CAMK2γ in intestinal epithelial cells modulates colitis-associated colorectal carcinogenesis via enhancing STAT3 activation

Strategies and Approaches of Targeting STAT3 for Cancer Treatment

(2016) Steffanie L. Furtek et al.   ACS Chemical Biology

Deletion of Interleukin-6 Attenuates Pressure Overload-Induced Left Ventricular Hypertrophy and DysfunctionNovelty and Significance

(2016) Lin Zhao et al.   CIRCULATION RESEARCH

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease−Associated Colorectal Cancers

(2016) Ana I. Robles et al.   GASTROENTEROLOGY

Inflammatory networks underlying colorectal cancer

(2016) Audrey Lasry et al.   NATURE IMMUNOLOGY

Colitis-associated colon cancer: Is it in your genes?

(2015) Lauren Van Der Kraak   WORLD JOURNAL OF GASTROENTEROLOGY

The emerging role of CaMKII in cancer

(2015) Yan-yang Wang et al.   Oncotarget

The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-γ in colitis

(2015) Akira Sato et al.   Scientific Reports

Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival

(2014) Jalaj Gupta et al.   CANCER CELL

Pro-Oncogenic Role of Alternative p38 Mitogen-Activated Protein Kinases p38  and p38 , Linking Inflammation and Cancer in Colitis-Associated Colon Cancer

(2014) P. del Reino et al.   CANCER RESEARCH

Colitis-associated neoplasia: molecular basis and clinical translation

(2014) Sebastian Foersch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

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(2014) Masakazu Yashiro   WORLD JOURNAL OF GASTROENTEROLOGY

Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically

(2013) Tracy L. Putoczki et al.   CANCER CELL

Tumor fibroblast–derived epiregulin promotes growth of colitis-associated neoplasms through ERK

(2013) Clemens Neufert et al.   JOURNAL OF CLINICAL INVESTIGATION

Berbamine Inhibits the Growth of Liver Cancer Cells and Cancer-Initiating Cells by Targeting Ca2+/Calmodulin-Dependent Protein Kinase II

(2013) Z. Meng et al.   MOLECULAR CANCER THERAPEUTICS

Tracing the cellular origin of cancer

(2013) Cédric Blanpain   NATURE CELL BIOLOGY

Cancer and Inflammation: An Old Intuition with Rapidly Evolving New Concepts

(2012) Giorgio Trinchieri   Annual Review of Immunology

CaMKII  , a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine

(2012) Y. Gu et al.   BLOOD

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

(2012) Jie Liang et al.   CANCER CELL

SFRP5 inhibits gastric epithelial cell migration induced by macrophage-derived Wnt5a

(2012) Chenghai Zhao et al.   CARCINOGENESIS

Risk of Colorectal Cancer in Patients With Ulcerative Colitis: A Meta-analysis of Population-Based Cohort Studies

(2012) Tine Jess et al.   Clinical Gastroenterology and Hepatology

Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations

(2012) Núria Planell et al.   GUT

Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks

(2012) Martina Perše et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer

(2012) Deborah C. Rubin et al.   Frontiers in Immunology

Wnt/Ca2+ signaling pathway: a brief overview

(2011) Antara De   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Intestinal Inflammation and Cancer

(2011) Thomas A. Ullman et al.   GASTROENTEROLOGY

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

(2011) Wendy Huang et al.   NATURE

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(2010) Sergei I. Grivennikov et al.   CELL

Expression profiling of Wnt family of genes in normal and inflammatory bowel disease primary human intestinal myofibroblasts and normal human colonic crypt epithelial cells

(2010) K. R. Hughes et al.   INFLAMMATORY BOWEL DISEASES

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

(2010) K. Brandl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased pulmonary Wnt (wingless/integrated)-signaling in patients with sarcoidosis

(2010) Bettina Levänen et al.   RESPIRATORY MEDICINE

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional Integration of TLR2 and TLR4 Signaling at the NCoR Derepression Checkpoint

(2009) Wendy Huang et al.   MOLECULAR CELL

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

The   isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption

(2009) J. Backs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages

(2008) X. Liu et al.   BLOOD

Activated Ca2+/Calmodulin-Dependent Protein Kinase II  Is a Critical Regulator of Myeloid Leukemia Cell Proliferation

(2008) J. Si et al.   CANCER RESEARCH

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies

(2008) Peter Laszlo Lakatos et al.   WORLD JOURNAL OF GASTROENTEROLOGY