Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice

Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia

(2016) Gautam Rishi et al.   AMERICAN JOURNAL OF HEMATOLOGY

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice

(2016) A. Nai et al.   BLOOD

Hepcidin independent iron recycling in a mouse model of β-thalassaemia intermedia

(2016) David M. Frazer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Iron Deficiency Anemia

(2016) Sant-Rayn Pasricha et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats

(2016) Jana Frýdlová et al.   PLoS One

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

(2015) Felix Jäckle et al.   BIOCHEMICAL JOURNAL

Cell surface serine protease matriptase-2 suppresses fetuin-A/AHSG-mediated induction of hepcidin

(2015) Marit Stirnberg et al.   BIOLOGICAL CHEMISTRY

New insights into iron regulation and erythropoiesis

(2015) Airie Kim et al.   CURRENT OPINION IN HEMATOLOGY

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

(2015) A. Pagani et al.   HAEMATOLOGICA

Identification of TMPRSS6 cleavage sites of hemojuvelin

(2015) Marco Rausa et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Stress-associated erythropoiesis initiation is regulated by type 1 conventional dendritic cells

(2015) Taeg S. Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein

(2015) Eleanor G Healey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein

(2015) Eleanor G Healey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

(2015) A. Pagani et al.   HAEMATOLOGICA

The second transferrin receptor regulates red blood cell production in mice

(2014) A. Nai et al.   BLOOD

Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis

(2014) A. Willemetz et al.   BLOOD

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

(2014) Daniel F. Wallace et al.   BRITISH JOURNAL OF HAEMATOLOGY

Identification of erythroferrone as an erythroid regulator of iron metabolism

(2014) Léon Kautz et al.   NATURE GENETICS

Administration of recombinant erythropoietin alone does not improve the phenotype in iron refractory iron deficiency anemia patients

(2012) Kai Lehmberg et al.   ANNALS OF HEMATOLOGY

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of  -thalassemia

(2012) A. Nai et al.   BLOOD

Myonectin (CTRP15), a Novel Myokine That Links Skeletal Muscle to Systemic Lipid Homeostasis

(2012) Marcus M. Seldin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is EPO therapy able to correct iron deficiency anaemia caused by matriptase-2 deficiency?

(2011) Gaël Nicolas et al.   BRITISH JOURNAL OF HAEMATOLOGY

Stress erythropoiesis: new signals and new stress progenitor cells

(2011) Robert F Paulson et al.   CURRENT OPINION IN HEMATOLOGY

Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis

(2010) H. Forejtnikova et al.   BLOOD

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis

(2010) K. E. Finberg et al.   BLOOD

Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice

(2010) J. Gao et al.   BLOOD

EPO-mediated reduction in Hamp expression in vivo corrects iron deficiency anaemia in TMPRSS6 deficiency

(2010) Hongfan Peng et al.   BRITISH JOURNAL OF HAEMATOLOGY

Soluble Repulsive Guidance Molecule c/Hemojuvelin Is a Broad Spectrum Bone Morphogenetic Protein (BMP) Antagonist and Inhibits both BMP2- and BMP6-mediated Signaling and Gene Expression

(2010) Mahta Nili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

(2008) F. Guillem et al.   BLOOD

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

(2008) M. A. Melis et al.   HAEMATOLOGICA

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE