Novel Influences of IL-10 on CNS Inflammation Revealed by Integrated Analyses of Cytokine Networks and Microglial Morphology

Differential transcriptional response profiles in human myeloid cell populations

(2018) Luke M. Healy et al.   CLINICAL IMMUNOLOGY

A data-driven modeling approach to identify disease-specific multi-organ networks driving physiological dysregulation

(2017) Warren D. Anderson et al.   PLoS Computational Biology

Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease

(2016) Andrew D. Greenhalgh et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

(2016) Andrea Crotti et al.   IMMUNITY

Neuroinflammation: the devil is in the details

(2016) Damon J. DiSabato et al.   JOURNAL OF NEUROCHEMISTRY

Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination

(2016) Pernille M. Madsen et al.   JOURNAL OF NEUROSCIENCE

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Microglial TNF-α Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization

(2016) Gil M. Lewitus et al.   NEURON

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex

(2016) G. O. Sipe et al.   Nature Communications

Hierarchical Cluster Analysis of Three-Dimensional Reconstructions of Unbiased Sampled Microglia Shows not Continuous Morphological Changes from Stage 1 to 2 after Multiple Dengue Infections in Callithrix penicillata

(2016) Daniel G. Diniz et al.   Frontiers in Neuroanatomy

Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling

(2016) Oihane Abiega et al.   PLOS BIOLOGY

Ultrasensitive Negative Feedback Control: A Natural Approach for the Design of Synthetic Controllers

(2016) Francesco Montefusco et al.   PLoS One

Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes

(2015) Warren D. Anderson et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Role of IL-10 in Resolution of Inflammation and Functional Recovery after Peripheral Nerve Injury

(2015) B. Siqueira Mietto et al.   JOURNAL OF NEUROSCIENCE

Computational modeling of cytokine signaling in microglia

(2015) Warren D. Anderson et al.   Molecular BioSystems

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

Dealing with Danger in the CNS: The Response of the Immune System to Injury

(2015) Sachin P. Gadani et al.   NEURON

IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

(2015) Paramita Chakrabarty et al.   NEURON

Macrophage and microglial plasticity in the injured spinal cord

(2015) S. David et al.   NEUROSCIENCE

Priming the Inflammatory Pump of the CNS after Traumatic Brain Injury

(2015) Kristina G. Witcher et al.   TRENDS IN NEUROSCIENCES

Microglia Function in Central Nervous System Development and Plasticity

(2015) Dorothy P. Schafer et al.   Cold Spring Harbor Perspectives in Biology

Beanplot: A Boxplot Alternative for Visual Comparison of Distributions

(2015) Peter Kampstra   Journal of Statistical Software

Combinatorial epigenetic patterns as quantitative predictors of chromatin biology

(2014) Marcin Cieślik et al.   BMC GENOMICS

Dynamic structural remodelling of microglia in health and disease: A review of the models, the signals and the mechanisms

(2014) F. Rohan Walker et al.   BRAIN BEHAVIOR AND IMMUNITY

Inputs drive cell phenotype variability

(2014) J. Park et al.   GENOME RESEARCH

TGFβ produced by IL-10 redirected astrocytes attenuates microglial activation

(2014) Diana M. Norden et al.   GLIA

Quantitative assessment of microglial morphology and density reveals remarkable consistency in the distribution and morphology of cells within the healthy prefrontal cortex of the rat

(2014) Ratchaniporn Kongsui et al.   Journal of Neuroinflammation

Differences in the Phagocytic Response of Microglia and Peripheral Macrophages after Spinal Cord Injury and Its Effects on Cell Death

(2014) A. D. Greenhalgh et al.   JOURNAL OF NEUROSCIENCE

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Model Reduction by Manifold Boundaries

(2014) Mark K. Transtrum et al.   PHYSICAL REVIEW LETTERS

Microglial pathology

(2014) Wolfgang J Streit et al.   Acta Neuropathologica Communications

Chronic Neuron- and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer Disease Mice Leads to Significant Modulation of Amyloid- and Tau-Related Pathologies

(2013) Sara L. Montgomery et al.   AMERICAN JOURNAL OF PATHOLOGY

Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide

(2013) C. Madore et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglial Dysregulation in Psychiatric Disease

(2013) Luciana Romina Frick et al.   Clinical & Developmental Immunology

MicroRNA-146a and RBM4 form a negative feed-forward loop that disrupts cytokine mRNA translation following TLR4 responses in human THP-1 monocytes

(2013) Laura Brudecki et al.   IMMUNOLOGY AND CELL BIOLOGY

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

A tutorial review on process identification from step or relay feedback test

(2013) Tao Liu et al.   JOURNAL OF PROCESS CONTROL

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

(2013) Amanda Sierra et al.   Frontiers in Cellular Neuroscience

Quantitating the subtleties of microglial morphology with fractal analysis

(2013) Audrey Karperien et al.   Frontiers in Cellular Neuroscience

ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury

(2013) H Ishii et al.   Cell Death & Disease

Microglia and Synapse: Interactions in Health and Neurodegeneration

(2013) Zuzana Šišková et al.   NEURAL PLASTICITY

Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis

(2012) Jun Yamada et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Differential Detection and Distribution of Microglial and Hematogenous Macrophage Populations in the Injured Spinal Cord oflys-EGFP-kiTransgenic Mice

(2012) Leah A. Mawhinney et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo

(2012) Cleopatra Kozlowski et al.   PLoS One

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice

(2011) Ashley M. Fenn et al.   BRAIN BEHAVIOR AND IMMUNITY

A flexible R package for nonnegative matrix factorization

(2010) Renaud Gaujoux et al.   BMC BIOINFORMATICS

Cytokine networks in multiple sclerosis: lost in translation

(2010) Laura Codarri et al.   CURRENT OPINION IN NEUROLOGY

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Model simplification procedure for signal transduction pathway models: An application to IL-6 signaling

(2009) Zuyi (Jacky) Huang et al.   CHEMICAL ENGINEERING SCIENCE

Microglia processes block the spread of damage in the brain and require functional chloride channels

(2009) Dustin J. Hines et al.   GLIA

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

SVD based initialization: A head start for nonnegative matrix factorization

(2007) C. Boutsidis et al.   PATTERN RECOGNITION