Crystal structures of ternary complexes of archaeal B-family DNA polymerases

Design and synthesis of fluorescence-labeled nucleotide with a cleavable azo linker for DNA sequencing

(2016) Lianjiang Tan et al.   CHEMICAL COMMUNICATIONS

A fidelity mechanism in DNA polymerase lambda promotes error‐free bypass of 8‐oxo‐dG

(2016) Matthew J Burak et al.   EMBO JOURNAL

Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array

(2016) Carl W. Fuller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new paradigm of DNA synthesis: three-metal-ion catalysis

(2016) Wei Yang et al.   Cell and Bioscience

Fast, Efficient, and Stable Conjugation of Multiple DNA Strands on Colloidal Quantum Dots

(2015) Anusuya Banerjee et al.   BIOCONJUGATE CHEMISTRY

Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases

(2015) Michaela Mačková et al.   CHEMBIOCHEM

DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme

(2015) D. Verga et al.   CHEMICAL COMMUNICATIONS

Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography

(2015) Rajan Vyas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions

(2015) Jana Balintová et al.   Chemical Science

Enzymatic incorporation and fluorescent labelling of cyclooctyne-modified deoxyuridine triphosphates in DNA

(2014) Xiaomei Ren et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels–Alder reaction

(2014) Holger Bußkamp et al.   CHEMICAL COMMUNICATIONS

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide

(2014) Bret D. Freudenthal et al.   NATURE

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex

(2013) Konrad Bergen et al.   CHEMBIOCHEM

Why Are There So Many Diverse Replication Machineries?

(2013) Patrick Forterre   JOURNAL OF MOLECULAR BIOLOGY

Snapshot of a DNA Polymerase while Incorporating Two Consecutive C5-Modified Nucleotides

(2013) Samra Obeid et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ

(2013) Matthew Hogg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA

(2013) Samantha A. Wynne et al.   PLoS One

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

(2013) Rajika L Perera et al.   eLife

Interactions of non-polar and “Click-able” nucleotides in the confines of a DNA polymerase active site

(2012) Samra Obeid et al.   CHEMICAL COMMUNICATIONS

Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates

(2012) Konrad Bergen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE

Barcoded Nucleotides

(2011) Anna Baccaro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unlocking the Sugar “Steric Gate” of DNA Polymerases

(2011) Jessica A. Brown et al.   BIOCHEMISTRY

C5-Functionalized DNA, LNA, and α-L-LNA: Positional Control of Polarity-Sensitive Fluorophores Leads to Improved SNP-Typing

(2011) Michael E. Østergaard et al.   CHEMISTRY-A EUROPEAN JOURNAL

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Insights into Base Selectivity from the 1.8 Å Resolution Structure of an RB69 DNA Polymerase Ternary Complex

(2010) Mina Wang et al.   BIOCHEMISTRY

Replication through an abasic DNA lesion: structural basis for adenine selectivity

(2010) Samra Obeid et al.   EMBO JOURNAL

3V: cavity, channel and cleft volume calculator and extractor

(2010) N. R. Voss et al.   NUCLEIC ACIDS RESEARCH

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase

(2010) S. Obeid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Insight into Translesion Synthesis by DNA Pol II

(2009) Feng Wang et al.   CELL

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ

(2009) Michael K Swan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nucleic acid polymerases use a general acid for nucleotidyl transfer

(2009) Christian Castro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Web 3DNA--a web server for the analysis, reconstruction, and visualization of three-dimensional nucleic-acid structures

(2009) G. Zheng et al.   NUCLEIC ACIDS RESEARCH

Synthesis and enzymatic incorporation of modified deoxyuridine triphosphates

(2009) Vinciane Borsenberger et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE

Four-color DNA sequencing with 3'-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides

(2008) J. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA