Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis
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Title
Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis
Authors
Keywords
Fibrosis, Gastrointestinal tract, Mouse models, Colon, Colitis, Fibroblasts, Collagens, Immunohistochemical analysis
Journal
PLoS One
Volume 12, Issue 2, Pages e0171093
Publisher
Public Library of Science (PLoS)
Online
2017-02-17
DOI
10.1371/journal.pone.0171093
References
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Note: Only part of the references are listed.- Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis
- (2016) Silvia Speca et al. INFLAMMATORY BOWEL DISEASES
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- (2015) Hua-Yu Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2015) S. P. Singh et al. Disease Models & Mechanisms
- Fibrosis — A Common Pathway to Organ Injury and Failure
- (2015) Don C. Rockey et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Role of PPAR Gamma in Systemic Sclerosis
- (2015) Andréa Tavares Dantas et al. PPAR Research
- Inhibitory Effects of PPARγ Ligands on TGF-β1–Induced Corneal Myofibroblast Transformation
- (2014) Kye-Im Jeon et al. AMERICAN JOURNAL OF PATHOLOGY
- Akt2 Mediates TGF-�1-Induced Epithelial to Mesenchymal Transition by Deactivating GSK3�/Snail Signaling Pathway in Renal Tubular Epithelial Cells
- (2014) Aiping Lan et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- PPAR-γ inhibits IL-13-induced collagen production in mouse airway fibroblasts
- (2014) Jiamei Lu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- ECM remodelling in IBD: innocent bystander or partner in crime? The emerging role of extracellular molecular events in sustaining intestinal inflammation
- (2014) Elee Shimshoni et al. GUT
- Mechanisms of initiation and progression of intestinal fibrosis in IBD
- (2014) Giovanni Latella et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Wnt signaling in liver fibrosis: Progress, challenges and potential directions
- (2013) Cheng-gui Miao et al. BIOCHIMIE
- Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor γ
- (2013) Yong-ho Lee et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PPAR-Gamma in Ulcerative Colitis: A Novel Target for Intervention
- (2013) Benjamin Bertin et al. CURRENT DRUG TARGETS
- Mechanisms of Tissue Remodeling in Inflammatory Bowel Disease
- (2013) Florian Rieder et al. DIGESTIVE DISEASES
- Nanomedicines of Hedgehog Inhibitor and PPAR-γ Agonist for Treating Liver Fibrosis
- (2013) Virender Kumar et al. PHARMACEUTICAL RESEARCH
- Combination of a peroxisome proliferator-activated receptor-gamma agonist and an angiotensin II receptor blocker attenuates myocardial fibrosis and dysfunction in type 2 diabetic rats
- (2013) Chi Young Shim et al. Journal of Diabetes Investigation
- SB216763, a selective small molecule inhibitor of glycogen synthase kinase-3, improves bleomycin-induced pulmonary fibrosis via activating autophagy
- (2013) Hong Liu et al. Acta Pharmaceutica Sinica B
- Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells
- (2012) Jun Wei et al. ARTHRITIS AND RHEUMATISM
- The Impact of Matrix Metalloproteinases and Their Tissue Inhibitors in Inflammatory Bowel Diseases
- (2012) Gábor Lakatos et al. DIGESTIVE DISEASES
- Interactions Between β-Catenin and Transforming Growth Factor-β Signaling Pathways Mediate Epithelial-Mesenchymal Transition and Are Dependent on the Transcriptional Co-activator cAMP-response Element-binding Protein (CREB)-binding Protein (CBP)
- (2012) Beiyun Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proinflammatory cytokines induce crosstalk between colonic epithelial cells and subepithelial myofibroblasts: Implication in intestinal fibrosis
- (2012) Ioannis Drygiannakis et al. Journal of Crohns & Colitis
- Targeting Peroxisome Proliferator-Activated Receptors (PPARs): Development of Modulators
- (2012) Céline Pirat et al. JOURNAL OF MEDICINAL CHEMISTRY
- The improving effects on hepatic fibrosis of interferon-γ liposomes targeted to hepatic stellate cells
- (2012) Qinghua Li et al. NANOTECHNOLOGY
- Mechanisms of fibrosis: therapeutic translation for fibrotic disease
- (2012) Thomas A Wynn et al. NATURE MEDICINE
- β-Catenin pathway is required for TGF-β1 inhibition of PPARγ expression in cultured hepatic stellate cells
- (2012) Jingjing Qian et al. PHARMACOLOGICAL RESEARCH
- β-Catenin Loss in Hepatocytes Promotes Hepatocellular Cancer after Diethylnitrosamine and Phenobarbital Administration to Mice
- (2012) Prince Kwaku Awuah et al. PLoS One
- Cellular and molecular mechanisms of intestinal fibrosis
- (2012) Silvia Speca WORLD JOURNAL OF GASTROENTEROLOGY
- Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
- (2012) Alfiya Akhmetshina et al. Nature Communications
- Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders
- (2011) Sonsoles Piera-Velazquez et al. AMERICAN JOURNAL OF PATHOLOGY
- Inflammation-Induced Endothelial-to-Mesenchymal Transition
- (2011) Florian Rieder et al. AMERICAN JOURNAL OF PATHOLOGY
- Themes in fibrosis and gastrointestinal inflammation
- (2011) Claudio Fiocchi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Results of the 2nd Scientific Workshop of the ECCO (III): Basic mechanisms of intestinal healing
- (2011) Florian Rieder et al. Journal of Crohns & Colitis
- Wnt/β-catenin pathway forms a negative feedback loop during TGF-β1 induced human normal skin fibroblast-to-myofibroblast transition
- (2011) Jiaqi Liu et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Anti-inflammatory Effects of Thiazolidinediones in Human Airway Smooth Muscle Cells
- (2010) Ming Zhu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Identification of Epithelial to Mesenchymal Transition as a Novel Source of Fibroblasts in Intestinal Fibrosis
- (2010) Sarah N. Flier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
- (2010) W. R. Henderson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-β1 in Renal Tubular Epithelial Cells
- (2009) Guoping Zheng et al. AMERICAN JOURNAL OF PATHOLOGY
- P-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation
- (2009) K. Bauer et al. CARCINOGENESIS
- Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-inducedcolorectal fibrosis
- (2009) G. Latella et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
- (2009) Asish K. Ghosh et al. FASEB JOURNAL
- Cloning of the HumanGLI2Promoter
- (2009) Sylviane Dennler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
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