Nigericin decreases the viability of multidrug-resistant cancer cells and lung tumorspheres and potentiates the effects of cardiac glycosides

Wnt signaling as potential therapeutic target in lung cancer

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Wnt signalling is a bi-directional vulnerability of cancer cells

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Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model

(2016) Juan Sebastian Yakisich et al.   Stem Cells International

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells

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Digitoxin and its synthetic analog MonoD have potent antiproliferative effects on lung cancer cells and potentiate the effects of hydroxyurea and paclitaxel

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Early effects of the antineoplastic agent salinomycin on mitochondrial function

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Hypoxia and TGF-β1 lead to endostatin resistance by cooperatively increasing cancer stem cells in A549 transplantation tumors

(2015) Yuyi Wang et al.   Cell and Bioscience

Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics

(2015) Maximilian Boesch et al.   Stem Cells Translational Medicine

Cardiac Glycoside Activities Link Na+/K+ ATPase Ion-Transport to Breast Cancer Cell Migration via Correlative SAR

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DEPDC1B enhances migration and invasion of non-small cell lung cancer cells via activating Wnt/β-catenin signaling

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Lung mesenchymal cells function as an inductive microenvironment for human lung cancer propagating cells†

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Intratumour heterogeneity in lung cancer

(2014) Farhat Yaqub   LANCET ONCOLOGY

Tumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives

(2014) Haiquan Chen et al.   OncoTargets and Therapy

Opportunities to address lung cancer disparities among African Americans

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Wnt Modulating Agents Inhibit Human Cytomegalovirus Replication

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Monensin, a polyether ionophore antibiotic, overcomes TRAIL resistance in glioma cells via endoplasmic reticulum stress, DR5 upregulation and c-FLIP downregulation

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Nigericin selectively targets cancer stem cells in nasopharyngeal carcinoma

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Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction

(2013) Sheng Wang et al.   Nature Chemical Biology

Premature myocardial infarction is associated with low serum levels of Wnt-1

(2012) Georg Goliasch et al.   ATHEROSCLEROSIS

Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy

(2012) Toshio Kubo et al.   CANCER SCIENCE

Multifunctional Role of Bcl-2 in Malignant Transformation and Tumorigenesis of Cr(VI)-Transformed Lung Cells

(2012) Djordje Medan et al.   PLoS One

Suppression of colorectal cancer metastasis by nigericin through inhibition of epithelial-mesenchymal transition

(2012) Hou-Min Zhou   WORLD JOURNAL OF GASTROENTEROLOGY

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

(2011) Desheng Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor

(2010) Roberta Riccioni et al.   BLOOD CELLS MOLECULES AND DISEASES

Controversies in Cancer Stem Cells: Targeting Embryonic Signaling Pathways

(2010) N. Takebe et al.   CLINICAL CANCER RESEARCH

Myristoylated Naked2 Antagonizes Wnt-β-Catenin Activity by Degrading Dishevelled-1 at the Plasma Membrane

(2010) Tianhui Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides

(2010) Anand Krishnan V. Iyer et al.   ACS Medicinal Chemistry Letters

Architectural Heterogeneity in Tumors Caused by Differentiation Alters Intratumoral Drug Distribution and Affects Therapeutic Synergy of Antiangiogenic Organoselenium Compound

(2010) Youcef M. Rustum et al.   Journal of Oncology

Nitric Oxide–Mediated Bcl-2 Stabilization Potentiates Malignant Transformation of Human Lung Epithelial Cells

(2009) Neelam Azad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction

(2008) Bikul Das et al.   STEM CELLS