Article
Oncology
Kathleen Iles, Paula D. Strassle, Chris B. Agala, Julia Button, Stephanie Downs-Canner
Summary: The study found that over 30% of breast cancer patients underwent surgical axillary staging before receiving neoadjuvant chemotherapy, resulting in a higher rate of subsequent axillary lymph node dissection in this cohort. Preoperative staging was significantly associated with younger age, higher clinical T stage, lobular subtype, higher grade, and HR+/HER2- subtype. Women who underwent preoperative axillary staging were more likely to undergo axillary lymph node dissection.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Alessia Candellone, Vittorio Saettone, Paola Badino, Flavia Girolami, Elisabetta Radice, Domenico Bergero, Rosangela Odore, Giorgia Meineri
Summary: Feline hyperthyroidism is considered a spontaneous animal model for human thyrotoxicosis, with many shared features in pathogenesis, clinical signs, and treatment options. Methimazole is the first-choice drug, but it can have side effects, and dietary antioxidant supplementation may help mitigate oxidative burden.
Editorial Material
Cell Biology
Joseph E. Aslan
Summary: Proteomics tools have greatly contributed to our understanding of platelet biology, with the ability to identify, detect, and quantify protein-related details. The platelet proteome is composed of thousands of different proteins, and changes in this proteome can affect platelet function in health and disease. Challenges still remain in conducting, validating, and interpreting platelet proteomics experiments, but future studies using advanced proteomics technologies may shed more light on platelet-mediated mechanisms in human health and disease.
Article
Cardiac & Cardiovascular Systems
Shelley A. Hall, Hannah Copeland, Amit Alam, Susan M. Joseph
Summary: Right heart failure is a common complication following left ventricular assist device implantation, and its definition has continuously evolved to better identify this complex pathology. The latest definition proposed in 2020 will enhance our recognition and understanding of this complex disease phenomenon.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Geochemistry & Geophysics
Uwe Ring, Johannes Glodny, Andreas Scharf, Reuben Hansman
Summary: This study reveals the existence of two subduction zones in the NE margin of Arabia in the Oman Mountains during the mid-Cretaceous, using Rb-Sr geochronology. This finding has important implications for the formation of the Samail Ophiolite and its metamorphic sole, as well as the tectonic evolution of the Saih Hatat window.
Article
Environmental Sciences
Maria Elena Crespo-Lopez, Marcus Augusto-Oliveira, Amanda Lopes-Araujo, Leticia Santos-Sacramento, Priscila Yuki Takeda, Barbarella de Matos Macchi, Jose Luiz Martins do Nascimento, Cristiane S. F. Maia, Rafael R. Lima, Gabriela P. Arrifano
Summary: Mercury is among the top ten most dangerous chemicals for public health worldwide, with increasing emissions particularly in South America, notably the Amazon region. Human populations in this area are highly exposed to methylmercury through contaminated fish consumption, with levels far exceeding those of other regions globally.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Oncology
Ana Carolina Rathsam Leite, Daniele Assad Suzuki, Allan Anderson Lima Pereira, Natalia Polidorio Machado, Romualdo Barroso-Sousa, Tatiana Strava Correa, Fernanda Cesar Moura, Igor Alexandre Protzner Morbeck, Brenda Pires Gumz, Luiza Dib Batista Bugiato Faria, Gustavo dos Santos Fernandes, Renata Lazari Sandoval
Summary: This study highlights the importance of identifying individuals at higher risk of developing cancer through genetic testing approaches, with international guidelines for genetic testing proving to be more effective than Brazilian national standards. Lack of access may lead to some potential carriers not being identified.
FRONTIERS IN ONCOLOGY
(2022)
Article
Information Science & Library Science
Jie Meng
Summary: This research investigates the impact and management strategies of extreme voices on public opinions. The findings indicate that opinion divergence can occur in any preference-held audience and information noise can moderate the valence of opinions. Additionally, the halo effect on information sources amplifies voices. The study highlights the importance of understanding public opinion evolution and improving communication effects.
TELEMATICS AND INFORMATICS
(2022)
Editorial Material
Urology & Nephrology
Federica Piani, Richard J. Johnson
Summary: Gout is common in patients with CKD, and those with kidney dysfunction may have hyperechoic medullas, potentially linked to increased risk of hypertension and kidney dysfunction. More research is needed to validate these findings.
KIDNEY INTERNATIONAL
(2021)
Article
Computer Science, Hardware & Architecture
Nischal Shrestha, Colton Botta, Titus Barik, Chris Parnin
Summary: Programmers may face difficulties in learning new programming languages, especially when previous knowledge interferes with the learning process. Research has shown that programmers often make unsuccessful attempts to relate a new programming language to what they already know.
COMMUNICATIONS OF THE ACM
(2022)
Article
Ecology
Hynek Burda
Summary: This article provides an overview of over three decades of research on Zambian mole-rats, highlighting unanswered questions and untested hypotheses, and proposing approaches to address them. The research proposals cover various aspects such as sensory ecology, population dynamics, communication, genetics, and family structure.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2022)
Article
Biochemistry & Molecular Biology
Stephanie Best, Janet C. Long, Zoe Fehlberg, Tahlia Theodorou, Sarah Hatem, Alison Archibald, Jeffrey Braithwaite
Summary: Recent advances in genomic sequencing have made reproductive genetic carrier screening (RGCS) more accessible. Non-genetic health care professionals are increasingly offering RGCS to consumers. A qualitative interview study was conducted to identify influences on health care professionals offering RGCS through the Australian research study, Mackenzie's Mission. Barriers and enabling factors were identified and categorized across three target behaviors: engaging with RGCS, identifying eligible patients, and offering RGCS. Understanding the drivers of current health care professionals' behavior can help improve service delivery.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2023)
Article
Ecology
Istvan Dunkl, Nicole Lovenduski, Alessio Collalti, Vivek K. Arora, Tatiana Ilyina, Victor Brovkin
Summary: The predictability of atmospheric CO2 concentrations is limited by the high variability in terrestrial gross primary productivity (GPP), with uncertainties in the drivers of this variability among Earth system models (ESMs). This study evaluates the impact of these uncertainties on CO2 predictability in six ESMs, finding that the patterns of GPP variability and its predictability are influenced by different environmental drivers depending on the ESM. There is potential for improving CO2 predictability by reducing uncertainties in GPP sensitivity to soil moisture and improving observational products for GPP variability.
Article
Engineering, Environmental
Hina Habib, Michelle Wagner, Cornelis Peter Balde, Lucia Herreras Martinez, Jaco Huisman, Jo Dewulf
Summary: This study develops a quantitative model to describe the flows of Waste Electrical and Electronic Equipment (WEEE) in European Union (EU) Member States, Great Britain, Norway, and Switzerland in 2018. The results show that a significant amount of WEEE was not properly collected and recycled, highlighting the need for improved waste management targets.
RESOURCES CONSERVATION AND RECYCLING
(2022)
Article
Hospitality, Leisure, Sport & Tourism
Junya Liu, Suiwen (Sharon) Zou, Jamie M. Chen
Summary: This study examines the relationship between government funding, attraction characteristics, and local economic conditions for 262 public attractions in China from 2015 to 2018. The findings suggest that attraction characteristics are associated with the amount of government appropriations, but have a smaller impact on the likelihood of receiving funding. As the government funding level increases, the type and quality of attractions have a stronger influence, while other characteristics have a weaker influence. The local economic condition is a significant factor in the amount of government funding.
JOURNAL OF TRAVEL RESEARCH
(2023)
Article
Microbiology
Victoria E. Watson, Megan E. Jacob, James R. Flowers, Sandra J. Strong, Chitrita DebRoy, Jody L. Gookin
JOURNAL OF CLINICAL MICROBIOLOGY
(2017)
Article
Multidisciplinary Sciences
Jody L. Gookin, Kyle G. Mathews, John Cullen, Gabriela Seiler
Article
Veterinary Sciences
Sandra J. Strong, Jody L. Gookin, Maria T. Correa, Ron E. Banks
JOURNAL OF FELINE MEDICINE AND SURGERY
(2020)
Article
Multidisciplinary Sciences
Kathleen M. Aicher, John M. Cullen, Gabriela S. Seiler, Katharine F. Lunn, Kyle G. Mathews, Jody L. Gookin
Article
Microbiology
Victoria E. Watson, Megan E. Jacob, Jose M. Bruno-Barcena, Sophia Amirsultan, Stephen H. Stauffer, Victoria O. Piqueras, Rafael Frias, Jody L. Gookin
VETERINARY MICROBIOLOGY
(2019)
Article
Parasitology
Rachel Dickson, Julie Vose, David Bemis, Maggie Daves, Thomas Cecere, Jody L. Gookin, Joerg Steiner, M. Katherine Tolbert
VETERINARY PARASITOLOGY
(2019)
Article
Veterinary Sciences
Adam J. Birkenheuer, Kenneth D. Royal, Anthony Cerreta, Daniel Hemstreet, Katharine F. Lunn, Jody L. Gookin, Stephanie McGarvey
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2020)
Article
Veterinary Sciences
Barry A. Hedgespeth, Stephen H. Stauffer, James B. Robertson, Jody L. Gookin
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2020)
Article
Immunology
Victoria E. Watson, Tracy H. Hazen, David A. Rasko, Megan E. Jacob, Johanna R. Elfenbein, Stephen H. Stauffer, Jody L. Gookin
Summary: This study identified kittens as hosts for aEPEC and analyzed the genomic similarity between kitten aEPEC and human aEPEC isolates, showing no significant differences. The study also found that aEPEC isolated from kittens exhibit similar adherence patterns and ability to aggregate actin in cells as human aEPEC, with the motility appearing to be an important factor in the pathogenesis of lethal infection associated with aEPEC in kittens. Kittens may be a reservoir for aEPEC indistinguishable from human strains, providing a potential comparative animal model for aEPEC pathogenesis research.
INFECTION AND IMMUNITY
(2021)
Article
Veterinary Sciences
Crystal Lindaberry, Shelly Vaden, Kathleen M. Aicher, Gabriela Seiler, James Robertson, Rachel Cianciolo, Ching Yang, Jody L. Gookin
Summary: This study found a significant association between gallbladder mucocele formation and proteinuria in dogs, with the severity of proteinuria increasing in relation to the severity of illness. Treatment of proteinuria in dogs with mucocele formation may help reduce long-term kidney morbidity.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Metzere Bierlein, Barry A. Hedgespeth, M. Andrea Azcarate-Peril, Stephen H. Stauffer, Jody L. Gookin
Summary: The study aimed to characterize differences in fecal microbiota of cats with and without T. foetus infection and in experimentally infected kittens. Naturally infected cats showed increased prevalence and abundance of Megamonas and Helicobacter genera, while experimentally infected kittens had lower abundance of Dialister and Megamonas and higher abundance of Betaproteobacteria class and Succinivibrionaceae family post-infection.
Article
Veterinary Sciences
Jody L. L. Gookin, Sandra J. J. Strong, Jose M. Bruno-Barcena, Stephen H. H. Stauffer, Shelby Williams, Erica Wassack, M. Andrea Azcarate-Peril, Marko Estrada, Alexis Seguin, Joerg Balzer, Gigi Davidson
Summary: This study investigates the effects of administering kitten-origin Enterococcus hirae probiotics to weaned shelter kittens. The results show that the probiotic significantly reduces the incidence of diarrhea in the kittens, indicating its potential as a preventative health measure.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Jody L. Gookin, Ashley N. Hartley, Kathleen M. Aicher, Kyle G. Mathews, Rachel Cullen, John M. Cullen, Benjamin J. Callahan, Devorah M. Stowe, Gabriela S. Seiler, Megan E. Jacob, Jason W. Arnold, M. Andrea Azcarate-Peril, Stephen H. Stauffer
Summary: Until now, there has been no investigation on the culture-independent microbiome of bile from dogs. However, it is routine to collect bile under ultrasound guidance. It remains unknown whether healthy dogs have uncultivable bacteria or a core microbiota in their bile, which is crucial for understanding biliary infection and exploring other biliary diseases.
Article
Pathology
Megan E. Schreeg, John M. Cullen, James Robertson, Jody L. Gookin
Summary: This study aimed to evaluate the microanatomy of the major duodenal papilla (MDP) and its association with triaditis in cats. Histologic assessment of various organs was performed in 124 client-owned cats postmortem. The results showed that cats with triaditis had a conjoined ductular network at the MDP and inflammation of the MDP (MDPitis). Additionally, neoplasia, particularly lymphoma, was common in these cats, with a specific type called enteropathy-associated T-cell lymphoma type 2 (EATL2) being associated with triaditis and MDPitis. These findings suggest that the anatomy and inflammation of the MDP may play a role in the development of triaditis and further research is needed to understand the relationships between triaditis, MDPitis, and EATL2.
VETERINARY PATHOLOGY
(2023)
Article
Gastroenterology & Hepatology
Sylvia H. Ferguson, Derek M. Foster, Barbara Sherry, Scott T. Magness, Dahlia M. Nielsen, Jody L. Gookin
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
(2019)