Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma

A simple, low-cost staining method for rapid-throughput analysis of tumor spheroids

(2016) Frank Eckerdt et al.   BIOTECHNIQUES

SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer

(2016) Osmel Companioni Nápoles et al.   JOURNAL OF GASTROENTEROLOGY

Reversion of malignant phenotypes of human glioblastoma cells by β-elemene through β-catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules

(2015) Tingzhun Zhu et al.   Journal of Translational Medicine

Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells

(2015) Antonella Sassano et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamic control of type I IFN signalling by an integrated network of negative regulators

(2015) Rebecca A. Porritt et al.   TRENDS IN IMMUNOLOGY

EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway

(2015) Zhuo Wang et al.   Oncotarget

EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis

(2014) Haizhong Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

Interferon Receptor Signaling in Malignancy: A Network of Cellular Pathways Defining Biological Outcomes

(2014) E. N. Fish et al.   MOLECULAR CANCER RESEARCH

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Hypoxia inducible factor 1α-mediated LOX expression correlates with migration and invasion in epithelial ovarian cancer

(2013) FANG JI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Interferons and Their Antitumor Properties

(2013) Leonidas C. Platanias   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Schlafen Family of Proteins and Their Regulation by Interferons

(2013) Evangelos Mavrommatis et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition

(2013) Maya Srikanth et al.   NEURO-ONCOLOGY

Isoform level expression profiles provide better cancer signatures than gene level expression profiles

(2013) ZhongFa Zhang et al.   Genome Medicine

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11

(2012) Manqing Li et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells

(2012) C-H Yoon et al.   ONCOGENE

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

(2012) G. Zoppoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter

(2010) Kazuya Motomura et al.   CANCER

Role of Interferon α (IFNα)-inducible Schlafen-5 in Regulation of Anchorage-independent Growth and Invasion of Malignant Melanoma Cells

(2010) Efstratios Katsoulidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence

(2009) Olivia Bustos et al.   GENE

Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research

(2009) S. Madhavan et al.   MOLECULAR CANCER RESEARCH

Subcellular localization of the Schlafen protein family

(2008) Brent Neumann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE