BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
出版年份 2017 全文链接
标题
BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 29, Pages 7629-7634
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-07-04
DOI
10.1073/pnas.1702453114
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Disordered clusters of Bak dimers rupture mitochondria during apoptosis
- (2017) Rachel T Uren et al. eLife
- Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
- (2016) R. Salvador-Gallego et al. EMBO JOURNAL
- Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis
- (2016) L. Grosse et al. EMBO JOURNAL
- Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains
- (2015) S Iyer et al. CELL DEATH AND DIFFERENTIATION
- BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes
- (2015) Z. Zhang et al. EMBO JOURNAL
- Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax and show no preference for Bak versus Bax
- (2015) C Hockings et al. Cell Death & Disease
- Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis
- (2015) Amber E. Alsop et al. Nature Communications
- Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
- (2015) Yamunadevi Subburaj et al. Nature Communications
- Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function
- (2014) S B Ma et al. CELL DEATH AND DIFFERENTIATION
- Differential retrotranslocation of mitochondrial Bax and Bak
- (2014) F. Todt et al. EMBO JOURNAL
- Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers
- (2014) Jason M. Brouwer et al. MOLECULAR CELL
- Structural Model of Active Bax at the Membrane
- (2014) Stephanie Bleicken et al. MOLECULAR CELL
- Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane
- (2014) Dana Westphal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
- (2013) Peter E. Czabotar et al. CELL
- Assembly of the Bak Apoptotic Pore
- (2013) Stephen Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Organization of the Mitochondrial Apoptotic BAK Pore
- (2013) Sreevidya Aluvila et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming
- (2013) Barbara Schellenberg et al. MOLECULAR CELL
- BID-induced structural changes in BAK promote apoptosis
- (2013) Tudor Moldoveanu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Direct activation of full-length proapoptotic BAK
- (2013) Elizaveta S. Leshchiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic Function
- (2012) Pedro Eitz Ferrer et al. PLoS One
- Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
- (2011) Frank Edlich et al. CELL
- Bax dimerizes via a symmetric BH3:groove interface during apoptosis
- (2011) G Dewson et al. CELL DEATH AND DIFFERENTIATION
- Bax Forms an Oligomer via Separate, Yet Interdependent, Surfaces
- (2010) Zhi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor
- (2010) Michael Lazarou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX
- (2010) Evripidis Gavathiotis et al. MOLECULAR CELL
- Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their α6 Helices
- (2009) Grant Dewson et al. MOLECULAR CELL
- Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis
- (2009) Hyungjin Kim et al. MOLECULAR CELL
- To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions
- (2008) Grant Dewson et al. MOLECULAR CELL
- BAX activation is initiated at a novel interaction site
- (2008) Evripidis Gavathiotis et al. NATURE
- Structure of transmembrane pore induced by Bax-derived peptide: Evidence for lipidic pores
- (2008) S. Qian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More