Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5

RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells

(2016) Vaclav Urban et al.   JOURNAL OF CELL BIOLOGY

Single nucleotide polymorphism in the RECQL5 gene increased osteosarcoma susceptibility in a Chinese Han population

(2015) Y.Z. Dong et al.   GENETICS AND MOLECULAR RESEARCH

Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

(2015) Joseph A. Newman et al.   NUCLEIC ACIDS RESEARCH

Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures

(2015) Ashley C. W. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases

(2015) Kelly A. Manthei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability

(2015) Edwin Chen et al.   Cell Reports

RECQL5 Controls Transcript Elongation and Suppresses Genome Instability Associated with Transcription Stress

(2014) Marco Saponaro et al.   CELL

RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway

(2014) Tae Moon Kim et al.   NUCLEIC ACIDS RESEARCH

Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations

(2014) Kata Sarlós et al.   NUCLEIC ACIDS RESEARCH

Association between RECQL5 genetic polymorphisms and susceptibility to breast cancer

(2014) Yu-Jun He et al.   TUMOR BIOLOGY

Crystal Structure ofDeinococcus radioduransRecQ Helicase Catalytic Core Domain: The Interdomain Flexibility

(2014) Sheng-Chia Chen et al.   Biomed Research International

Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA

(2014) Michael K. Swan et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Human RECQL5: Guarding the crossroads of DNA replication and transcription and providing backup capability

(2013) Venkateswarlu Popuri et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Accurate assessment of mass, models and resolution by small-angle scattering

(2013) Robert P. Rambo et al.   NATURE

Comprehensive macromolecular conformations mapped by quantitative SAXS analyses

(2013) Greg L Hura et al.   NATURE METHODS

Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5

(2013) Susanne A Kassube et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recruitment and retention dynamics of RECQL5 at DNA double strand break sites

(2012) Venkateswarlu Popuri et al.   DNA REPAIR

A Variant of the Breast Cancer Type 2 Susceptibility Protein (BRC) Repeat Is Essential for the RECQL5 Helicase to Interact with RAD51 Recombinase for Genome Stabilization

(2012) M. Nurul Islam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human RECQL5 participates in the removal of endogenous DNA damage

(2012) Takashi Tadokoro et al.   MOLECULAR BIOLOGY OF THE CELL

RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression

(2011) Mahesh Ramamoorthy et al.   NUCLEIC ACIDS RESEARCH

A Blm-Recql5 partnership in replication stress response

(2011) X. Lu et al.   Journal of Molecular Cell Biology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity

(2010) Sybille Schwendener et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA

(2010) Máté Gyimesi et al.   NUCLEIC ACIDS RESEARCH

Human RECQL5β stimulates flap endonuclease 1

(2010) Elżbieta Speina et al.   NUCLEIC ACIDS RESEARCH

RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

(2010) Radhakrishnan Kanagaraj et al.   NUCLEIC ACIDS RESEARCH

DAMMIF, a program for rapidab-initioshape determination in small-angle scattering

(2009) Daniel Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Direct Inhibition of RNA Polymerase II Transcription by RECQL5

(2009) Ozan Aygün et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MRE11 complex links RECQ5 helicase to sites of DNA damage

(2009) Lu Zheng et al.   NUCLEIC ACIDS RESEARCH

Structure of the human RECQ1 helicase reveals a putative strand-separation pin

(2009) A. C. W. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The zinc-binding motif of human RECQ5β suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme

(2008) Hua Ren et al.   BIOCHEMICAL JOURNAL

A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin

(2008) O. Aygun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA