Ribosome structural dynamics in translocation: yet another functional role for ribosomal RNA

Recurring RNA structural motifs underlie the mechanics of L1 stalk movement

(2017) Srividya Mohan et al.   Nature Communications

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Choreography of molecular movements during ribosome progression along mRNA

(2016) Riccardo Belardinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Elongation factor G initiates translocation through a power stroke

(2016) Chunlai Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translocation as continuous movement through the ribosome

(2016) Riccardo Belardinelli et al.   RNA Biology

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Choreography of molecular movements during ribosome progression along mRNA

(2016) Riccardo Belardinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Kinetics of Spontaneous and EF-G-Accelerated Rotation of Ribosomal Subunits

(2016) Heena Sharma et al.   Cell Reports

Structural insights into ribosome translocation

(2016) Clarence Ling et al.   Wiley Interdisciplinary Reviews-RNA

The mechanics of ribosomal translocation

(2015) John Achenbach et al.   BIOCHIMIE

Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

(2015) Jinzhong Lin et al.   CELL

Movement of Elongation Factor G between Compact and Extended Conformations

(2015) Enea Salsi et al.   JOURNAL OF MOLECULAR BIOLOGY

Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome

(2015) Sarah Adio et al.   Nature Communications

Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis

(2014) Wolf Holtkamp et al.   BIOESSAYS

EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon–anticodon duplex

(2014) Guangqiao Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation

(2014) J. Zhou et al.   SCIENCE

Noninvasive Measurement of the Mechanical Force Generated by Motor Protein EF-G during Ribosome Translocation

(2013) Li Yao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simulating movement of tRNA through the ribosome during hybrid-state formation

(2013) Paul C. Whitford et al.   JOURNAL OF CHEMICAL PHYSICS

Coordinated conformational and compositional dynamics drive ribosome translocation

(2013) Jin Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Energy barriers and driving forces in tRNA translocation through the ribosome

(2013) Lars V Bock et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation

(2013) D. J. F. Ramrath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation

(2013) J. Zhou et al.   SCIENCE

Control of Ribosomal Subunit Rotation by Elongation Factor G

(2013) A. Pulk et al.   SCIENCE

Elongation Factor G Bound to the Ribosome in an Intermediate State of Translocation

(2013) D. S. Tourigny et al.   SCIENCE

Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome

(2013) Paul C. Whitford et al.   PLoS Computational Biology

Intermediate states during mRNA–tRNA translocation

(2012) Joachim Frank   CURRENT OPINION IN STRUCTURAL BIOLOGY

Unraveling the dynamics of ribosome translocation

(2012) Jin Chen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure and mechanical properties of the ribosomal L1 stalk three-way junction

(2012) Kamila Réblová et al.   NUCLEIC ACIDS RESEARCH

Rotation of the head of the 30S ribosomal subunit during mRNA translocation

(2012) Z. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation

(2012) D. N. Ermolenko et al.   RNA

The ribosome as a molecular machine: the mechanism of tRNA–mRNA movement in translocation

(2011) Marina V. Rodnina et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Single-Molecule Fluorescence Measurements of Ribosomal Translocation Dynamics

(2011) Chunlai Chen et al.   MOLECULAR CELL

Messenger RNA interactions in the decoding center control the rate of translocation

(2011) Prashant K Khade et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

mRNA translocation occurs during the second step of ribosomal intersubunit rotation

(2011) Dmitri N Ermolenko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insights into the molecular determinants of EF-G catalyzed translocation

(2011) L. Wang et al.   RNA

Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding

(2011) J. A. Dunkle et al.   SCIENCE

Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome

(2010) Joachim Frank et al.   Annual Review of Biochemistry

Single-Molecule Study of Ribosome Hierarchic Dynamics at the Peptidyl Transferase Center

(2010) Mediha Esra Altuntop et al.   BIOPHYSICAL JOURNAL

The Role of L1 Stalk–tRNA Interaction in the Ribosome Elongation Cycle

(2010) Leonardo G. Trabuco et al.   JOURNAL OF MOLECULAR BIOLOGY

Real-time tRNA transit on single translating ribosomes at codon resolution

(2010) Sotaro Uemura et al.   NATURE

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

(2010) Niels Fischer et al.   NATURE

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

(2010) Andreas H. Ratje et al.   NATURE

Structural aspects of messenger RNA reading frame maintenance by the ribosome

(2010) Lasse B Jenner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A fast dynamic mode of the EF-G-bound ribosome

(2009) James B Munro et al.   EMBO JOURNAL

Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation

(2009) J. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Following movement of the L1 stalk between three functional states in single ribosomes

(2009) Peter V. Cornish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spontaneous formation of the unlocked state of the ribosome is a multistep process

(2009) J. B. Munro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

(2009) Y.-G. Gao et al.   SCIENCE

Navigating the ribosome's metastable energy landscape

(2009) James B. Munro et al.   TRENDS IN BIOCHEMICAL SCIENCES

Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

(2008) Wen Li et al.   EMBO JOURNAL

Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome

(2008) Xabier Agirrezabala et al.   MOLECULAR CELL

Coupling of Ribosomal L1 Stalk and tRNA Dynamics during Translation Elongation

(2008) Jingyi Fei et al.   MOLECULAR CELL

Spontaneous Intersubunit Rotation in Single Ribosomes

(2008) Peter V. Cornish et al.   MOLECULAR CELL

Following translation by single ribosomes one codon at a time

(2008) Jin-Der Wen et al.   NATURE

Irreversible chemical steps control intersubunit dynamics during translation

(2008) R. A. Marshall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of ratcheted ribosomes with tRNAs in hybrid states

(2008) P. Julian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA