Kv2.1 channel enables it to recruit vesicles for release in neuroendocrine and nerve cells

(2010) L. Feinshreiber et al.   JOURNAL OF CELL SCIENCE

Organisation of potassium channels on the neuronal surface

(2010) Rafael Luján   JOURNAL OF CHEMICAL NEUROANATOMY

Kinesin I Transports Tetramerized Kv3 Channels through the Axon Initial Segment via Direct Binding

(2010) M. Xu et al.   JOURNAL OF NEUROSCIENCE

ADAM22, A Kv1 Channel-Interacting Protein, Recruits Membrane-Associated Guanylate Kinases to Juxtaparanodes of Myelinated Axons

(2010) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

NaV1.1 channels and epilepsy

(2010) William A. Catterall et al.   JOURNAL OF PHYSIOLOGY-LONDON

Axon initial segment dysfunction in epilepsy

(2010) Verena C. Wimmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

A Glial Signal Consisting of Gliomedin and NrCAM Clusters Axonal Na+ Channels during the Formation of Nodes of Ranvier

(2010) Konstantin Feinberg et al.   NEURON

Electrophysiology and beyond: Multiple roles of Na+ channel β subunits in development and disease

(2010) Gustavo A. Patino et al.   NEUROSCIENCE LETTERS

Ancillary Subunits Associated With Voltage-Dependent K+ Channels

(2010) Olaf Pongs et al.   PHYSIOLOGICAL REVIEWS

Localization-dependent activity of the Kv2.1 delayed-rectifier K+ channel

(2010) K. M. S. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Identity of Dendritic Voltage-Gated Sodium Channels

(2010) A. Lorincz et al.   SCIENCE

Voltage-gated Potassium Channel as a Facilitator of Exocytosis

(2009) Lori Feinshreiber et al.   Annals of the New York Academy of Sciences

The Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ

(2009) Patrick D Sarmiere et al.   BMC NEUROSCIENCE

Cell-Type-Dependent Molecular Composition of the Axon Initial Segment

(2009) A. Lorincz et al.   JOURNAL OF NEUROSCIENCE

Who let the spikes out?

(2009) Chris G Dulla et al.   NATURE NEUROSCIENCE

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

(2009) Tommy L Lewis et al.   NATURE NEUROSCIENCE

Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation

(2009) Wenqin Hu et al.   NATURE NEUROSCIENCE

Effect of clustered ion channels along an unmyelinated axon

(2009) Shangyou Zeng et al.   PHYSICAL REVIEW E

Kv4.2 is a locus for PKC and ERK/MAPK cross-talk

(2008) Laura A. Schrader et al.   BIOCHEMICAL JOURNAL

The functional organization and assembly of the axon initial segment

(2008) Yasuhiro Ogawa et al.   CURRENT OPINION IN NEUROBIOLOGY

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

(2008) Kristian L. Hedstrom et al.   JOURNAL OF CELL BIOLOGY

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

(2008) Aline Bréchet et al.   JOURNAL OF CELL BIOLOGY

Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus

(2008) Joaquin N. Lugo et al.   JOURNAL OF NEUROCHEMISTRY

Kv4 Accessory Protein DPPX (DPP6) is a Critical Regulator of Membrane Excitability in Hippocampal CA1 Pyramidal Neurons

(2008) Jinhyun Kim et al.   JOURNAL OF NEUROPHYSIOLOGY

Protein Kinase A Mediates Activity-Dependent Kv4.2 Channel Trafficking

(2008) R. S. Hammond et al.   JOURNAL OF NEUROSCIENCE

Dynamic Regulation of the Kv2.1 Voltage-Gated Potassium Channel during Brain Ischemia through Neuroglial Interaction

(2008) H. Misonou et al.   JOURNAL OF NEUROSCIENCE

Interdomain Cytoplasmic Interactions Govern the Intracellular Trafficking, Gating, and Modulation of the Kv2.1 Channel

(2008) D. P. Mohapatra et al.   JOURNAL OF NEUROSCIENCE

Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons

(2008) Jamie Johnston et al.   JOURNAL OF PHYSIOLOGY-LONDON

Functional properties and differential neuromodulation of Nav1.6 channels

(2008) Yuan Chen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments

(2008) Amandine Duflocq et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Compartmentalized dendritic plasticity and input feature storage in neurons

(2008) Attila Losonczy et al.   NATURE

Is action potential threshold lowest in the axon?

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

Plasticity of intrinsic neuronal properties in CNS disorders

(2008) Heinz Beck et al.   NATURE REVIEWS NEUROSCIENCE

Pyramidal neurons: dendritic structure and synaptic integration

(2008) Nelson Spruston   NATURE REVIEWS NEUROSCIENCE

Altered expression of voltage-gated potassium channel 4.2 and voltage-gated potassium channel 4-interacting protein, and changes in intracellular calcium levels following lithium-pilocarpine-induced status epilepticus

(2008) T. Su et al.   NEUROSCIENCE

Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy

(2008) M.M. Monaghan et al.   NEUROSCIENCE

Localization and Targeting of Voltage-Dependent Ion Channels in Mammalian Central Neurons

(2008) Helene Vacher et al.   PHYSIOLOGICAL REVIEWS

The A-Type Potassium Channel Kv4.2 Is a Substrate for the Mitogen-Activated Protein Kinase ERK

(2003) J. Paige Adams et al.   JOURNAL OF NEUROCHEMISTRY