Bisphosphonates: therapeutics potential and recent advances in drug delivery

Raloxifene and alendronate containing thin mesoporous titanium oxide films improve implant fixation to bone

(2013) N. Harmankaya et al.   Acta Biomaterialia

Cast adhesive polyelectrolyte complex particle films of unmodified or maltose-modified poly(ethyleneimine) and cellulose sulphate: fabrication, film stability and retarded release of zoledronate

(2013) Bernhard Torger et al.   Biointerphases

The bisphosphonates: risks and benefits of long term use

(2013) Anne Pernille Hermann et al.   CURRENT OPINION IN PHARMACOLOGY

Suitability of liposomal carriers for systemic delivery of risedronate using the pulmonary route

(2013) Maha Nasr et al.   DRUG DELIVERY

Enteric-coated alendronate sodium nanoliposomes: a novel formula to overcome barriers for the treatment of osteoporosis

(2013) Khaled Mohamed Hosny et al.   Expert Opinion on Drug Delivery

Improvement in Bone Properties by Using Risedronate Adsorbed Hydroxyapatite Novel Nanoparticle Based Formulation in a Rat Model of Osteoporosis

(2013) H. Sahana et al.   Journal of Biomedical Nanotechnology

Liposome encapsulation of zoledronic acid results in major changes in tissue distribution and increase in toxicity

(2013) Hilary Shmeeda et al.   JOURNAL OF CONTROLLED RELEASE

Biomedical applications of bisphosphonates

(2013) Elisabeth V. Giger et al.   JOURNAL OF CONTROLLED RELEASE

Micro-structured hydroxyapatite microspheres for local delivery of alendronate and BMP-2 carriers

(2013) Jin Hyung Lee et al.   MATERIALS LETTERS

Alendronate coated poly-lactic-co-glycolic acid (PLGA) nanoparticles for active targeting of metastatic breast cancer

(2012) Sanjay I. Thamake et al.   BIOMATERIALS

Improved oral bioavailability of alendronate via the mucoadhesive liposomal delivery system

(2012) Hyo-Kyung Han et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Silicon-stabilized α-tricalcium phosphate and its use in a calcium phosphate cement: Characterization and cell response

(2011) Gemma Mestres et al.   Acta Biomaterialia

The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis

(2011) Hen-Yu Liu et al.   BIOMATERIALS

Topically administered Risedronate shows powerful anti-osteoporosis effect in ovariectomized mouse model

(2011) So Hee Nam et al.   BONE

Ion pairs of risedronate for transdermal delivery and enhanced permeation rate on hairless mouse skin

(2011) So Hee Nam et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Bone targeting for the treatment of osteoporosis

(2011) Tessa Luhmann et al.   JOURNAL OF CONTROLLED RELEASE

Bone metastasis targeting: A novel approach to reach bone using Zoledronate anchored PLGA nanoparticle as carrier system loaded with Docetaxel

(2011) Kiran Ramanlal Chaudhari et al.   JOURNAL OF CONTROLLED RELEASE

Nanotechnologies to use bisphosphonates as potent anticancer agents: the effects of zoledronic acid encapsulated into liposomes

(2011) Monica Marra et al.   Nanomedicine-Nanotechnology Biology and Medicine

Investigation of alendronate-doped apatitic cements as a potential technology for the prevention of osteoporotic hip fractures: Critical influence of the drug introduction mode on the in vitro cement properties

(2010) Verena Schnitzler et al.   Acta Biomaterialia

In vivo bone augmentation in an osteoporotic environment using bisphosphonate-loaded calcium deficient apatite

(2010) Elise Verron et al.   BIOMATERIALS

Combined effects of zoledronate and mechanical stimulation on bone adaptation in an axially loaded mouse tibia

(2010) V.A. Stadelmann et al.   CLINICAL BIOMECHANICS

Epidemiology of hip fracture: Worldwide geographic variation

(2010) DineshK Dhanwal et al.   Indian Journal of Orthopaedics

Self-assembly nanoparticles for the delivery of bisphosphonates into tumors

(2010) G. Salzano et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a novel transdermal patch of alendronate, a nitrogen-containing bisphosphonate, for the treatment of osteoporosis

(2010) Kosuke Kusamori et al.   JOURNAL OF BONE AND MINERAL RESEARCH

In situ fabrication of alendronate-loaded calcium phosphate microspheres: Controlled release for inhibition of osteoclastogenesis

(2010) Chan Woo Kim et al.   JOURNAL OF CONTROLLED RELEASE

Synthesis of calcium phosphate-binding liposome for drug delivery

(2009) Takahisa Anada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nanoparticle-based targeted drug delivery

(2009) Rajesh Singh et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Locally Delivered Bisphosphonate for Enhancement of Bone Formation and Implant Fixation

(2009) J Dennis Bobyn et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

A novel PHBV/HA microsphere releasing system loaded with alendronate

(2009) Wei Huang et al.   Materials Science & Engineering C-Materials for Biological Applications

Bisphosphonates: Mechanism of Action and Role in Clinical Practice

(2009) Matthew T. Drake et al.   MAYO CLINIC PROCEEDINGS

A novel biomaterial for osteotropic drug nanocarriers: synthesis and biocompatibility evaluation of a PLGA–ALE conjugate

(2009) Rosario Pignatello et al.   Nanomedicine

Preparation of Alendronate Liposomes for Enhanced Stability and Bioactivity: In Vitro and In Vivo Characterization

(2008) Hila Epstein et al.   AAPS Journal

Biocompatibility of poly(d,l-lactide-co-glycolide) nanoparticles conjugated with alendronate

(2008) Elisabetta Cenni et al.   BIOMATERIALS

Effect of combined local treatment with zoledronic acid and basic fibroblast growth factor on implant fixation in ovariectomized rats

(2008) Ying Gao et al.   BONE

Alendronate and Pamidronate calcium phosphate bone cements: Setting properties and in vitro response of osteoblast and osteoclast cells

(2008) S PANZAVOLTA et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Enhancing Alendronate Release from a Novel PLGA/Hydroxyapatite Microspheric System for Bone Repairing Applications

(2008) Xuetao Shi et al.   PHARMACEUTICAL RESEARCH