Crosstalk between Tryptophan Metabolism and Cardiovascular Disease, Mechanisms, and Therapeutic Implications

Cardiac Extracellular Vesicles in Normal and Infarcted Heart

(2016) Dimitry Chistiakov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Editorial (Thematic Issue: Mechanisms of Atherogenesis and Development of Anti-Atherosclerotic Therapy)

(2015) Alexander Orekhov   CURRENT PHARMACEUTICAL DESIGN

Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development

(2015) Jennifer E. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiovascular disease in Europe 2014: epidemiological update

(2014) Melanie Nichols et al.   EUROPEAN HEART JOURNAL

Neopterin and kynurenine–tryptophan ratio as predictors of coronary events in older adults, the Hordaland Health Study

(2013) Gerhard Sulo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Obesity-related dysregulation of the Tryptophan-Kynurenine metabolism: Role of age and parameters of the metabolic syndrome

(2013) Harald Mangge et al.   Obesity

Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase

(2012) Mee Young Chang et al.   CANCER BIOLOGY & THERAPY

The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice

(2012) Lei Zhang et al.   EUROPEAN HEART JOURNAL

Kynurenines in the CNS: recent advances and new questions

(2012) László Vécsei et al.   NATURE REVIEWS DRUG DISCOVERY

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

3-Hydroxykynurenine: An intriguing molecule exerting dual actions in the Central Nervous System

(2012) Ana Laura Colín-González et al.   NEUROTOXICOLOGY

Systemic Markers of Interferon-γ–Mediated Immune Activation and Long-Term Prognosis in Patients With Stable Coronary Artery Disease

(2010) Eva Ringdal Pedersen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Relationship between an increased serum kynurenine/tryptophan ratio and atherosclerotic parameters in hemodialysis patients

(2010) Akihiko KATO et al.   Hemodialysis International

Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion

(2010) Sun-Mi Lee et al.   IMMUNOLOGY LETTERS

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

The Role of Tryptophan Catabolism along the Kynurenine Pathway in Acute Ischemic Stroke

(2010) Raf Brouns et al.   NEUROCHEMICAL RESEARCH

Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere Vascular Study

(2009) Petri Niinisalo et al.   ANNALS OF MEDICINE

Curcumin Suppresses the Induction of Indoleamine 2,3-Dioxygenase by Blocking the Janus-activated Kinase-Protein Kinase Cδ-STAT1 Signaling Pathway in Interferon-γ-stimulated Murine Dendritic Cells

(2008) Young-Il Jeong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus

(2008) Katalin Sas et al.   NEUROBIOLOGY OF DISEASE

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?

(2008) Thomas J. Connor et al.   NEUROSCIENCE LETTERS

Indoleamine 2,3‐dioxygenase activity associates with cardiovascular risk factors: The Health 2000 study

(2008) P. Niinisalo et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION