Direct Cα-heteroarylation of structurally diverse ethers via a mild N-hydroxysuccinimide mediated cross-dehydrogenative coupling reaction

Visible light-promoted C–H functionalization of ethers and electron-deficient arenes

(2016) Shekaraiah Devari et al.   CHEMICAL COMMUNICATIONS

Fe-Catalyzed Amination of (Hetero)Arenes with a Redox-Active Aminating Reagent under Mild Conditions

(2016) Jianzhong Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine C-Nucleosides as Favipiravir (T-705) Analogues

(2016) Guangyi Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cobalt-Catalyzed Cross-Dehydrogenative Coupling Reactions of (Benz)oxazoles with Ethers

(2016) Yanrong Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C–H Functionalization of Trialkylamine N-CH3 Groups

(2016) Joshua P. Barham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amide-directed photoredox-catalysed C–C bond formation at unactivated sp3 C–H bonds

(2016) John C. K. Chu et al.   NATURE

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer

(2016) Gilbert J. Choi et al.   NATURE

Oxidative coupling between C(sp2)–H and C(sp3)–H bonds of indoles and cyclic ethers/cycloalkanes

(2016) Qingjing Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

(2016) M. H. Shaw et al.   SCIENCE

Direct α-heteroarylation of amides (α to nitrogen) and ethers through a benzaldehyde-mediated photoredox reaction

(2016) Yongqiang Zhang et al.   Chemical Science

Discovery of G Protein-Biased EP2 Receptor Agonists

(2016) Seiji Ogawa et al.   ACS Medicinal Chemistry Letters

Formation of Carbonyl Compounds from Amines through Oxidative CN Bond Cleavage using Visible Light Photocatalysis and Applications toN-PMB-Amide Deprotection

(2015) Naeem Iqbal et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of stereochemically diverse cyclic analogs of tubulysins

(2015) Yunjeong Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease

(2015) Jian Jeffrey Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Iron-catalyzed direct α-arylation of ethers with azoles

(2015) Arkaitz Correa et al.   CHEMICAL COMMUNICATIONS

Introduction of Ether Groups onto Electron-Deficient Nitrogen-Containing Heteroaromatics Using Radical Chemistry under Transition-Metal-Free Conditions

(2015) Naoki Okugawa et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

C-Nucleosides To Be Revisited

(2015) Erik De Clercq   JOURNAL OF MEDICINAL CHEMISTRY

Cross-dehydrogenative coupling of α-C(sp3)–H of ethers/alkanes with C(sp2)–H of heteroarenes under metal-free conditions

(2015) Srinivas Ambala et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nickel-Catalyzed Regioselective Cross-Dehydrogenative Coupling of Inactive C(sp3)–H Bonds with Indole Derivatives

(2015) Li-Kun Jin et al.   ORGANIC LETTERS

O-H hydrogen bonding promotes H-atom transfer from   C-H bonds for C-alkylation of alcohols

(2015) J. L. Jeffrey et al.   SCIENCE

Highly Chemoselective and Regioselective Dehydrogenative Cross-Coupling Reaction between Pyridines and Ethers

(2015) Zhi-Zhen Huang et al.   SYNLETT

Use of Isosorbide Dinitrate and Hydralazine in African-Americans With Heart Failure 9 Years After the African-American Heart Failure Trial

(2014) Keith Copelin Ferdinand et al.   AMERICAN JOURNAL OF CARDIOLOGY

Direct α-Arylation of Ethers through the Combination of Photoredox-Mediated CH Functionalization and the Minisci Reaction

(2014) Jian Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

N-Acyloxyphthalimides as Nitrogen Radical Precursors in the Visible Light Photocatalyzed Room Temperature C–H Amination of Arenes and Heteroarenes

(2014) Laura J. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Addition to Iminium Ions and Cationic Heterocycles

(2014) Johannes Tauber et al.   MOLECULES

The Cross-Dehydrogenative Coupling of C sp 3H Bonds: A Versatile Strategy for CC Bond Formations

(2013) Simon A. Girard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Selective Oxidative Cross-Coupling of Simple Alkanes with Heteroarenes

(2013) Andrey P. Antonchick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Transition-metal-free cross-dehydrogenative alkylation of pyridines under neutral conditions

(2013) Xin Li et al.   NEW JOURNAL OF CHEMISTRY

Cu-Catalyzed Cross-Dehydrogenative Coupling Reactions of (Benzo)thiazoles with Cyclic Ethers

(2013) Zengyang Xie et al.   ORGANIC LETTERS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct C2-Alkylation of Azoles with Alcohols and Ethers through Dehydrogenative Cross-Coupling under Metal-Free Conditions

(2011) Tao He et al.   ORGANIC LETTERS

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

(2011) Matthew A. J. Duncton   MedChemComm

Beyond Traditional Cross Couplings: The Scope of the Cross Dehydrogenative Coupling Reaction

(2010) Caroline J. Scheuermann   Chemistry-An Asian Journal

C-Nucleosides: Synthetic Strategies and Biological Applications

(2009) Michal Hocek   CHEMICAL REVIEWS

Electron-Transfer Photoredox Catalysis: Development of a Tin-Free Reductive Dehalogenation Reaction

(2009) Jagan M. R. Narayanam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY