Development of Novel Bisphosphonate Prodrugs of Doxorubicin for Targeting Bone Metastases That Are Cleaved pH Dependently or by Cathepsin B: Synthesis, Cleavage Properties, and Binding Properties to Hydroxyapatite As Well As Bone Matrix

Title
Development of Novel Bisphosphonate Prodrugs of Doxorubicin for Targeting Bone Metastases That Are Cleaved pH Dependently or by Cathepsin B: Synthesis, Cleavage Properties, and Binding Properties to Hydroxyapatite As Well As Bone Matrix
Authors
Keywords
-
Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 55, Issue 17, Pages 7502-7515
Publisher
American Chemical Society (ACS)
Online
2012-08-13
DOI
10.1021/jm300493m

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