Simvastatin Induces Neuroprotection in 6-OHDA-Lesioned PC12 via the PI3K/AKT/Caspase 3 Pathway and Anti-Inflammatory Responses

Lovastatin Induces Neuroprotection Through Tumor Necrosis Factor Receptor 2 Signaling Pathways

(2017) Amalia M. Dolga et al.   JOURNAL OF ALZHEIMERS DISEASE

Extracellular signal-regulated kinase is involved in alpha-synuclein-induced mitochondrial dynamic disorders by regulating dynamin-like protein 1

(2012) Ya-Xing Gui et al.   NEUROBIOLOGY OF AGING

The Role of Alpha-Synuclein in Melanin Synthesis in Melanoma and Dopaminergic Neuronal Cells

(2012) Tianhong Pan et al.   PLoS One

Kinases and kinase signaling pathways: Potential therapeutic targets in Parkinson's disease

(2012) Gang Wang et al.   PROGRESS IN NEUROBIOLOGY

Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Against Apoptosis

(2011) Tommy Seaborn et al.   CURRENT PHARMACEUTICAL DESIGN

Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma

(2011) Masanobu Tsubaki et al.   CYTOKINE

PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression

(2011) Chi Bun Chan et al.   EMBO JOURNAL

CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease

(2011) Shi Zhang et al.   Journal of Neuroinflammation

Phosphoinositide 3-Kinase Enhancer Regulates Neuronal Dendritogenesis and Survival in Neocortex

(2011) C. Bun Chan et al.   JOURNAL OF NEUROSCIENCE

Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons

(2011) Aurelio Vazquez de la Torre et al.   NEUROCHEMISTRY INTERNATIONAL

Simvastatin Prevents Dopaminergic Neurodegeneration in Experimental Parkinsonian Models: The Association with Anti-Inflammatory Responses

(2011) Junqiang Yan et al.   PLoS One

α7 Nicotinic Acetylcholine Receptor Agonism Confers Neuroprotection Through GSK-3β Inhibition in a Mouse Model of Intracerebral Hemorrhage

(2011) Paul R. Krafft et al.   STROKE

3-Hydroxy-3-methylglutaryl–Coenzyme A Reductase Inhibitors in the Treatment of Central Nervous System Diseases

(2010) Joshua Z. Willey et al.   ARCHIVES OF NEUROLOGY

Statins: Multiple neuroprotective mechanisms in neurodegenerative diseases

(2010) Qing Wang et al.   EXPERIMENTAL NEUROLOGY

Interaction between α-synuclein and tau in Parkinson's disease

(2010) Kurt A. Jellinger   EXPERIMENTAL NEUROLOGY

Interferon-β induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK-STAT signaling and down-regulation of PI3K/Akt pathway

(2010) Simona Dedoni et al.   JOURNAL OF NEUROCHEMISTRY

The dopamine transporter is differentially regulated after dopaminergic lesion

(2010) Domingo Afonso-Oramas et al.   NEUROBIOLOGY OF DISEASE

Lovastatin Inhibits VEGFR and AKT Activation: Synergistic Cytotoxicity in Combination with VEGFR Inhibitors

(2010) Tong T. Zhao et al.   PLoS One

Overexpression of human selenoprotein H in neuronal cells ameliorates ultraviolet irradiation-induced damage by modulating cell signaling pathways

(2009) Natalia Mendelev et al.   EXPERIMENTAL NEUROLOGY

Simvastatin Inhibits the Activation of p21ras and Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

(2009) A. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Statins: Mechanisms of neuroprotection

(2009) Peter J. van der Most et al.   PROGRESS IN NEUROBIOLOGY

l-DOPA-induced neurotoxicity is reduced by the activation of the PI3K signaling pathway

(2009) Hyun-Hee Park et al.   TOXICOLOGY

Regulation of ceramide-induced neuronal death: Cell metabolism meets neurodegeneration

(2008) Gonzalo Arboleda et al.   BRAIN RESEARCH REVIEWS

High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: The association with the up-regulation of NMDA receptor binding in the rat brain

(2008) Qing Wang et al.   EXPERIMENTAL NEUROLOGY

Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine

(2008) Jezabel Rodriguez-Blanco et al.   JOURNAL OF NEUROCHEMISTRY

Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide

(2008) María del Carmen Hernández-Romero et al.   JOURNAL OF NEUROCHEMISTRY

Protective effects of erythropoietin on tau phosphorylation induced by β-amyloid

(2008) Zhi-kun Sun et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase

(2008) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Simvastatin-Mediated Upregulation of VEGF and BDNF, Activation of the PI3K/Akt Pathway, and Increase of Neurogenesis Are Associated with Therapeutic Improvement after Traumatic Brain Injury

(2008) Hongtao Wu et al.   JOURNAL OF NEUROTRAUMA