Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex

Interactions of non-polar and “Click-able” nucleotides in the confines of a DNA polymerase active site

(2012) Samra Obeid et al.   CHEMICAL COMMUNICATIONS

Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase

(2012) Jérôme Gouge et al.   JOURNAL OF MOLECULAR BIOLOGY

Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates

(2012) Konrad Bergen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

(2012) Karin Betz et al.   Nature Chemical Biology

Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases

(2011) Pavel Kielkowski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Barcoded Nucleotides

(2011) Anna Baccaro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structures of DNA Polymerases Caught Processing Size-Augmented Nucleotide Probes

(2010) Karin Betz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues

(2010) Tom Killelea et al.   BIOCHEMISTRY

Engineered DNA Polymerases in Biotechnology

(2010) Ramon Kranaster  et al.   CHEMBIOCHEM

Replication through an abasic DNA lesion: structural basis for adenine selectivity

(2010) Samra Obeid et al.   EMBO JOURNAL

Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA

(2010) Satu Ikonen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase

(2010) S. Obeid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Chemical Biology of Aptamers

(2009) Günter Mayer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase

(2009) Rakesh N. Veedu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enzymatic Synthesis of Multiple Spin-Labeled DNA

(2008) Samra Obeid et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Postsynthetic DNA Modification through the Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction

(2008) Philipp M. E. Gramlich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel strategies for the site-specific covalent labelling of nucleic acids

(2008) Samuel H. Weisbrod et al.   CHEMICAL COMMUNICATIONS

Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus

(2008) Suhng Wook Kim et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography

(2008) Susan J. Firbank et al.   JOURNAL OF MOLECULAR BIOLOGY

Opposed Steric Constraints in Human DNA Polymerase β andE. coliDNA Polymerase I

(2008) Francesca Di Pasquale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polymerase Chain Reaction and Transcription Using Locked Nucleic Acid Nucleotide Triphosphates

(2008) Rakesh N. Veedu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE

Cross-coupling reactions of nucleoside triphosphates followed by polymerase incorporation. Construction and applications of base-functionalized nucleic acids

(2008) Michal Hocek et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Single-Molecule DNA Sequencing of a Viral Genome

(2008) T. D. Harris et al.   SCIENCE