Transforming growth factor-β and stem cell markers are highly expressed around necrotic areas in glioblastoma

Glioblastoma: pathology, molecular mechanisms and markers

(2015) Kenneth Aldape et al.   ACTA NEUROPATHOLOGICA

A radiosensitivity gene signature in predicting glioma prognostic via EMT pathway

(2015) Jin Meng et al.   Oncotarget

Radiation promotes malignant progression of glioma cells through HIF-1alpha stabilization

(2014) Young-Heon Kim et al.   CANCER LETTERS

Genome-Wide Analysis in Human Colorectal Cancer Cells Reveals Ischemia-Mediated Expression of Motility Genes via DNA Hypomethylation

(2014) Karolina Skowronki et al.   PLoS One

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

TGF-  Mediates Homing of Bone Marrow-Derived Human Mesenchymal Stem Cells to Glioma Stem Cells

(2013) N. Shinojima et al.   CANCER RESEARCH

Targeting Role of Glioma Stem Cells for Gliobastoma Multiforme

(2013) X. Zhang et al.   CURRENT MEDICINAL CHEMISTRY

Brain tumor stem cells: Molecular characteristics and their impact on therapy

(2013) David L. Schonberg et al.   MOLECULAR ASPECTS OF MEDICINE

Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma

(2013) Roshan Mahabir et al.   NEURO-ONCOLOGY

Investigating the Link between Molecular Subtypes of Glioblastoma, Epithelial-Mesenchymal Transition, and CD133 Cell Surface Protein

(2013) Hadi Zarkoob et al.   PLoS One

Recruited Brain Tumor-Derived Mesenchymal Stem Cells Contribute to Brain Tumor Progression

(2013) Jinan Behnan et al.   STEM CELLS

The Tumor Microenvironment Strongly Impacts Master Transcriptional Regulators and Gene Expression Class of Glioblastoma

(2012) Lee A.D. Cooper et al.   AMERICAN JOURNAL OF PATHOLOGY

Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas

(2012) U.D. Kahlert et al.   CANCER LETTERS

Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β

(2012) Matthew E. Hardee et al.   CANCER RESEARCH

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype

(2012) Y. Piao et al.   NEURO-ONCOLOGY

Blockade of TGF-  Signaling by the TGF R-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma

(2011) M. Zhang et al.   CANCER RESEARCH

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

Ionizing Radiation Promotes Migration and Invasion of Cancer Cells Through Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition

(2011) Yong-Chun Zhou et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells

(2011) Jan Theys et al.   RADIOTHERAPY AND ONCOLOGY

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

TWIST1 promotes invasion through mesenchymal change in human glioblastoma

(2010) Svetlana A Mikheeva et al.   Molecular Cancer

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target

(2009) Randy L. Jensen   JOURNAL OF NEURO-ONCOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Combination of Vascular Endothelial Growth Factor Receptor/Platelet-Derived Growth Factor Receptor Inhibition Markedly Improves Radiation Tumor Therapy

(2008) C. Timke et al.   CLINICAL CANCER RESEARCH

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY