Power of protein/tRNA functional assembly against aberrant aggregation

Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain

(2017) Petar Stefanov Kovachev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flavin-Dependent Methylation of RNAs: Complex Chemistry for a Simple Modification

(2016) Djemel Hamdane et al.   JOURNAL OF MOLECULAR BIOLOGY

Do nucleic acids moonlight as molecular chaperones?

(2016) Brianne E. Docter et al.   NUCLEIC ACIDS RESEARCH

A chemical chaperone induces inhomogeneous conformational changes in flexible proteins

(2016) Djemel Hamdane et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Glycerol inhibits the primary pathways and transforms the secondary pathway of insulin aggregation

(2016) Shivnetra Saha et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

RNA modification enzyme TruB is a tRNA chaperone

(2016) Laura Carole Keffer-Wilkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flavin–Protein Complexes: Aromatic Stacking Assisted by a Hydrogen Bond

(2015) Djemel Hamdane et al.   BIOCHEMISTRY

Layers of structure and function in protein aggregation

(2015) Motomasa Tanaka et al.   Nature Chemical Biology

Salt mediated unusual switching in the aggregation kinetic profile of human carbonic anhydrase

(2015) Preeti Gupta et al.   RSC Advances

Switch in the Aggregation Pathway of Bovine Serum Albumin Mediated by Electrostatic Interactions

(2014) Shivnetra Saha et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Energy landscapes of functional proteins are inherently risky

(2014) Anne Gershenson et al.   Nature Chemical Biology

PASTA 2.0: an improved server for protein aggregation prediction

(2014) Ian Walsh et al.   NUCLEIC ACIDS RESEARCH

Irreversible Denaturation of Maltodextrin Glucosidase Studied by Differential Scanning Calorimetry, Circular Dichroism, and Turbidity Measurements

(2014) Megha Goyal et al.   PLoS One

In the Multi-domain Protein Adenylate Kinase, Domain Insertion Facilitates Cooperative Folding while Accommodating Function at Domain Interfaces

(2014) V. V. Hemanth Giri Rao et al.   PLoS Computational Biology

Activation of a Unique Flavin-Dependent tRNA-Methylating Agent

(2013) Djemel Hamdane et al.   BIOCHEMISTRY

Posttranscriptional RNA Modifications: Playing Metabolic Games in a Cell’s Chemical Legoland

(2013) Mark Helm et al.   CHEMISTRY & BIOLOGY

The tRNA Recognition Mechanism of Folate/FAD-dependent tRNA Methyltransferase (TrmFO)

(2012) Ryota Yamagami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FAD/Folate-Dependent tRNA Methyltransferase: Flavin as a New Methyl-Transfer Agent

(2012) Djemel Hamdane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of an Intermediate State in Protein Folding and Aggregation

(2012) P. Neudecker et al.   SCIENCE

A Catalytic Intermediate and Several Flavin Redox States Stabilized by Folate-Dependent tRNA Methyltransferase fromBacillus subtilis

(2011) Djemel Hamdane et al.   BIOCHEMISTRY

Insights into Folate/FAD-dependent tRNA Methyltransferase Mechanism

(2011) Djemel Hamdane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ribosome Modulates Nascent Protein Folding

(2011) C. M. Kaiser et al.   SCIENCE

The folding cooperativity of a protein is controlled by its chain topology

(2010) Elizabeth A. Shank et al.   NATURE

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

RNA-mediated chaperone type for de novo protein folding

(2010) Seong Il Choi et al.   RNA Biology

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase

(2009) H. Nishimasu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Between-Species Variation in the Kinetic Stability of TIM Proteins Linked to Solvation-Barrier Free Energies

(2008) Miguel Costas et al.   JOURNAL OF MOLECULAR BIOLOGY

Amyloid formation by globular proteins under native conditions

(2008) Fabrizio Chiti et al.   Nature Chemical Biology

Folding versus aggregation: Polypeptide conformations on competing pathways

(2007) Thomas R. Jahn et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS