U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells

Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiationin vitro

(2016) Hubert Monnerie et al.   JOURNAL OF NEUROCHEMISTRY

Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line

(2016) Mathieu Schmitt et al.   SYNAPSE

Inhibiting Geranylgeranylation Increases Neurite Branching and Differentially Activates Cofilin in Cell Bodies and Growth Cones

(2014) Filsy Samuel et al.   MOLECULAR NEUROBIOLOGY

The vesicular monoamine transporter 2: An underexplored pharmacological target

(2014) Alison I. Bernstein et al.   NEUROCHEMISTRY INTERNATIONAL

Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

(2014) Kelly M. Lohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease

(2013) Adalberto A. Castro et al.   BRAIN RESEARCH

A role for Sv2c in basal ganglia functions

(2013) D. Dardou et al.   BRAIN RESEARCH

Analysis of vesicular monoamine transporter 2 polymorphisms in Parkinson’s disease

(2013) Laura Brighina et al.   NEUROBIOLOGY OF AGING

Discontinuation of statin therapy associates with Parkinson disease: A population-based study

(2013) Y.-C. Lee et al.   NEUROLOGY

Simvastatin Induced Neurite Outgrowth Unveils Role of Cell Surface Cholesterol and Acetyl CoA Carboxylase in SH-SY5Y Cells

(2013) Varshiesh Raina et al.   PLoS One

Simvastatin Promotes Adult Hippocampal Neurogenesis by Enhancing Wnt/β-Catenin Signaling

(2013) Nicholas C. Robin et al.   Stem Cell Reports

Atorvastatin enhances neurite outgrowth in cortical neurons in vitro via up-regulating the Akt/mTOR and Akt/GSK-3β signaling pathways

(2012) Ying Jin et al.   ACTA PHARMACOLOGICA SINICA

Prospective Study of Statin Use and Risk of Parkinson Disease

(2012) Xiang Gao   ARCHIVES OF NEUROLOGY

Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms

(2012) Anil Kumar et al.   BRAIN RESEARCH

Expanding Roles for SREBP in Metabolism

(2012) Wei Shao et al.   Cell Metabolism

Simvastatin Induces Neuroprotection in 6-OHDA-Lesioned PC12 via the PI3K/AKT/Caspase 3 Pathway and Anti-Inflammatory Responses

(2012) Yun-Qi Xu et al.   CNS Neuroscience & Therapeutics

Atorvastatin stimulates neuroblastoma cells to induce neurite outgrowth by increasing cellular prion protein expression

(2012) Takuya Watanabe et al.   NEUROSCIENCE LETTERS

Human Subtilase SKI-1/S1P Is a Master Regulator of the HCV Lifecycle and a Potential Host Cell Target for Developing Indirect-Acting Antiviral Agents

(2012) Andrea D. Olmstead et al.   PLoS Pathogens

Prospects of Statins in Parkinson Disease

(2011) Avik Roy et al.   NEUROSCIENTIST

Simvastatin Prevents Dopaminergic Neurodegeneration in Experimental Parkinsonian Models: The Association with Anti-Inflammatory Responses

(2011) Junqiang Yan et al.   PLoS One

Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system

(2010) D. Dardou et al.   BRAIN RESEARCH

Simvastatin Inhibits the Activation of p21ras and Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

(2009) A. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Physical and Functional Interaction between the Dopamine Transporter and the Synaptic Vesicle Protein Synaptogyrin-3

(2009) L. A. Egana et al.   JOURNAL OF NEUROSCIENCE

Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR

(2009) M. E. Evangelopoulos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cholesterol Synthesis Inhibitor U18666A and the Role of Sterol Metabolism and Trafficking in Numerous Pathophysiological Processes

(2009) Richard J. Cenedella   LIPIDS

Pharmacologic Inhibition of Site 1 Protease Activity Inhibits Sterol Regulatory Element-Binding Protein Processing and Reduces Lipogenic Enzyme Gene Expression and Lipid Synthesis in Cultured Cells and Experimental Animals

(2008) J. L. Hawkins et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Statin use and the risk of Parkinson disease

(2008) A. D. Wahner et al.   NEUROLOGY