NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury

Omega-3 fatty acids regulate NLRP3 inflammasome activation and prevent behavior deficits after traumatic brain injury

(2017) Chao Lin et al.   EXPERIMENTAL NEUROLOGY

NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury

(2017) James P. Barrett et al.   Journal of Neuroinflammation

NADPH oxidase in brain injury and neurodegenerative disorders

(2017) Merry W. Ma et al.   Molecular Neurodegeneration

NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury

(2016) Alok Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation in animal models of traumatic brain injury

(2016) Chong-Chi Chiu et al.   JOURNAL OF NEUROSCIENCE METHODS

ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury

(2016) Letteria Minutoli et al.   Oxidative Medicine and Cellular Longevity

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

The pathogenic role of the inflammasome in neurodegenerative diseases

(2015) Leslie C. Freeman et al.   JOURNAL OF NEUROCHEMISTRY

Exosome-mediated inflammasome signaling after central nervous system injury

(2015) Juan Pablo de Rivero Vaccari et al.   JOURNAL OF NEUROCHEMISTRY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Traumatic Brain Injury and NADPH Oxidase: A Deep Relationship

(2015) Cristina Angeloni et al.   Oxidative Medicine and Cellular Longevity

Proline-, glutamic acid-, and leucine-rich protein 1 mediates estrogen rapid signaling and neuroprotection in the brain

(2015) Gangadhara R. Sareddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amelioration of nicotinamide adenine dinucleotide phosphate–oxidase mediated stress reduces cell death after blast-induced traumatic brain injury

(2015) Brandon P. Lucke-Wold et al.   Translational Research

Military-related traumatic brain injury and neurodegeneration

(2014) Ann C. McKee et al.   Alzheimers & Dementia

Oxidative Stress in Traumatic Brain Injury

(2014) Ana Rodriguez-Rodriguez et al.   CURRENT MEDICINAL CHEMISTRY

Activation and Regulation of Cellular Inflammasomes: Gaps in Our Knowledge for Central Nervous System Injury

(2014) Juan Pablo de Rivero Vaccari et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pyroptotic Neuronal Cell Death Mediated by the AIM2 Inflammasome

(2014) Stephanie E Adamczak et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammasomes in the CNS

(2014) John G. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

NADPH oxidase inhibition improves neurological outcome in experimental traumatic brain injury

(2014) Xin-Yu Lu et al.   NEUROCHEMISTRY INTERNATIONAL

Expression and clinical significance of non-phagocytic cell oxidase 2 and 4 after human traumatic brain injury

(2014) Zhen Li et al.   NEUROLOGICAL SCIENCES

Inflammasomes in neuroinflammation and changes in brain function: a focused review

(2014) Gaurav Singhal et al.   Frontiers in Neuroscience

The Quest for Selective Nox Inhibitors and Therapeutics: Challenges, Triumphs and Pitfalls

(2013) Eugenia Cifuentes-Pagano et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury

(2013) Sean J Cooney et al.   Journal of Neuroinflammation

Progressive Neurodegeneration After Experimental Brain Trauma

(2013) David J. Loane et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Expression of the NLRP3 Inflammasome in Cerebral Cortex After Traumatic Brain Injury in a Rat Model

(2013) Huan-Dong Liu et al.   NEUROCHEMICAL RESEARCH

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

(2012) Alok Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

(2012) Sebastian Altenhöfer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Apocynin reduces reactive oxygen species concentrations in exhaled breath condensate in asthmatics

(2012) J. Stefanska et al.   EXPERIMENTAL LUNG RESEARCH

Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome

(2012) Stephanie Adamczak et al.   JOURNAL OF NEUROSURGERY

Hydrogen peroxide and nitrite reduction in exhaled breath condensate of COPD patients

(2012) J. Stefanska et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Understanding Secondary Injury

(2012) Richard Ben Borgens et al.   QUARTERLY REVIEW OF BIOLOGY

NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

(2011) Gregory J. Gatto et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Mild Traumatic Brain Injury Results in Extensive Neuronal Degeneration in the Cerebral Cortex

(2011) Xiang Gao et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury

(2011) Adam Chodobski et al.   Translational Stroke Research

Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin-4?

(2010) Melissa D. Laird et al.   JOURNAL OF NEUROCHEMISTRY

Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury

(2010) Kenji Dohi et al.   Journal of Neuroinflammation

Inflammasome signaling at the heart of central nervous system pathology

(2010) Swarupa Chakraborty et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Delayed reduction in hippocampal postsynaptic density protein-95 expression temporally correlates with cognitive dysfunction following controlled cortical impact in mice

(2010) Chandramohan Wakade et al.   JOURNAL OF NEUROSURGERY

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice

(2009) KA Jackman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

Role of Dickkopf-1, an Antagonist of the Wnt/ -Catenin Signaling Pathway, in Estrogen-Induced Neuroprotection and Attenuation of Tau Phosphorylation

(2008) Q.-G. Zhang et al.   JOURNAL OF NEUROSCIENCE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog

(2007) L.H. Mbye et al.   EXPERIMENTAL NEUROLOGY

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION