Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

Published 2015 View Full Article

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Title
Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation
Authors
Keywords
cancer, synthetic lethality, epigenetic target, histone modification, SETD2, H3K36me3, WEE1 inhibitor, AZD1775, ATR inhibitor, CHK1 inhibitor, DNA replication, RRM2, CDK, KDM4A, H3.3K36M, iPOND, ChIP
Journal
CANCER CELL
Volume 28, Issue 5, Pages 557-568
Publisher
Elsevier BV
Online
2015-10-25
DOI
10.1016/j.ccell.2015.09.015

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