Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder

α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B

(2017) Diana G Ferreira et al.   NATURE NEUROSCIENCE

Genetic insights into the neurodevelopmental origins of schizophrenia

(2017) Rebecca Birnbaum et al.   NATURE REVIEWS NEUROSCIENCE

Global inhibition of transcription causes an increase in histone H2A.Z incorporation within gene bodies

(2017) Anahita Lashgari et al.   NUCLEIC ACIDS RESEARCH

N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena

(2017) Yuanyuan Wang et al.   NUCLEIC ACIDS RESEARCH

UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex

(2017) Fen Ji et al.   STEM CELLS

The Histone Variant H2A.Z Is a Master Regulator of the Epithelial-Mesenchymal Transition

(2017) Renae Domaschenz et al.   Cell Reports

Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

(2016) Lauren L. Orefice et al.   CELL

Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval

(2016) Chun Xu et al.   CELL

Evidence from cyclostomes for complex regionalization of the ancestral vertebrate brain

(2016) Fumiaki Sugahara et al.   NATURE

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

(2016) Omer Durak et al.   NATURE NEUROSCIENCE

Epigenetic mechanisms in neurogenesis

(2016) Bing Yao et al.   NATURE REVIEWS NEUROSCIENCE

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons

(2016) Magnus Sandberg et al.   NEURON

Proliferation and Differentiation Deficits are a Major Convergence Point for Neurodevelopmental Disorders

(2016) Carl Ernst   TRENDS IN NEUROSCIENCES

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

(2015) Sophia X. Pfister et al.   CANCER CELL

Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding

(2015) Marcelo O. Dietrich et al.   CELL

Eukaryotic initiation factor 6 modulates myofibroblast differentiation at transforming growth factor- 1 transcription level via H2A.Z occupancy and Sp1 recruitment

(2015) S.-s. Yang et al.   JOURNAL OF CELL SCIENCE

Association of common variants in H2AFZ gene with schizophrenia and cognitive function in patients with schizophrenia

(2015) Ming Chang et al.   JOURNAL OF HUMAN GENETICS

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma

(2015) Chiara Vardabasso et al.   MOLECULAR CELL

Genomic Perspectives of Transcriptional Regulation in Forebrain Development

(2015) Alex S. Nord et al.   NEURON

Pluripotency Activity of Nanog Requires Biochemical Stabilization by Variant Histone Protein H2A.Z

(2015) Jiaxu Wang et al.   STEM CELLS

CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex

(2015) Tianjin Shen et al.   STEM CELLS

A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus

(2015) Sandra Lazorthes et al.   Nature Communications

Epigenetics: major regulators of embryonic neurogenesis

(2015) Tianjin Shen et al.   Science Bulletin

Unlocking epigenetic codes in neurogenesis

(2014) B. Yao et al.   GENES & DEVELOPMENT

The neurobiology and treatment of first-episode schizophrenia

(2014) R S Kahn et al.   MOLECULAR PSYCHIATRY

ANP32E is a histone chaperone that removes H2A.Z from chromatin

(2014) Arnaud Obri et al.   NATURE

ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

(2014) Hong Wen et al.   NATURE

Histone H2A.Z subunit exchange controls consolidation of recent and remote memory

(2014) Iva B. Zovkic et al.   NATURE

Every amino acid matters: essential contributions of histone variants to mammalian development and disease

(2014) Ian Maze et al.   NATURE REVIEWS GENETICS

CHD8regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

(2014) Aarathi Sugathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendrite Development Regulated by the Schizophrenia-Associated Gene FEZ1 Involves the Ubiquitin Proteasome System

(2014) Yasuhito Watanabe et al.   Cell Reports

Integrative Mechanisms of Oriented Neuronal Migration in the Developing Brain

(2013) Irina Evsyukova et al.   Annual Review of Cell and Developmental Biology

Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate

(2013) Ronny Stahl et al.   CELL

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription

(2013) Sílvia Carvalho et al.   NUCLEIC ACIDS RESEARCH

Dynamics of 5-Hydroxymethylcytosine and Chromatin Marks in Mammalian Neurogenesis

(2013) Maria A. Hahn et al.   Cell Reports

H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-Renewal and Differentiation

(2012) Gangqing Hu et al.   Cell Stem Cell

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex

(2012) Froylan Calderon de Anda et al.   NATURE NEUROSCIENCE

Proximity of H2A.Z containing nucleosome to the transcription start site influences gene expression levels in the mammalian liver and brain

(2012) Rhishikesh Bargaje et al.   NUCLEIC ACIDS RESEARCH

H2A.Z-dependent crosstalk between enhancer and promoter regulates Cyclin D1 expression

(2012) M Dalvai et al.   ONCOGENE

SIRT1 Activates MAO-A in the Brain to Mediate Anxiety and Exploratory Drive

(2011) Sergiy Libert et al.   CELL

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

Cux1 and Cux2 Regulate Dendritic Branching, Spine Morphology, and Synapses of the Upper Layer Neurons of the Cortex

(2010) Beatriz Cubelos et al.   NEURON

Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant

(2010) Ryo Matsuda et al.   NUCLEIC ACIDS RESEARCH

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

(2009) Juan E Belforte et al.   NATURE NEUROSCIENCE

H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment

(2008) Menno P. Creyghton et al.   CELL