Human RECQL5: Guarding the crossroads of DNA replication and transcription and providing backup capability

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

RECQ1 plays a distinct role in cellular response to oxidative DNA damage

(2012) Sudha Sharma et al.   DNA REPAIR

Recruitment and retention dynamics of RECQL5 at DNA double strand break sites

(2012) Venkateswarlu Popuri et al.   DNA REPAIR

A Variant of the Breast Cancer Type 2 Susceptibility Protein (BRC) Repeat Is Essential for the RECQL5 Helicase to Interact with RAD51 Recombinase for Genome Stabilization

(2012) M. Nurul Islam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human RECQL5 participates in the removal of endogenous DNA damage

(2012) Takashi Tadokoro et al.   MOLECULAR BIOLOGY OF THE CELL

RECQL5 plays co-operative and complementary roles with WRN syndrome helicase

(2012) Venkateswarlu Popuri et al.   NUCLEIC ACIDS RESEARCH

RECQL5 is an important determinant for camptothecin tolerance in human colorectal cancer cells

(2011) Xiaoqi Wang et al.   BIOSCIENCE REPORTS

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells

(2011) Ruth E. Gonzalez et al.   CELL CYCLE

Anaphase DNA bridges induced by lack of RecQ5 inDrosophilasyncytial embryos

(2011) Haruna Sakurai et al.   FEBS LETTERS

WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes

(2011) B. S. Patro et al.   JOURNAL OF CELL SCIENCE

The Set2-RPB1 Interaction Domain of Human RECQ5 Is Important for Transcription-Associated Genome Stability

(2011) M. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

(2011) Anne Helmrich et al.   MOLECULAR CELL

RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression

(2011) Mahesh Ramamoorthy et al.   NUCLEIC ACIDS RESEARCH

A Blm-Recql5 partnership in replication stress response

(2011) X. Lu et al.   Journal of Molecular Cell Biology

The involvement of human RECQL4 in DNA double-strand break repair

(2010) Dharmendra Kumar Singh et al.   AGING CELL

Human RECQL5 overcomes thymidine-induced replication stress

(2010) Rachel Blundred et al.   DNA REPAIR

RECQL5 helicase: Connections to DNA recombination and RNA polymerase II transcription

(2010) Ozan Aygün et al.   DNA REPAIR

The association of telomere length and genetic variation in telomere biology genesa

(2010) Lisa Mirabello et al.   HUMAN MUTATION

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity

(2010) Sybille Schwendener et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RecQL5 Promotes Genome Stabilization through Two Parallel Mechanisms--Interacting with RNA Polymerase II and Acting as a Helicase

(2010) M. N. Islam et al.   MOLECULAR AND CELLULAR BIOLOGY

Human RECQL5β stimulates flap endonuclease 1

(2010) Elżbieta Speina et al.   NUCLEIC ACIDS RESEARCH

RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

(2010) Radhakrishnan Kanagaraj et al.   NUCLEIC ACIDS RESEARCH

RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination

(2010) E.-J. Uringa et al.   NUCLEIC ACIDS RESEARCH

Topoisomerase IIα maintains genomic stability through decatenation G2 checkpoint signaling

(2010) J J Bower et al.   ONCOGENE

RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis

(2010) J. L. Youds et al.   SCIENCE

Effect of Recql5 deficiency on the intestinal tumor susceptibility ofApcminmice

(2010) Yiduo Hu   WORLD JOURNAL OF GASTROENTEROLOGY

Drosophila RecQ5 is required for efficient SSA repair and suppression of LOH in vivo

(2010) Yixu Chen et al.   Protein & Cell

The role of recombination in telomere length maintenance

(2009) Nicola J. Royle et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Establishment of Sister Chromatid Cohesion

(2009) Robert V. Skibbens   CURRENT BIOLOGY

Direct and indirect roles of RECQL4 in modulating base excision repair capacity

(2009) Shepherd H. Schurman et al.   HUMAN MOLECULAR GENETICS

Bloom Syndrome Helicase Stimulates RAD51 DNA Strand Exchange Activity through a Novel Mechanism

(2009) Dmitry V. Bugreev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomeric D-loops Containing 8-Oxo-2′-deoxyguanosine Are Preferred Substrates for Werner and Bloom Syndrome Helicases and Are Bound by POT1

(2009) Avik Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Inhibition of RNA Polymerase II Transcription by RECQL5

(2009) Ozan Aygün et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo

(2009) Rebecca C. Burgess et al.   JOURNAL OF CELL BIOLOGY

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

Transcription-associated recombination in eukaryotes: link between transcription, replication and recombination

(2009) P. Gottipati et al.   MUTAGENESIS

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

(2009) Sandie Tuduri et al.   NATURE CELL BIOLOGY

MRE11 complex links RECQ5 helicase to sites of DNA damage

(2009) Lu Zheng et al.   NUCLEIC ACIDS RESEARCH

Structure of the human RECQ1 helicase reveals a putative strand-separation pin

(2009) A. C. W. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity

(2008) Robert D. C. Saunders et al.   AGING CELL

The zinc-binding motif of human RECQ5β suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme

(2008) Hua Ren et al.   BIOCHEMICAL JOURNAL

Association of human DNA helicase RecQ5β with RNA polymerase II and its possible role in transcription

(2008) Keiichi Izumikawa et al.   BIOCHEMICAL JOURNAL

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

(2008) Louise J. Barber et al.   CELL

Loss of RecQ5 leads to spontaneous mitotic defects and chromosomal aberrations in Drosophila melanogaster

(2008) Minoru Nakayama et al.   DNA REPAIR

Werner syndrome helicase activity is essential in maintaining fragile site stability

(2008) Livia Maria Pirzio et al.   JOURNAL OF CELL BIOLOGY

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

(2008) Annapaola Franchitto et al.   JOURNAL OF CELL BIOLOGY

WRN Is Required for ATM Activation and the S-Phase Checkpoint in Response to Interstrand Cross-Link–Induced DNA Double-Strand Breaks

(2008) Wen-Hsing Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of the DNA Damage Checkpoint in Mutants Defective in DNA Replication Initiation

(2008) Ling Yin et al.   MOLECULAR BIOLOGY OF THE CELL

Recql5 Plays an Important Role in DNA Replication and Cell Survival after Camptothecin Treatment

(2008) Yiduo Hu et al.   MOLECULAR BIOLOGY OF THE CELL

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin

(2008) O. Aygun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance

(2008) V BOHR   TRENDS IN BIOCHEMICAL SCIENCES