A review on metronidazole: an old warhorse in antimicrobial chemotherapy
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Title
A review on metronidazole: an old warhorse in antimicrobial chemotherapy
Authors
Keywords
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Journal
PARASITOLOGY
Volume -, Issue -, Pages 1-12
Publisher
Cambridge University Press (CUP)
Online
2017-11-23
DOI
10.1017/s0031182017002025
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- Two Multidrug-Resistant Clinical Isolates of Bacteroides fragilis Carry a Novel Metronidazole ResistancenimGene (nimJ)
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- (2010) Linda A. Dunn et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
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