Isoform level expression profiles provide better cancer signatures than gene level expression profiles

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data

(2010) Ravi Gupta et al.   BMC BIOINFORMATICS

Biomarker-Driven Early Clinical Trials in Oncology

(2010) Daniel S. W. Tan et al.   CANCER JOURNAL

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

(2010) C. J. David et al.   GENES & DEVELOPMENT

Isoform-specific p73 knockout mice reveal a novel role for  Np73 in the DNA damage response pathway

(2010) M. T. Wilhelm et al.   GENES & DEVELOPMENT

Integrative analysis of the melanoma transcriptome

(2010) M. F. Berger et al.   GENOME RESEARCH

Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children’s Oncology Group

(2010) Ian F. Pollack et al.   JOURNAL OF NEURO-ONCOLOGY

LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer

(2010) Lydia Kriegl et al.   Journal of Translational Medicine

Ten years of genetics and genomics: what have we achieved and where are we heading?

(2010) Edith Heard et al.   NATURE REVIEWS GENETICS

Genomic Medicine — An Updated Primer

(2010) W. Gregory Feero et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans

(2010) R. McDaniell et al.   SCIENCE

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Molecular classification of solid tumours: towards pathway-driven therapeutics

(2009) C Swanton et al.   BRITISH JOURNAL OF CANCER

Structure and organization of drug-target networks: insights from genomic approaches for drug discovery

(2009) Sarath Chandra Janga et al.   Molecular BioSystems

Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

(2009) Bin Zheng et al.   MOLECULAR CELL

Alternative splicing and biological heterogeneity in prostate cancer

(2009) Prabhakar Rajan et al.   Nature Reviews Urology

Activation of Wnt/β-catenin/Tcf signaling pathway in human astrocytomas

(2009) Gangadhara Reddy Sareddy et al.   NEUROCHEMISTRY INTERNATIONAL

MMBGX: a method for estimating expression at the isoform level and detecting differential splicing using whole-transcript Affymetrix arrays

(2009) Ernest Turro et al.   NUCLEIC ACIDS RESEARCH

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exon Array Analysis of Head and Neck Cancers Identifies a Hypoxia Related Splice Variant of LAMA3 Associated with a Poor Prognosis

(2009) Carla S. Moller-Levet et al.   PLoS Computational Biology

Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling array

(2008) Gregory AC Singer et al.   BMC GENOMICS

Alternative Splicing and Tumor Progression

(2008) Claudia Ghigna et al.   CURRENT GENOMICS

Stathmin 1: a novel therapeutic target for anticancer activity

(2008) Shushan Rana et al.   Expert Review of Anticancer Therapy

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Genome-wide analysis of transcript isoform variation in humans

(2008) Tony Kwan et al.   NATURE GENETICS