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Title
Identification of TMPRSS6 cleavage sites of hemojuvelin
Authors
Keywords
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Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Volume 19, Issue 4, Pages 879-888
Publisher
Wiley
Online
2015-02-22
DOI
10.1111/jcmm.12462
References
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Related references
Note: Only part of the references are listed.- Proteomic analysis and molecular modelling characterize the iron-regulatory protein haemojuvelin/repulsive guidance molecule c
- (2013) Mahta Nili et al. BIOCHEMICAL JOURNAL
- How to Assess Causality ofTMPRSS6Mutations?
- (2013) Laura Silvestri et al. HUMAN MUTATION
- Structure of the Repulsive Guidance Molecule (RGM)-Neogenin Signaling Hub
- (2013) C. H. Bell et al. SCIENCE
- Neogenin Interacts with Matriptase-2 to Facilitate Hemojuvelin Cleavage
- (2012) Caroline A. Enns et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
- (2011) A. U. Steinbicker et al. BLOOD
- Soluble Repulsive Guidance Molecule c/Hemojuvelin Is a Broad Spectrum Bone Morphogenetic Protein (BMP) Antagonist and Inhibits both BMP2- and BMP6-mediated Signaling and Gene Expression
- (2010) Mahta Nili et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Matriptase-2- and Proprotein Convertase-cleaved Forms of Hemojuvelin Have Different Roles in the Down-regulation of Hepcidin Expression
- (2010) Julia E. Maxson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- I-TASSER: a unified platform for automated protein structure and function prediction
- (2010) Ambrish Roy et al. Nature Protocols
- Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia
- (2009) L. Silvestri et al. BLOOD
- BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
- (2009) Billy Andriopoulos Jr et al. NATURE GENETICS
- Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin
- (2008) Robin Kuns-Hashimoto et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
- (2008) A. R. Folgueras et al. BLOOD
- Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
- (2008) Y. Xia et al. BLOOD
- Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin
- (2008) David Kuninger et al. BMC BIOCHEMISTRY
- The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin
- (2008) Laura Silvestri et al. Cell Metabolism
- Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response
- (2008) A. Pagani et al. HAEMATOLOGICA
- Neogenin-mediated Hemojuvelin Shedding Occurs after Hemojuvelin Traffics to the Plasma Membrane
- (2008) An-Sheng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
- (2008) Karin E Finberg et al. NATURE GENETICS
- The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
- (2008) X. Du et al. SCIENCE
- Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis
- (2007) L. Silvestri et al. BLOOD
- Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site
- (2007) Lan Lin et al. BLOOD CELLS MOLECULES AND DISEASES
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