BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 29, Pages 7629-7634
Publisher
Proceedings of the National Academy of Sciences
Online
2017-07-04
DOI
10.1073/pnas.1702453114
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Disordered clusters of Bak dimers rupture mitochondria during apoptosis
- (2017) Rachel T Uren et al. eLife
- Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
- (2016) R. Salvador-Gallego et al. EMBO JOURNAL
- Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis
- (2016) L. Grosse et al. EMBO JOURNAL
- Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains
- (2015) S Iyer et al. CELL DEATH AND DIFFERENTIATION
- BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes
- (2015) Z. Zhang et al. EMBO JOURNAL
- Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax and show no preference for Bak versus Bax
- (2015) C Hockings et al. Cell Death & Disease
- Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis
- (2015) Amber E. Alsop et al. Nature Communications
- Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
- (2015) Yamunadevi Subburaj et al. Nature Communications
- Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function
- (2014) S B Ma et al. CELL DEATH AND DIFFERENTIATION
- Differential retrotranslocation of mitochondrial Bax and Bak
- (2014) F. Todt et al. EMBO JOURNAL
- Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers
- (2014) Jason M. Brouwer et al. MOLECULAR CELL
- Structural Model of Active Bax at the Membrane
- (2014) Stephanie Bleicken et al. MOLECULAR CELL
- Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane
- (2014) Dana Westphal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
- (2013) Peter E. Czabotar et al. CELL
- Assembly of the Bak Apoptotic Pore
- (2013) Stephen Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Organization of the Mitochondrial Apoptotic BAK Pore
- (2013) Sreevidya Aluvila et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming
- (2013) Barbara Schellenberg et al. MOLECULAR CELL
- BID-induced structural changes in BAK promote apoptosis
- (2013) Tudor Moldoveanu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Direct activation of full-length proapoptotic BAK
- (2013) Elizaveta S. Leshchiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic Function
- (2012) Pedro Eitz Ferrer et al. PLoS One
- Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
- (2011) Frank Edlich et al. CELL
- Bax dimerizes via a symmetric BH3:groove interface during apoptosis
- (2011) G Dewson et al. CELL DEATH AND DIFFERENTIATION
- Bax Forms an Oligomer via Separate, Yet Interdependent, Surfaces
- (2010) Zhi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor
- (2010) Michael Lazarou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX
- (2010) Evripidis Gavathiotis et al. MOLECULAR CELL
- Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices
- (2009) Grant Dewson et al. MOLECULAR CELL
- Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis
- (2009) Hyungjin Kim et al. MOLECULAR CELL
- To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions
- (2008) Grant Dewson et al. MOLECULAR CELL
- BAX activation is initiated at a novel interaction site
- (2008) Evripidis Gavathiotis et al. NATURE
- Structure of transmembrane pore induced by Bax-derived peptide: Evidence for lipidic pores
- (2008) S. Qian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now