Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression

Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers

(2016) Campbell D. Lawson et al.   CANCER RESEARCH

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer

(2016) Tania M. Puvirajesinghe et al.   Nature Communications

Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I

(2016) Randall A. Dass et al.   PLoS Genetics

Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells

(2015) N. Borcherding et al.   CANCER RESEARCH

Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium

(2015) Kevin Roarty et al.   JOURNAL OF CELL BIOLOGY

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

(2015) Bartlomiej Waclaw et al.   NATURE

Intratumoral Heterogeneity in a Trp53-Null Mouse Model of Human Breast Cancer

(2015) M. Zhang et al.   Cancer Discovery

Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer

(2014) Jian Shi et al.   CANCER CELL

A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis

(2014) Taranjit S. Gujral et al.   CELL

Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling

(2014) C. Henry et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

ERM proteins in cancer progression

(2014) J. Clucas et al.   JOURNAL OF CELL SCIENCE

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

(2014) Allison S. Cleary et al.   NATURE

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

(2014) Rumela Chakrabarti et al.   NATURE CELL BIOLOGY

Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

(2014) J Dembowy et al.   ONCOGENE

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes

(2013) Aleix Prat et al.   BREAST CANCER RESEARCH AND TREATMENT

WNT5A Inhibits Metastasis and Alters Splicing of Cd44 in Breast Cancer Cells

(2013) Wen Jiang et al.   PLoS One

Paracrine Wnt signaling both promotes and inhibits human breast tumor growth

(2013) J. L. Green et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

(2013) Adam D Pfefferle et al.   GENOME BIOLOGY

Breast cancer intratumor genetic heterogeneity: causes and implications

(2012) Charlotte KY Ng et al.   Expert Review of Anticancer Therapy

Integrated Analyses of microRNAs Demonstrate Their Widespread Influence on Gene Expression in High-Grade Serous Ovarian Carcinoma

(2012) Chad J. Creighton et al.   PLoS One

ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth

(2012) Suping Zhang et al.   PLoS One

Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis

(2012) H.-Y. H. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt Signaling in Mammalian Development: Lessons from Mouse Genetics

(2012) J. Wang et al.   Cold Spring Harbor Perspectives in Biology

Alternative Wnt Pathways and Receptors

(2012) R. van Amerongen   Cold Spring Harbor Perspectives in Biology

Wnt Signaling in Cancer

(2012) P. Polakis   Cold Spring Harbor Perspectives in Biology

β-Catenin Dosage Is a Critical Determinant of Tracheal Basal Cell Fate Determination

(2011) Heather M. Brechbuhl et al.   AMERICAN JOURNAL OF PATHOLOGY

TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumab

(2011) Stefan Glück et al.   BREAST CANCER RESEARCH AND TREATMENT

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion

(2011) Tiago C. Luis et al.   Cell Stem Cell

Ezrin, Radixin and Moesin: key regulators of membrane–cortex interactions and signaling

(2011) Amanda L Neisch et al.   CURRENT OPINION IN CELL BIOLOGY

A context-dependent combination of Wnt receptors controls axis elongation and leg development in a short germ insect

(2011) A. Beermann et al.   DEVELOPMENT

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Insight into the heterogeneity of breast cancer through next-generation sequencing

(2011) Hege G. Russnes et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells

(2011) J. I. Herschkowitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role for ERM proteins in cell adhesion and migration

(2011) Monique Arpin et al.   Cell Adhesion & Migration

Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome

(2010) Andrey I. Khramtsov et al.   AMERICAN JOURNAL OF PATHOLOGY

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors

(2010) L. Grumolato et al.   GENES & DEVELOPMENT

β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

(2010) Felipe C Geyer et al.   MODERN PATHOLOGY

Deconstructing the molecular portraits of breast cancer

(2010) Aleix Prat et al.   Molecular Oncology

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

Selective targeting of radiation-resistant tumor-initiating cells

(2010) Mei Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Mammary development meets cancer genomics

(2009) Aleix Prat et al.   NATURE MEDICINE

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

An olive branch to two theories

(2009) Leonie Welberg   NATURE REVIEWS NEUROSCIENCE

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis

(2008) Chad J. Creighton et al.   JOURNAL OF CLINICAL ONCOLOGY

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis

(2008) Kristoffer Weber et al.   MOLECULAR THERAPY

The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC

(2008) L Ren et al.   ONCOGENE

A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions

(2008) C. J. Creighton et al.   RNA