RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway

Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses

(2014) M. Peng et al.   EMBO JOURNAL

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

(2014) Eeson Rajendra et al.   MOLECULAR CELL

Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks

(2014) Tae Moon Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Modularized Functions of the Fanconi Anemia Core Complex

(2014) Yaling Huang et al.   Cell Reports

Replication Stress-Induced Genome Instability: The Dark Side of Replication Maintenance by Homologous Recombination

(2013) Antony M. Carr et al.   JOURNAL OF MOLECULAR BIOLOGY

Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes

(2013) Lingchuan Hu et al.   NATURE

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

(2013) Matteo Berti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

(2013) Indrajit Chaudhury et al.   NUCLEIC ACIDS RESEARCH

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing

(2013) Shreya Paliwal et al.   NUCLEIC ACIDS RESEARCH

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

RAD51 Mutants Cause Replication Defects and Chromosomal Instability

(2012) T. M. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats

(2012) Ken’Ichi Mizuno et al.   NATURE

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase

(2012) Archana Sareen et al.   NUCLEIC ACIDS RESEARCH

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

Analysis of protein dynamics at active, stalled, and collapsed replication forks

(2011) B. M. Sirbu et al.   GENES & DEVELOPMENT

The phenotype of FancB-mutant mouse embryonic stem cells

(2011) Tae Moon Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts

(2011) Bénédicte Recolin et al.   NUCLEIC ACIDS RESEARCH

Rationale for the opposite stereochemistry of the major monoadducts and interstrand crosslinks formed by mitomycin C and its decarbamoylated analogue at CpG steps in DNA and the effect of cytosine modification on reactivity

(2011) Juan A. Bueren-Calabuig et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer

(2010) Philip S. Rudland et al.   AMERICAN JOURNAL OF PATHOLOGY

Cellular Strategies for Regulating DNA Supercoiling: A Single-Molecule Perspective

(2010) Daniel A. Koster et al.   CELL

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

(2010) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

(2010) P. Pace et al.   SCIENCE

DNA end resection: Many nucleases make light work

(2009) Eleni P. Mimitou et al.   DNA REPAIR

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

(2009) Mireille Tittel-Elmer et al.   EMBO JOURNAL

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

(2009) Helen E Bryant et al.   EMBO JOURNAL

Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism

(2009) K. Mizuno et al.   GENES & DEVELOPMENT

Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: Mechanistic insights

(2009) Larry H. Thompson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

(2008) R. Scott Williams et al.   CELL

Recql5 Plays an Important Role in DNA Replication and Cell Survival after Camptothecin Treatment

(2008) Yiduo Hu et al.   MOLECULAR BIOLOGY OF THE CELL