CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability

The Nav1.2 channel is regulated by GSK3

(2015) Thomas F. James et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels

(2015) Mingxuan Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment

(2015) Marie-Jeanne Papandréou et al.   JOURNAL OF NEUROCHEMISTRY

Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism

(2015) Miroslav N. Nenov et al.   JOURNAL OF NEUROPHYSIOLOGY

Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance

(2015) M. K. Bosch et al.   JOURNAL OF NEUROSCIENCE

A Distinct Subtype of Dopaminergic Interneuron Displays Inverted Structural Plasticity at the Axon Initial Segment

(2015) A. N. Chand et al.   JOURNAL OF NEUROSCIENCE

Systematic investigation of hierarchical phosphorylation by protein kinase CK2

(2015) Nicole St-Denis et al.   Journal of Proteomics

Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K+ current inhibition mediated by activation of caspases and GSK-3

(2015) Federico Scala et al.   NEUROBIOLOGY OF AGING

Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27

(2015) Filippo Tempia et al.   Frontiers in Cellular Neuroscience

Preferential Targeting of Nav1.6 Voltage-Gated Na+ Channels to the Axon Initial Segment during Development

(2015) Elizabeth J. Akin et al.   PLoS One

Giant ankyrin-G: A critical innovation in vertebrate evolution of fast and integrated neuronal signaling

(2015) Paul M. Jenkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of the FGF14:FGF14 Homodimer Interaction Through Short Peptide Fragments

(2014) Syed Ali et al.   CNS & Neurological Disorders-Drug Targets

Axon initial segments: diverse and dynamic neuronal compartments

(2014) Takeshi Yoshimura et al.   CURRENT OPINION IN NEUROBIOLOGY

CK2 accumulation at the axon initial segment depends on sodium channel Nav1

(2014) Y.E. Hien et al.   FEBS LETTERS

Axon-Carrying Dendrites Convey Privileged Synaptic Input in Hippocampal Neurons

(2014) Christian Thome et al.   NEURON

Plasticity of the Axonal Trigger Zone

(2014) Ryota Adachi et al.   NEUROSCIENTIST

The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3)

(2013) Alexander S. Shavkunov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioluminescence Methodology for the Detection of Protein–Protein Interactions Within the Voltage-Gated Sodium Channel Macromolecular Complex

(2012) Alexander Shavkunov et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A Fine-Mapping Study of 7 Top Scoring Genes from a GWAS for Major Depressive Disorder

(2012) Eva C. Verbeek et al.   PLoS One

Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase

(2012) Norelle C. Wildburger et al.   Frontiers in Molecular Neuroscience

Bioinformatic Prediction and Confirmation of β-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

(2011) Hovik Farghaian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short- and Long-Term Plasticity at the Axon Initial Segment

(2011) M. S. Grubb et al.   JOURNAL OF NEUROSCIENCE

Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier

(2010) Anna Brachet et al.   JOURNAL OF CELL BIOLOGY

Casein kinase 2 and microtubules control axon initial segment formation

(2010) Diana Sanchez-Ponce et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Deficits in Syntaxin 1 Phosphorylation in Schizophrenia Prefrontal Cortex

(2009) Max A. Castillo et al.   BIOLOGICAL PSYCHIATRY

Protein Kinase CK2 in Health and Disease

(2009) K. Niefind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels

(2009) Regina Goetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels

(2009) Fernanda Laezza et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

(2008) Aline Bréchet et al.   JOURNAL OF CELL BIOLOGY

FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons

(2008) Vikram G. Shakkottai et al.   NEUROBIOLOGY OF DISEASE