A new paradigm of DNA synthesis: three-metal-ion catalysis

Capture of a third Mg2+ is essential for catalyzing DNA synthesis

(2016) Y. Gao et al.   SCIENCE

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2′-deoxyguanosine

(2015) Yan Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How DNA Polymerases Catalyze DNA Replication, Repair, and Mutation

(2014) Ming-Daw Tsai   BIOCHEMISTRY

Recent Insight into the Kinetic Mechanisms and Conformational Dynamics of Y-Family DNA Polymerases

(2014) Brian A. Maxwell et al.   BIOCHEMISTRY

RB69 DNA Polymerase Structure, Kinetics, and Fidelity

(2014) Shuangluo Xia et al.   BIOCHEMISTRY

An Overview of Y-Family DNA Polymerases and a Case Study of Human DNA Polymerase η

(2014) Wei Yang   BIOCHEMISTRY

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide

(2014) Bret D. Freudenthal et al.   NATURE

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

Mechanism of somatic hypermutation at the WA motif by human DNA polymerase  

(2013) Y. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE

Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion

(2012) Lee Lior-Hoffmann et al.   NUCLEIC ACIDS RESEARCH

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Polymerase-Tailored Variations in the Water-Mediated and Substrate-Assisted Mechanism for Nucleotidyl Transfer: Insights from a Study of T7 DNA Polymerase

(2009) Lihua Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of Induced Fit in Enzyme Specificity: A Molecular Forward/Reverse Switch

(2008) Kenneth A. Johnson   JOURNAL OF BIOLOGICAL CHEMISTRY

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE