Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume 45, Issue 18, Pages 10861-10871
Publisher
Oxford University Press (OUP)
Online
2017-08-23
DOI
10.1093/nar/gkx742
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases
- (2016) Timothy J. Miles et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Stabilization of protein–protein interaction complexes through small molecules
- (2016) Barbara Zarzycka et al. DRUG DISCOVERY TODAY
- Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes fromMycobacterium tuberculosis
- (2016) Tim R. Blower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of a quinolone-stabilized cleavage complex of topoisomerase IV fromKlebsiella pneumoniaeand comparison with a relatedStreptococcus pneumoniaecomplex
- (2016) Dennis A. Veselkov et al. Acta Crystallographica Section D-Structural Biology
- Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases
- (2015) Kendra R. Vann et al. BIOCHEMISTRY
- New Mechanistic and Functional Insights into DNA Topoisomerases
- (2013) Stefanie Hartman Chen et al. Annual Review of Biochemistry
- Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases
- (2013) Timothy J. Miles et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and anticancer activity of dichloroplatinum(II) complexes of podophyllotoxin
- (2013) Xuan Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Therapy-related acute promyelocytic leukemia: a systematic review
- (2013) Armin Rashidi et al. MEDICAL ONCOLOGY
- On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
- (2013) Chyuan-Chuan Wu et al. NUCLEIC ACIDS RESEARCH
- Drugging Topoisomerases: Lessons and Challenges
- (2012) Yves Pommier ACS Chemical Biology
- Anthracenedione–methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles
- (2012) Chieh-Hua Lee et al. BIOCHEMICAL PHARMACOLOGY
- Probing Conformational Changes in Human DNA Topoisomerase IIα by Pulsed Alkylation Mass Spectrometry
- (2012) Yu-tsung Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage
- (2012) Timothy J. Wendorff et al. JOURNAL OF MOLECULAR BIOLOGY
- Identification of the molecular basis of doxorubicin-induced cardiotoxicity
- (2012) Sui Zhang et al. NATURE MEDICINE
- Mechanism of Generation of Therapy Related Leukemia in Response to Anti-Topoisomerase II Agents
- (2012) Ian G. Cowell et al. International Journal of Environmental Research and Public Health
- The resurgence of covalent drugs
- (2011) Juswinder Singh et al. NATURE REVIEWS DRUG DISCOVERY
- All tangled up: how cells direct, manage and exploit topoisomerase function
- (2011) Seychelle M. Vos et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
- (2011) C.-C. Wu et al. SCIENCE
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
- (2010) Yves Pommier et al. CHEMISTRY & BIOLOGY
- Strategies for discovering and derisking covalent, irreversible enzyme inhibitors
- (2010) Douglas S Johnson et al. Future Medicinal Chemistry
- The roles of drug metabolism in the pathogenesis of T-cell-mediated drug hypersensitivity
- (2009) Sidonie Nelly Lavergne et al. Current Opinion in Allergy and Clinical Immunology
- Covalent Modifiers: An Orthogonal Approach to Drug Design
- (2009) Michele H. Potashman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases
- (2009) Ivan Laponogov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Immune-Mediated Adverse Drug Reactions
- (2008) Jack Uetrecht CHEMICAL RESEARCH IN TOXICOLOGY
- Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage
- (2008) X. S. Pan et al. NUCLEIC ACIDS RESEARCH
- The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing
- (2008) J. E. Deweese et al. NUCLEIC ACIDS RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now