Behavioral Senescence and Aging-Related Changes in Motor Neurons and Brain Neuromodulator Levels Are Ameliorated by Lifespan-Extending Reproductive Dormancy in Drosophila

Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster

(2016) Lucie Kučerová et al.   BMC GENOMICS

Circadian Rhythms, Sleep, and Disorders of Aging

(2016) Joanna Mattis et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Systemic corazonin signalling modulates stress responses and metabolism inDrosophila

(2016) Olga I. Kubrak et al.   Open Biology

The Drosophila Transcription Factor Dimmed Affects Neuronal Growth and Differentiation in Multiple Ways Depending on Neuron Type and Developmental Stage

(2016) Yiting Liu et al.   Frontiers in Molecular Neuroscience

Drosophila insulin-like peptide 1 (DILP1) is transiently expressed during non-feeding stages and reproductive dormancy

(2016) Yiting Liu et al.   Scientific Reports

AgingDrosophila melanogasterdisplay altered pre- and postsynaptic ultrastructure at adult neuromuscular junctions

(2015) Nicole Wagner et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Drosophila Insulin Receptor Independently Modulates Lifespan and Locomotor Senescence

(2015) Mohd Zamri Bin Haji Ismail et al.   PLoS One

Parallel circuits control temperature preference in Drosophila during ageing

(2015) Hsiang-Wen Shih et al.   Nature Communications

PPL2ab neurons restore sexual responses in aged Drosophila males through dopamine

(2015) Shu-Yun Kuo et al.   Nature Communications

Drosophila models reveal novel insights into mechanisms underlying neurodegeneration

(2014) Ryan D Mohan et al.   FLY

Analysis of dopaminergic neuronal dysfunction in genetic and toxin-induced models of Parkinson's disease inDrosophila

(2014) Juan A. Navarro et al.   JOURNAL OF NEUROCHEMISTRY

Glial Dysfunction Causes Age-Related Memory Impairment in Drosophila

(2014) Daisuke Yamazaki et al.   NEURON

The Sleeping Beauty: How Reproductive Diapause Affects Hormone Signaling, Metabolism, Immune Response and Somatic Maintenance in Drosophila melanogaster

(2014) Olga I. Kubrak et al.   PLoS One

Lowered Insulin Signalling Ameliorates Age-Related Sleep Fragmentation in Drosophila

(2014) Athanasios Metaxakis et al.   PLOS BIOLOGY

A Genetic Strategy to Measure Circulating Drosophila Insulin Reveals Genes Regulating Insulin Production and Secretion

(2014) Sangbin Park et al.   PLoS Genetics

Mosquito Diapause

(2013) David L. Denlinger et al.   Annual Review of Entomology

Neuromodulatory control of sleep in Drosophila melanogaster: integration of competing and complementary behaviors

(2013) Leslie C Griffith   CURRENT OPINION IN NEUROBIOLOGY

Molecular Mechanisms of Age-Related Sleep Loss in the Fruit Fly - A Mini-Review

(2013) Meagan Robertson et al.   GERONTOLOGY

Life-History Evolution and the Polyphenic Regulation of Somatic Maintenance and Survival

(2013) Thomas Flatt et al.   QUARTERLY REVIEW OF BIOLOGY

A Single Dopamine Pathway Underlies Progressive Locomotor Deficits in a Drosophila Model of Parkinson Disease

(2013) Thomas Riemensperger et al.   Cell Reports

Insulin signaling and the regulation of insect diapause

(2013) Cheolho Sim et al.   Frontiers in Physiology

Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations

(2012) Wenyu Luo et al.   AGING CELL

Pigment-Dispersing Factor Is Involved in Age-Dependent Rhythm Changes in Drosophila melanogaster

(2012) Yujiro Umezaki et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Serotonin is Critical for Rewarded Olfactory Short-Term Memory in Drosophila

(2012) Divya Sitaraman et al.   JOURNAL OF NEUROGENETICS

Aging impairs intermediate-term behavioral memory by disrupting the dorsal paired medial neuron memory trace

(2012) A. Tonoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin-Producing Cells in the Drosophila Brain also Express Satiety-Inducing Cholecystokinin-Like Peptide, Drosulfakinin

(2012) Jeannette A. E. Söderberg et al.   Frontiers in Endocrinology

The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease

(2011) D.J. Surmeier et al.   NEUROSCIENCE

Circadian Rhythms, Aging, and Life Span in Mammals

(2011) Oren Froy   PHYSIOLOGY

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

Gene expression, metabolic regulation and stress tolerance during diapause

(2010) Thomas H. MacRae   CELLULAR AND MOLECULAR LIFE SCIENCES

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

(2010) Linda Partridge et al.   EXPERIMENTAL GERONTOLOGY

Drosophila as a model for age-related impairment in locomotor and other behaviors

(2010) Melanie A. Jones et al.   EXPERIMENTAL GERONTOLOGY

Chemical neuroanatomy of the Drosophila central complex: Distribution of multiple neuropeptides in relation to neurotransmitters

(2010) Lily Kahsai et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuropeptides in the Drosophila central complex in modulation of locomotor behavior

(2010) L. Kahsai et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Corazonin Neurons Function in Sexually Dimorphic Circuitry That Shape Behavioral Responses to Stress in Drosophila

(2010) Yan Zhao et al.   PLoS One

Metabolic Stress Responses in Drosophila Are Modulated by Brain Neurosecretory Cells That Produce Multiple Neuropeptides

(2010) Lily Kahsai et al.   PLoS One

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

A forward genetic screen in Drosophila implicates insulin signaling in age-related locomotor impairment

(2009) Melanie A. Jones et al.   EXPERIMENTAL GERONTOLOGY

Mushroom Bodies Enhance Initial Motor Activity indrosophila

(2009) Christine N. Serway et al.   JOURNAL OF NEUROGENETICS

DrosophilaModels of Neurodegenerative Diseases

(2008) Bingwei Lu et al.   Annual Review of Pathology-Mechanisms of Disease

Regulatory peptides in fruit fly midgut

(2008) Jan A. Veenstra et al.   CELL AND TISSUE RESEARCH

Organization of the Drosophila Circadian Control Circuit

(2008) Michael N. Nitabach et al.   CURRENT BIOLOGY

LEARNING ABILITY AND LONGEVITY: A SYMMETRICAL EVOLUTIONARY TRADE-OFF IN DROSOPHILA

(2008) Joep M. S. Burger et al.   EVOLUTION

Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed

(2008) Devin Rhodenizer et al.   EXPERIMENTAL GERONTOLOGY

Pigment-Dispersing Factor (PDF) Has Different Effects on Drosophila's Circadian Clocks in the Accessory Medulla and in the Dorsal Brain

(2008) Corinna Wülbeck et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Intrinsic neurons ofDrosophilamushroom bodies express short neuropeptide F: Relations to extrinsic neurons expressing different neurotransmitters

(2008) Helena A.D. Johard et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Ion transport peptide splice forms in central and peripheral neurons throughout postembryogenesis ofDrosophila melanogaster

(2008) Heinrich Dircksen et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

(2007) Colin Selman et al.   FASEB JOURNAL