Lowered Insulin Signalling Ameliorates Age-Related Sleep Fragmentation in Drosophila

A Dynamic Deep Sleep Stage in Drosophila

(2013) B. van Alphen et al.   JOURNAL OF NEUROSCIENCE

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

(2012) Stacey Robida-Stubbs et al.   Cell Metabolism

Interaction between Sleep and Metabolism inDrosophilawith Altered Octopamine Signaling

(2012) Renske Erion et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

(2012) J. Halloran et al.   NEUROSCIENCE

Diet promotes sleep duration and quality

(2012) Katri Peuhkuri et al.   NUTRITION RESEARCH

Re-Patterning Sleep Architecture in Drosophila through Gustatory Perception and Nutritional Quality

(2012) Nancy J. Linford et al.   PLoS Genetics

Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles

(2011) Cagdas Tazearslan et al.   AGING CELL

dFOXO-independent effects of reduced insulin-like signaling inDrosophila

(2011) Cathy Slack et al.   AGING CELL

High calorie diet augments age-associats sleep impairment in Drosophila

(2011) Masako Yamazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fighting the famine with an amine: synaptic strategies for smart search

(2011) Stephan J Sigrist et al.   NATURE NEUROSCIENCE

insomniac and Cullin-3 Regulate Sleep and Wakefulness in Drosophila

(2011) Nicholas Stavropoulos et al.   NEURON

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling

(2010) Alex C Koon et al.   NATURE NEUROSCIENCE

Identification of a Neural Circuit that Underlies the Effects of Octopamine on Sleep:Wake Behavior

(2010) Amanda Crocker et al.   NEURON

Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization

(2010) J. Wu et al.   NEUROSCIENCE

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

(2010) C. Kenyon   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

The Perilipin Homologue, Lipid Storage Droplet 2, Regulates Sleep Homeostasis and Prevents Learning Impairments Following Sleep Loss

(2010) Matthew S. Thimgan et al.   PLOS BIOLOGY

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

Insulin/IGF-like signalling, the central nervous system and aging

(2009) Susan Broughton et al.   BIOCHEMICAL JOURNAL

Enhanced Dopamine D1 and D2 Receptor Gene Expression in the Hippocampus of Hypoglycaemic and Diabetic Rats

(2009) Remya Robinson et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

(2009) Luke S Tain et al.   NATURE NEUROSCIENCE

Effects of poor and short sleep on glucose metabolism and obesity risk

(2009) Karine Spiegel et al.   Nature Reviews Endocrinology

The genetic and molecular regulation of sleep: from fruit flies to humans

(2009) Chiara Cirelli   NATURE REVIEWS NEUROSCIENCE

Two Different Forms of Arousal in Drosophila Are Oppositely Regulated by the Dopamine D1 Receptor Ortholog DopR via Distinct Neural Circuits

(2009) Tim Lebestky et al.   NEURON

The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila

(2009) T. Ikeya et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sleep and its disorders in aging populations

(2009) Sonia Ancoli-Israel   SLEEP MEDICINE

What are microarrays teaching us about sleep?

(2009) Miroslaw Mackiewicz et al.   TRENDS IN MOLECULAR MEDICINE

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Opposing Effects of Dietary Protein and Sugar Regulate a Transcriptional Target of Drosophila Insulin-like Peptide Signaling

(2008) Susanne Buch et al.   Cell Metabolism

A glucagon-like endocrine pathway in Drosophila modulates both lipid and carbohydrate homeostasis

(2008) K. N. Bharucha et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Octopamine Regulates Sleep in Drosophila through Protein Kinase A-Dependent Mechanisms

(2008) A. Crocker et al.   JOURNAL OF NEUROSCIENCE

The insulin paradox: aging, proteotoxicity and neurodegeneration

(2008) Ehud Cohen et al.   NATURE REVIEWS NEUROSCIENCE

A PI3-Kinase–Mediated Negative Feedback Regulates Neuronal Excitability

(2008) Eric Howlett et al.   PLoS Genetics

Administration of the protein synthesis inhibitor, anisomycin, has distinct sleep-promoting effects in lateral preoptic and perifornical hypothalamic sites in rats

(2007) M.M. Methippara et al.   NEUROSCIENCE