Melatonin-mediated Bim up-regulation and cyclooxygenase-2 (COX-2) down-regulation enhances tunicamycin-induced apoptosis in MDA-MB-231 cells

Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cells

(2014) Sara Proietti et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Combined with Endoplasmic Reticulum Stress Induces Cell Death via the PI3K/Akt/mTOR Pathway in B16F10 Melanoma Cells

(2014) Han Sung Kim et al.   PLoS One

Melatonin reverses tunicamycin-induced endoplasmic reticulum stress in human hepatocellular carcinoma cells and improves cytotoxic response to doxorubicin by increasing CHOP and decreasing Survivin

(2013) Lulu Fan et al.   JOURNAL OF PINEAL RESEARCH

Molecular deficiency (ies) in MT1melatonin signaling pathway underlies the melatonin-unresponsive phenotype in MDA-MB-231 human breast cancer cells

(2013) Lulu Mao et al.   JOURNAL OF PINEAL RESEARCH

Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes

(2012) Zafar Rasheed et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials

(2012) Ye-min Wang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells

(2012) Abdulhadi C. Uguz et al.   JOURNAL OF PINEAL RESEARCH

Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model

(2012) Kil-Jung Kim et al.   JOURNAL OF PINEAL RESEARCH

Biology of Cox-2: An Application in Cancer Therapeutics

(2011) Zakir Khan et al.   CURRENT DRUG TARGETS

Melatonin prevents human pancreatic carcinoma cell PANC-1-induced human umbilical vein endothelial cell proliferation and migration by inhibiting vascular endothelial growth factor expression

(2011) Peilin Cui et al.   JOURNAL OF PINEAL RESEARCH

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

(2011) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis

(2011) Lixia Zha et al.   JOURNAL OF PINEAL RESEARCH

Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity

(2011) Kyoung-Jin Min et al.   JOURNAL OF PINEAL RESEARCH

Molecular Mechanisms of System Control of NF-κB Signaling by IκBα

(2010) Diego U. Ferreiro et al.   BIOCHEMISTRY

Melatonin signaling and cell protection function

(2010) Francesca Luchetti et al.   FASEB JOURNAL

Melatonin in septic shock: Some recent concepts

(2010) Venkataramanujan Srinivasan et al.   JOURNAL OF CRITICAL CARE

In vitro and in vivo antitumor activity of melatonin receptor agonists

(2010) Lulu Mao et al.   JOURNAL OF PINEAL RESEARCH

Matrix metalloproteinases in health and disease: regulation by melatonin

(2010) Snehasikta Swarnakar et al.   JOURNAL OF PINEAL RESEARCH

Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)

(2010) Anna Leja-Szpak et al.   JOURNAL OF PINEAL RESEARCH

Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

(2009) Wendy L. Thompson et al.   BRAIN RESEARCH

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells

(2009) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

Reactions of the melatonin metaboliteN1-acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds

(2009) Jana T. Kuesel et al.   JOURNAL OF PINEAL RESEARCH

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

(2009) Brittney Jung-Hynes et al.   JOURNAL OF PINEAL RESEARCH

Alteration of the MT1 melatonin receptor gene and its expression in primary human breast tumors and breast cancer cell lines

(2008) Ling Lai et al.   BREAST CANCER RESEARCH AND TREATMENT