Fluorous-tag assisted synthesis of bile acid–bisphosphonate conjugates via orthogonal click reactions: an access to potential anti-resorption bone drugs

Oral delivery of zoledronic acid by non-covalent conjugation with lysine-deoxycholic acid: In vitro characterization and in vivo anti-osteoporotic efficacy in ovariectomized rats

(2016) Ok-Cheol Jeon et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

One-pot fabrication of robust interpenetrating hydrogels via orthogonal click reactions

(2016) Takuya Murakami et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Fluorous-Tag Assisted Syntheses of Sulfated Keratan Sulfate Oligosaccharide Fragments

(2016) Sayantan Bhaduri et al.   ORGANIC LETTERS

Assembly of a Complex Branched Oligosaccharide by Combining Fluorous-Supported Synthesis and Stereoselective Glycosylations using Anomeric Sulfonium Ions

(2015) Wei Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Automated Solution-Phase Synthesis of Insect Glycans to Probe the Binding Affinity of Pea Enation Mosaic Virus

(2015) Shu-Lun Tang et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-catalysed azide–alkyne cycloadditions (CuAAC): an update

(2015) Estela Haldón et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly efficient one-pot multienzyme (OPME) synthesis of glycans with fluorous-tag assisted purification

(2014) Joel Hwang et al.   CHEMICAL COMMUNICATIONS

Thiyl Radicals in Organic Synthesis

(2014) Fabrice Dénès et al.   CHEMICAL REVIEWS

Bisphosphonates: therapeutics potential and recent advances in drug delivery

(2014) Mohammad Fazil et al.   DRUG DELIVERY

Recent progress on fluorous synthesis of biologically interesting compounds

(2014) Zhong-Xing Jiang et al.   MOLECULAR DIVERSITY

Thiol-yne ‘click’/coupling chemistry and recent applications in polymer and materials synthesis and modification

(2014) Andrew B. Lowe   POLYMER

Functional Iron Oxide Magnetic Nanoparticles with Hyperthermia-Induced Drug Release Ability by Using a Combination of Orthogonal Click Reactions

(2013) Thuy T. T. N'Guyen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry

(2013) Devatha P. Nair et al.   CHEMISTRY OF MATERIALS

Synthesis and in vitro cytotoxicity of deoxyadenosine–bile acid conjugates linked with 1,2,3-triazole

(2013) Daniela Perrone et al.   NEW JOURNAL OF CHEMISTRY

Triazole-based inhibitors of geranylgeranyltransferase II

(2012) Xiang Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Preparation of Bifunctional Mesoporous Silica Nanoparticles by Orthogonal Click Reactions and Their Application in Cooperative Catalysis

(2012) Arne T. Dickschat et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis, characterization and biological activity of hydroxyl-bisphosphonic analogs of bile acids

(2012) Olga Bortolini et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Monoconjugated and Multiply Conjugated Oligonucleotides by “Click Thiol” Thiol-Michael-Type Additions and by Combination with CuAAC “Click Huisgen”

(2012) Albert Meyer et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

(2012) Anke J Roelofs et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Development of Novel Bisphosphonate Prodrugs of Doxorubicin for Targeting Bone Metastases That Are Cleaved pH Dependently or by Cathepsin B: Synthesis, Cleavage Properties, and Binding Properties to Hydroxyapatite As Well As Bone Matrix

(2012) Katrin Hochdörffer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enhanced Oral Absorption of Ibandronate via Complex Formation with Bile Acid Derivative

(2012) Jin Woo Park et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications

(2012) Alessandro Massi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Polyurethane (PU)-derived photoactive and copper-free clickable surface based on perfluorophenyl azide (PFPA) chemistry

(2012) Lingdong Li et al.   Journal of Materials Chemistry B

Synthesis of Dendritic Polyglycerol Anions and Their Efficiency Toward L-Selectin Inhibition

(2011) Marie Weinhart et al.   BIOMACROMOLECULES

Bisphosphonates: The first 40years

(2011) R. Graham G. Russell   BONE

A Facile Cu(I)/TF-BiphamPhos-Catalyzed Asymmetric Approach to Unnatural α-Amino Acid Derivatives Containinggem-Bisphosphonates

(2011) Zhi-Yong Xue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiol-Yne Chemistry: A Powerful Tool for Creating Highly Functional Materials

(2010) Richard Hoogenboom   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical and molecular mechanisms of action of bisphosphonates

(2010) Michael J. Rogers et al.   BONE

Delivery of zoledronic acid encapsulated in folate-targeted liposome results in potent in vitro cytotoxic activity on tumor cells

(2010) Hilary Shmeeda et al.   JOURNAL OF CONTROLLED RELEASE

An Insight into the Radical Thiol/Yne Coupling: The Emergence of Arylalkyne-Tagged Sugars for the Direct Photoinduced Glycosylation of Cysteine-Containing Peptides

(2010) Matteo Minozzi et al.   JOURNAL OF ORGANIC CHEMISTRY

Thiol−Ene Induced Diphosphonic Acid Functionalization of Superparamagnetic Iron Oxide Nanoparticles

(2010) Ryan D. Rutledge et al.   LANGMUIR

Synthesis and Applications of Biomedical and Pharmaceutical Polymers via Click Chemistry Methodologies

(2009) Maarten van Dijk et al.   BIOCONJUGATE CHEMISTRY

Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials

(2009) Rhiannon K. Iha et al.   CHEMICAL REVIEWS

Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo

(2009) Anke J Roelofs et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bisphosphonates: Mechanism of Action and Role in Clinical Practice

(2009) Matthew T. Drake et al.   MAYO CLINIC PROCEEDINGS

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

(2009) Andrew B. Lowe   Polymer Chemistry

Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ-T Lymphocytes-Mediated Activation Mechanism

(2008) Daniele Simoni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase

(2008) James E. Dunford et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbon Dioxide Solubility Enhancement through Silicone Functionalization: “CO2-philic” Oligo(dimethylsiloxane)-substituted Diphosphonates∗

(2008) Julie A. Dzielawa et al.   SEPARATION SCIENCE AND TECHNOLOGY