The Drosophila Insulin Receptor Independently Modulates Lifespan and Locomotor Senescence

An electromagnetic field disrupts negative geotaxis in Drosophila via a CRY-dependent pathway

(2014) Giorgio Fedele et al.   Nature Communications

Cell-Nonautonomous Effects of dFOXO/DAF-16 in Aging

(2014) Nazif Alic et al.   Cell Reports

Cryptochromerestores dampened circadian rhythms and promotes healthspan in agingDrosophila

(2013) Kuntol Rakshit et al.   AGING CELL

Activin Signaling Targeted by Insulin/dFOXO Regulates Aging and Muscle Proteostasis in Drosophila

(2013) Hua Bai et al.   PLoS Genetics

Distribution of metabotropic receptors of serotonin, dopamine, GABA, glutamate, and short neuropeptide F in the central complex of Drosophila

(2012) L. Kahsai et al.   NEUROSCIENCE

Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

(2012) Derek A. Costello et al.   PLoS One

The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency

(2011) Jenq-Lin Yang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition

(2010) Susan J. Broughton et al.   AGING CELL

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

Drosophila as a model for age-related impairment in locomotor and other behaviors

(2010) Melanie A. Jones et al.   EXPERIMENTAL GERONTOLOGY

Chemical neuroanatomy of the Drosophila central complex: Distribution of multiple neuropeptides in relation to neurotransmitters

(2010) Lily Kahsai et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Object preference by walking fruit flies, Drosophila melanogaster, is mediated by vision and graviperception

(2010) A. A. Robie et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

Insulin/IGF-like signalling, the central nervous system and aging

(2009) Susan Broughton et al.   BIOCHEMICAL JOURNAL

A forward genetic screen in Drosophila implicates insulin signaling in age-related locomotor impairment

(2009) Melanie A. Jones et al.   EXPERIMENTAL GERONTOLOGY

Mushroom Bodies Enhance Initial Motor Activity indrosophila

(2009) Christine N. Serway et al.   JOURNAL OF NEUROGENETICS

Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease

(2009) F. Kerr et al.   NEUROBIOLOGY OF AGING

The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila

(2009) T. Ikeya et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

LEARNING ABILITY AND LONGEVITY: A SYMMETRICAL EVOLUTIONARY TRADE-OFF IN DROSOPHILA

(2008) Joep M. S. Burger et al.   EVOLUTION

Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed

(2008) Devin Rhodenizer et al.   EXPERIMENTAL GERONTOLOGY

Comment on "Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis"

(2008) C. Selman et al.   SCIENCE

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

(2007) Colin Selman et al.   FASEB JOURNAL