Inhibiting Geranylgeranylation Increases Neurite Branching and Differentially Activates Cofilin in Cell Bodies and Growth Cones

Efficient Use of Exogenous Isoprenols for Protein Isoprenylation by MDA-MB-231 Cells Is Regulated Independently of the Mevalonate Pathway

(2013) Fredrick Onono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Farnesyltransferase Haplodeficiency Reduces Neuropathology and Rescues Cognitive Function in a Mouse Model of Alzheimer Disease

(2013) Shaowu Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis

(2013) W. Gibson Wood et al.   JOURNAL OF NEUROCHEMISTRY

Atorvastatin requires geranylgeranyl transferase-I and Rac1 activation to exert neuronal protection and induce plasticity

(2013) Rafael Andrés Posada-Duque et al.   NEUROCHEMISTRY INTERNATIONAL

Brain Isoprenoids Farnesyl Pyrophosphate and Geranylgeranyl Pyrophosphate are Increased in Aged Mice

(2012) Gero P. Hooff et al.   MOLECULAR NEUROBIOLOGY

Isoprenoids and Related Pharmacological Interventions: Potential Application in Alzheimer’s Disease

(2012) Ling Li et al.   MOLECULAR NEUROBIOLOGY

Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation

(2011) R.A. Mans et al.   NEUROSCIENCE

3-Hydroxy-3-methylglutaryl–Coenzyme A Reductase Inhibitors in the Treatment of Central Nervous System Diseases

(2010) Joshua Z. Willey et al.   ARCHIVES OF NEUROLOGY

RHO GTPase Signaling for Axon Extension: Is Prenylation Important?

(2010) Filsy Samuel et al.   MOLECULAR NEUROBIOLOGY

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

(2009) Shuh Narumiya et al.   CANCER AND METASTASIS REVIEWS

Wnt5a Mediates Nerve Growth Factor-Dependent Axonal Branching and Growth in Developing Sympathetic Neurons

(2009) D. Bodmer et al.   JOURNAL OF NEUROSCIENCE

Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR

(2009) M. E. Evangelopoulos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients

(2009) Gunter P. Eckert et al.   NEUROBIOLOGY OF DISEASE

A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction

(2009) Maria Elephteria Evangelopoulos et al.   NEUROSCIENCE LETTERS

Pleiotropic Effects and Cholesterol-Lowering Therapy

(2008) Steven M. Shaw et al.   CARDIOLOGY

Rho Family GTPase Modification and Dependence on CAAXMotif-signaled Posttranslational Modification

(2008) Patrick J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

(2008) Corina Sarmiento et al.   JOURNAL OF CELL BIOLOGY

Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation

(2008) Woo-Yang Kim et al.   JOURNAL OF NEUROCHEMISTRY

Differential activation of Rac1 and RhoA in neuroblastoma cell fractions

(2008) Jennifer L. Seifert et al.   NEUROSCIENCE LETTERS