Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium

Identification of multipotent mammary stem cells by protein C receptor expression

(2014) Daisong Wang et al.   NATURE

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

(2014) Allison S. Cleary et al.   NATURE

In situ identification of bipotent stem cells in the mammary gland

(2014) Anne C. Rios et al.   NATURE

The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance

(2014) Yongliang Huo et al.   NATURE CELL BIOLOGY

A Role for Matrix Metalloproteinases in Regulating Mammary Stem Cell Function via the Wnt Signaling Pathway

(2013) Kai Kessenbrock et al.   Cell Stem Cell

PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively

(2013) Wenting Zhu et al.   DEVELOPMENTAL BIOLOGY

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

(2013) Maria Carolina Florian et al.   NATURE

A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro

(2013) S. J. Habib et al.   SCIENCE

The Role of Ryk and Ror Receptor Tyrosine Kinases in Wnt Signal Transduction

(2013) J. Green et al.   Cold Spring Harbor Perspectives in Biology

Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland

(2012) Renée van Amerongen et al.   Cell Stem Cell

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development

(2012) Renée van Amerongen et al.   DEVELOPMENTAL BIOLOGY

Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis

(2012) H.-Y. H. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Wnt Pathways and Receptors

(2012) R. van Amerongen   Cold Spring Harbor Perspectives in Biology

Pregnancy-Induced Noncoding RNA (PINC) Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation

(2012) Amy N. Shore et al.   PLoS Genetics

Mammary gland development

(2012) Hector Macias et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein

(2011) M. Harterink et al.   DEVELOPMENT

Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture

(2011) Amira L. Pavlovich et al.   EXPERIMENTAL CELL RESEARCH

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways

(2011) Giovanna Nalesso et al.   JOURNAL OF CELL BIOLOGY

Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14

(2011) M.-L. Asselin-Labat et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

Integrated morphodynamic signalling of the mammary gland

(2011) Nikolce Gjorevski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteomic profiling of secretome and adherent plasma membranes from distinct mammary epithelial cell subpopulations

(2011) Hong Ji et al.   PROTEOMICS

Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome

(2010) Andrey I. Khramtsov et al.   AMERICAN JOURNAL OF PATHOLOGY

Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

(2010) Yi Arial Zeng et al.   Cell Stem Cell

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors

(2010) L. Grumolato et al.   GENES & DEVELOPMENT

s-SHIP promoter expression marks activated stem cells in developing mouse mammary tissue

(2010) L. Bai et al.   GENES & DEVELOPMENT

Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization

(2010) M. Nishita et al.   MOLECULAR AND CELLULAR BIOLOGY

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

(2010) John T. Connelly et al.   NATURE CELL BIOLOGY

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

Mammary Epithelial Reconstitution with Gene-Modified Stem Cells Assigns Roles to Stat5 in Luminal Alveolar Cell Fate Decisions, Differentiation, Involution and Mammary Tumor Formation

(2010) Vida Vafaizadeh et al.   STEM CELLS

A Novel Lung Metastasis Signature Links Wnt Signaling with Cancer Cell Self-Renewal and Epithelial-Mesenchymal Transition in Basal-like Breast Cancer

(2009) Theresa A. DiMeo et al.   CANCER RESEARCH

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis

(2009) L. M. McCaffrey et al.   GENES & DEVELOPMENT

Ror2 Receptor Requires Tyrosine Kinase Activity to Mediate Wnt5A Signaling

(2009) Amanda Mikels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proximal events in Wnt signal transduction

(2009) Stephane Angers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage

(2009) Nisha M. Badders et al.   PLoS One

Global expression profiling reveals regulation of CTGF/CCN2 during lactogenic differentiation

(2009) Weihan Wang et al.   Journal of Cell Communication and Signaling

Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

(2008) Howard Kendrick et al.   BMC GENOMICS

Opposing Wnt Pathways Orient Cell Polarity during Organogenesis

(2008) Jennifer L. Green et al.   CELL

Lentiviral Transduction of Mammary Stem Cells for Analysis of Gene Function during Development and Cancer

(2008) Bryan E. Welm et al.   Cell Stem Cell

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation

(2008) S.-W. Cha et al.   DEVELOPMENT

Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

(2008) Andrew J. Ewald et al.   DEVELOPMENTAL CELL

Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis

(2008) Chad J. Creighton et al.   JOURNAL OF CLINICAL ONCOLOGY

A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis

(2008) Kristoffer Weber et al.   MOLECULAR THERAPY

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling