Elongation factor G initiates translocation through a power stroke

Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

(2016) Mikael Holm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

(2015) Jinzhong Lin et al.   CELL

Movement of Elongation Factor G between Compact and Extended Conformations

(2015) Enea Salsi et al.   JOURNAL OF MOLECULAR BIOLOGY

Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome

(2015) Sarah Adio et al.   Nature Communications

GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

(2014) W. Holtkamp et al.   EMBO JOURNAL

EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon–anticodon duplex

(2014) Guangqiao Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The ribosome uses cooperative conformational changes to maximize and regulate the efficiency of translation

(2014) W. Ning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Following movement of domain IV of elongation factor G during ribosomal translocation

(2014) Enea Salsi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation

(2014) J. Zhou et al.   SCIENCE

Direct measurement of the mechanical work during translocation by the ribosome

(2014) Tingting Liu et al.   eLife

Noninvasive Measurement of the Mechanical Force Generated by Motor Protein EF-G during Ribosome Translocation

(2013) Li Yao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tilting and Wobble of Myosin V by High-Speed Single-Molecule Polarized Fluorescence Microscopy

(2013) John F. Beausang et al.   BIOPHYSICAL JOURNAL

Coordinated conformational and compositional dynamics drive ribosome translocation

(2013) Jin Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamics of translation by single ribosomes through mRNA secondary structures

(2013) Chunlai Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation

(2013) D. J. F. Ramrath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the ribosome with elongation factor G trapped in the pretranslocation state

(2013) A. F. Brilot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation

(2013) J. Zhou et al.   SCIENCE

Control of Ribosomal Subunit Rotation by Elongation Factor G

(2013) A. Pulk et al.   SCIENCE

Elongation Factor G Bound to the Ribosome in an Intermediate State of Translocation

(2013) D. S. Tourigny et al.   SCIENCE

Kinetic Schemes for Post-Synchronized Single Molecule Dynamics

(2012) Chunlai Chen et al.   BIOPHYSICAL JOURNAL

FRET-Based Identification of mRNAs Undergoing Translation

(2012) Benjamin Stevens et al.   PLoS One

Structural characterization of mRNA-tRNA translocation intermediates

(2012) X. Agirrezabala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation

(2012) D. N. Ermolenko et al.   RNA

Single-Molecule Fluorescence Measurements of Ribosomal Translocation Dynamics

(2011) Chunlai Chen et al.   MOLECULAR CELL

mRNA translocation occurs during the second step of ribosomal intersubunit rotation

(2011) Dmitri N Ermolenko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular dynamics of EF-G during translocation

(2011) Wen Li et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Fluorescent labeling of tRNA dihydrouridine residues: Mechanism and distribution

(2011) J. Kaur et al.   RNA

Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding

(2011) J. A. Dunkle et al.   SCIENCE

Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome

(2010) Joachim Frank et al.   Annual Review of Biochemistry

Single-Molecule Study of Viomycin’s Inhibition Mechanism on Ribosome Translocation

(2010) Cindy T. Ly et al.   BIOCHEMISTRY

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

(2010) Niels Fischer et al.   NATURE

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

(2010) Andreas H. Ratje et al.   NATURE

The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome

(2010) Robin E Stanley et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational changes in switch I of EF-G drive its directional cycling on and off the ribosome

(2009) Cristina Ticu et al.   EMBO JOURNAL

A fast dynamic mode of the EF-G-bound ribosome

(2009) James B Munro et al.   EMBO JOURNAL

Aminoglycoside activity observed on single pre-translocation ribosome complexes

(2009) Michael B Feldman et al.   Nature Chemical Biology

Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop

(2009) D. Pan et al.   RNA

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

(2009) Y.-G. Gao et al.   SCIENCE

Navigating the ribosome's metastable energy landscape

(2009) James B. Munro et al.   TRENDS IN BIOCHEMICAL SCIENCES

Spontaneous Intersubunit Rotation in Single Ribosomes

(2008) Peter V. Cornish et al.   MOLECULAR CELL

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS