A Variant of the Breast Cancer Type 2 Susceptibility Protein (BRC) Repeat Is Essential for the RECQL5 Helicase to Interact with RAD51 Recombinase for Genome Stabilization

Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51

(2011) Kazuhiko Ochiai et al.   FEBS LETTERS

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

(2011) A. Carreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity

(2010) Sybille Schwendener et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RecQL5 Promotes Genome Stabilization through Two Parallel Mechanisms--Interacting with RNA Polymerase II and Acting as a Helicase

(2010) M. N. Islam et al.   MOLECULAR AND CELLULAR BIOLOGY

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA

(2010) Jie Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA

(2010) Tina Thorslund et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

(2009) Aura Carreira et al.   CELL

Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination

(2009) R. Prakash et al.   GENES & DEVELOPMENT

Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption

(2009) S. Colavito et al.   NUCLEIC ACIDS RESEARCH

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

(2009) Eeson Rajendra et al.   NUCLEIC ACIDS RESEARCH

QMEAN server for protein model quality estimation

(2009) Pascal Benkert et al.   NUCLEIC ACIDS RESEARCH

The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

(2009) M. K. K. Shivji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

(2008) Louise J. Barber et al.   CELL

Recql5 Plays an Important Role in DNA Replication and Cell Survival after Camptothecin Treatment

(2008) Yiduo Hu et al.   MOLECULAR BIOLOGY OF THE CELL