CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

(2014) Dalila Pinto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

(2014) Raphael Bernier et al.   CELL

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

REST and stress resistance in ageing and Alzheimer’s disease

(2014) Tao Lu et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

bHLH Factors in Self-Renewal, Multipotency, and Fate Choice of Neural Progenitor Cells

(2014) Itaru Imayoshi et al.   NEURON

Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate

(2013) Ronny Stahl et al.   CELL

The Chromatin Remodeler CHD7 Regulates Adult Neurogenesis via Activation of SoxC Transcription Factors

(2013) Weijun Feng et al.   Cell Stem Cell

CHD5 Is Required for Neurogenesis and Has a Dual Role in Facilitating Gene Expression and Polycomb Gene Repression

(2013) Chris M. Egan et al.   DEVELOPMENTAL CELL

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

(2013) Anke Sparmann et al.   EMBO JOURNAL

Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1

(2013) Gemma L Carvill et al.   NATURE GENETICS

Axin Directs the Amplification and Differentiation of Intermediate Progenitors in the Developing Cerebral Cortex

(2013) Wei-Qun Fang et al.   NEURON

Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

(2012) Yawei J. Yang et al.   CELL

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

(2012) Anita Rauch et al.   LANCET

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

Maintaining differentiated cellular identity

(2012) Johan Holmberg et al.   NATURE REVIEWS GENETICS

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins

(2011) A. Yoshimi et al.   BLOOD

Deletion of the RMGA and CHD2 genes in a child with epilepsy and mental deficiency

(2011) Leonardo P. Capelli et al.   European Journal of Medical Genetics

Repressor element 1 silencing transcription factor (REST) controls radial migration and temporal neuronal specification during neocortical development

(2011) G. Mandel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repressor Element 1 Silencing Transcription Factor Couples Loss of Pluripotency with Neural Induction and Neural Differentiation

(2011) Chiara Soldati et al.   STEM CELLS

Rest Promotes the Early Differentiation of Mouse ESCs but Is Not Required for Their Maintenance

(2010) Yasuhiro Yamada et al.   Cell Stem Cell

Can controversies be put to REST?

(2010) Helle F. Jørgensen et al.   NATURE

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Cdk5rap2 Interacts with Pericentrin to Maintain the Neural Progenitor Pool in the Developing Neocortex

(2010) Joshua J. Buchman et al.   NEURON

REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells

(2009) H. F. Jorgensen et al.   DEVELOPMENT

Is REST required for ESC pluripotency?

(2009) Helle F. Jørgensen et al.   NATURE

Is REST a regulator of pluripotency?

(2009) Noel J. Buckley et al.   NATURE

Disruption of chromodomain helicase DNA binding protein 2 (CHD2) causes scoliosis

(2008) Shashikant Kulkarni et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

REST maintains self-renewal and pluripotency of embryonic stem cells

(2008) Sanjay K. Singh et al.   NATURE