Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy

MCPIP1 Regulates Alveolar Macrophage Apoptosis and Pulmonary Fibroblast Activation Afterin vitroExposure to Silica

(2016) Xingang Wang et al.   TOXICOLOGICAL SCIENCES

Neogambogic acid prevents silica-induced fibrosis via inhibition of high-mobility group box 1 and MCP-1-induced protein 1

(2016) Wei Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Autophagy is essential for ultrafine particle-induced inflammation and mucus hyperproduction in airway epithelium

(2015) Zhi-Hua Chen et al.   Autophagy

The Role of MCPIP1 in Ischemia/Reperfusion Injury-Induced HUVEC Migration and Apoptosis

(2015) Tiebing Zhu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Co-localization of iron binding on silica with p62/sequestosome1 (SQSTM1) in lung granulomas of mice with acute silicosis

(2015) Yasuo Shimizu et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

MCPIP1 Regulates Fibroblast Migration in 3-D Collagen Matrices Downstream of MAP Kinases and NF-κB

(2015) Jie Chao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis

(2015) Xueting Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis

(2015) Wei Wang et al.   Scientific Reports

Type I Interferon Inhibition of MicroRNA-146a Maturation Through Up-Regulation of Monocyte Chemotactic Protein-Induced Protein 1 in Systemic Lupus Erythematosus

(2015) Bo Qu et al.   Arthritis & Rheumatology

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

(2014) Meghan B. Azad et al.   Autophagy

TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwart Silica-Induced Pulmonary Fibrosis

(2014) F. Fazzi et al.   JOURNAL OF IMMUNOLOGY

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression of green fluorescent protein in human foreskin fibroblasts for use in 2D and 3D culture models

(2014) Jie Chao et al.   WOUND REPAIR AND REGENERATION

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

Targeted disruption of MCPIP1/Zc3h12a results in fatal inflammatory disease

(2013) Ruidong Miao et al.   IMMUNOLOGY AND CELL BIOLOGY

Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages

(2013) Bin Wan et al.   TOXICOLOGY LETTERS

Insufficient autophagy in idiopathic pulmonary fibrosis

(2012) Jun Araya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy

(2012) Arpita Roy et al.   CELLULAR SIGNALLING

Th2-Associated Alternative Kupffer Cell Activation Promotes Liver Fibrosis without Inducing Local Inflammation

(2012) Giuliana López-Navarrete et al.   International Journal of Biological Sciences

Silicosis

(2012) Chi Chiu Leung et al.   LANCET

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Autophagy

(2011) Jeffrey A. Haspel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Silica nanoconstruct cellular toleration threshold in vitro

(2011) Heather L. Herd et al.   JOURNAL OF CONTROLLED RELEASE

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Osteoclast precursor differentiation by MCPIP via oxidative stress, endoplasmic reticulum stress, and autophagy

(2011) Kangkai Wang et al.   Journal of Molecular Cell Biology

Autophagic Protein LC3B Confers Resistance against Hypoxia-induced Pulmonary Hypertension

(2010) Seon-Jin Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer

(2010) Kevin Dalby et al.   Autophagy

Hyperglycaemia-induced cardiomyocyte death is mediated via MCP-1 production and induction of a novel zinc-finger protein MCPIP

(2010) Craig W. Younce et al.   CARDIOVASCULAR RESEARCH

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling

(2010) Jian Liang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

(2010) Alessandro Luciani et al.   NATURE CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP

(2009) Craig W. Younce et al.   BIOCHEMICAL JOURNAL

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

MCP-1 (Monocyte Chemotactic Protein-1)-induced Protein, a Recently Identified Zinc Finger Protein, Induces Adipogenesis in 3T3-L1 Pre-adipocytes without Peroxisome Proliferator-activated Receptor γ

(2009) Craig W. Younce et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockdown of integrin β4-induced autophagic cell death associated with P53 in A549 lung adenocarcinoma cells

(2008) Qiuxia He et al.   FEBS Journal

Silica binding and toxicity in alveolar macrophages

(2007) Raymond F. Hamilton et al.   FREE RADICAL BIOLOGY AND MEDICINE