The Role of the Gut Microbiome in Multiple Sclerosis Risk and Progression: Towards Characterization of the “MS Microbiome”

Influence of the Gut Microbiome on Autoimmunity in the Central Nervous System

(2017) Sara L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

The role of peripheral immune cells in the CNS in steady state and disease

(2017) Marco Prinz et al.   NATURE NEUROSCIENCE

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

(2017) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

(2017) Xavier Montalban et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice

(2017) Kerstin Berer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgA-coatedE. colienriched in Crohn’s disease spondyloarthritis promote TH17-dependent inflammation

(2017) Monica Viladomiu et al.   Science Translational Medicine

Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers

(2017) Hartmut Wekerle   TRENDS IN IMMUNOLOGY

The Human Microbiome and the Missing Heritability Problem

(2017) Santiago Sandoval-Motta et al.   Frontiers in Genetics

Gut microbiome analysis in neuromyelitis optica reveals overabundance ofClostridium perfringens

(2016) Bruce A. C. Cree et al.   ANNALS OF NEUROLOGY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Environmental factors and their interactions with risk genotypes in MS susceptibility

(2016) A.K. Hedström et al.   CURRENT OPINION IN NEUROLOGY

An integrated metagenomics pipeline for strain profiling reveals novel patterns of bacterial transmission and biogeography

(2016) Stephen Nayfach et al.   GENOME RESEARCH

Gut microbiota composition and relapse risk in pediatric MS: A pilot study

(2016) Helen Tremlett et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study

(2016) Maria Chiara Buscarinu et al.   Multiple Sclerosis Journal

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis

(2016) Tomas Olsson et al.   Nature Reviews Neurology

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

(2016) Mar Gacias et al.   eLife

Altered intestinal permeability in patients with relapsing–remitting multiple sclerosis: A pilot study

(2016) Maria Chiara Buscarinu et al.   Multiple Sclerosis Journal

High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice

(2016) Shinsaku Okai et al.   Nature Microbiology

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

(2016) Jun Chen et al.   Scientific Reports

Gut Microbiota in Multiple Sclerosis

(2015) Brandi L. Cantarel et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Smoking is a major preventable risk factor for multiple sclerosis

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Role of astrocytes and microglia in central nervous system inflammation

(2015) Veit Rothhammer et al.   Seminars in Immunopathology

Smoking is a major preventable risk factor for multiple sclerosis

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease

(2014) Noah W. Palm et al.   CELL

The Charcot Lecture | Beating MS: A story of B cells, with twists and turns

(2014) Stephen L Hauser   Multiple Sclerosis Journal

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production

(2014) Elizabeth C Rosser et al.   NATURE MEDICINE

Printing soil: a single-step, high-throughput method to isolate micro-organisms and near-neighbour microbial consortia from a complex environmental sample

(2014) Bradley R. Ringeisen et al.   Methods in Ecology and Evolution

Anti-Gal: an abundant human natural antibody of multiple pathogeneses and clinical benefits

(2013) Uri Galili   IMMUNOLOGY

Cytomegalovirus seropositivity is negatively associated with multiple sclerosis

(2013) E Sundqvist et al.   Multiple Sclerosis Journal

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

(2013) Koji Atarashi et al.   NATURE

Microbial colonization influences early B-lineage development in the gut lamina propria

(2013) Duane R. Wesemann et al.   NATURE

Anti-cancer therapies affected by gut microbiota

(2013) Claire Greenhill   Nature Reviews Gastroenterology & Hepatology

Commensal Akkermansia muciniphila Exacerbates Gut Inflammation in Salmonella Typhimurium-Infected Gnotobiotic Mice

(2013) Bhanu Priya Ganesh et al.   PLoS One

Isolation of Clostridium perfringens Type B in an Individual at First Clinical Presentation of Multiple Sclerosis Provides Clues for Environmental Triggers of the Disease

(2013) Kareem Rashid Rumah et al.   PLoS One

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

(2013) M. I. Smith et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

The Human Microbiome: Our Second Genome

(2012) Elizabeth A. Grice et al.   Annual Review of Genomics and Human Genetics

Voices from within: gut microbes and the CNS

(2012) Paul Forsythe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

B cells and antibodies in multiple sclerosis pathogenesis and therapy

(2012) Markus Krumbholz et al.   Nature Reviews Neurology

Intestinal microbiota in human health and disease: the impact of probiotics

(2011) Jacoline Gerritsen et al.   Genes and Nutrition

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Experimental and analytical tools for studying the human microbiome

(2011) Justin Kuczynski et al.   NATURE REVIEWS GENETICS

Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

(2011) Dag Henrik Reikvam et al.   PLoS One

Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice

(2011) A. L. Goodman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting a Human Gut Microbiota's Response to Diet in Gnotobiotic Mice

(2011) J. J. Faith et al.   SCIENCE

The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins

(2011) N. P. McNulty et al.   Science Translational Medicine

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE