Genetic Approaches to Understanding Psychiatric Disease

The Familial Co-Aggregation of Attention-Deficit/Hyperactivity Disorder and Intellectual Disability: A Register-Based Family Study

(2017) Stephen V. Faraone et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

The familial co-aggregation of ASD and ADHD: a register-based cohort study

(2017) L Ghirardi et al.   MOLECULAR PSYCHIATRY

Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders

(2017) Ileena Mitra et al.   PLoS Genetics

Diagnostic Yield and Novel Candidate Genes by Exome Sequencing in 152 Consanguineous Families With Neurodevelopmental Disorders

(2017) Miriam S. Reuter et al.   JAMA Psychiatry

Glutamatergic and GABAergic gene sets in attention-deficit/hyperactivity disorder: association to overlapping traits in ADHD and autism

(2017) J Naaijen et al.   Translational Psychiatry

Gene—Environment Interactions in Major Depressive Disorder

(2017) Torsten Klengel et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

Mutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia

(2016) Elizabeth J. Bhoj et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA

(2016) Tychele N. Turner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders

(2016) Holly A.F. Stessman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy

(2016) Robert Kopajtich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules

(2016) Korinna Kochinke et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility

(2016) Ariel F. Martinez et al.   BIOLOGICAL PSYCHIATRY

Genetics of attention-deficit/hyperactivity disorder: an update

(2016) Glaucia Chiyoko Akutagava-Martins et al.   Expert Review of Neurotherapeutics

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

(2016) Liping Hou et al.   HUMAN MOLECULAR GENETICS

Annual Research Review: The role of the environment in the developmental psychopathology of autism spectrum condition

(2016) William Mandy et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Prevalence and Characteristics of Autism Spectrum Disorder Among 4-Year-Old Children in the Autism and Developmental Disabilities Monitoring Network

(2016) Deborah L. Christensen et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder

(2016) Mohamed Abdulkadir et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Whole-Exome Sequencing Reveals Increased Burden of Rare Functional and Disruptive Variants in Candidate Risk Genes in Individuals With Persistent Attention-Deficit/Hyperactivity Disorder

(2016) Ditte Demontis et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions

(2016) N Kappelmann et al.   MOLECULAR PSYCHIATRY

From genetics to physiology at last

(2016) Ryan S. Dhindsa et al.   NATURE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Haplotyping germline and cancer genomes with high-throughput linked-read sequencing

(2016) Grace X Y Zheng et al.   NATURE BIOTECHNOLOGY

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

(2016) Elise B Robinson et al.   NATURE GENETICS

Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability

(2016) Stefan H Lelieveld et al.   NATURE NEUROSCIENCE

Down syndrome and the complexity of genome dosage imbalance

(2016) Stylianos E. Antonarakis   NATURE REVIEWS GENETICS

Coming of age: ten years of next-generation sequencing technologies

(2016) Sara Goodwin et al.   NATURE REVIEWS GENETICS

Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2

(2016) Ellen J. Hoffman et al.   NEURON

Genome-Wide Association and Exome Sequencing Study of Language Disorder in an Isolated Population

(2016) S. A. Kornilov et al.   PEDIATRICS

Animal models of gene–environment interaction in schizophrenia: A dimensional perspective

(2016) Yavuz Ayhan et al.   PROGRESS IN NEUROBIOLOGY

A global genetic interaction network maps a wiring diagram of cellular function

(2016) M. Costanzo et al.   SCIENCE

Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials

(2016) Elizabeth Berry-Kravis et al.   Science Translational Medicine

Molecular Inversion Probes for targeted resequencing in non-model organisms

(2016) M. Niedzicka et al.   Scientific Reports

Genetics of attention-deficit/hyperactivity disorder: an update

(2016) Glaucia Chiyoko Akutagava-Martins et al.   Expert Review of Neurotherapeutics

Exome Sequencing of Familial Bipolar Disorder

(2016) Fernando S. Goes et al.   JAMA Psychiatry

Exome chip analyses in adult attention deficit hyperactivity disorder

(2016) T Zayats et al.   Translational Psychiatry

Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort

(2016) Shanmukha S. Padmanabhuni et al.   Frontiers in Neuroscience

SLINGER: large-scale learning for predicting gene expression

(2016) Kévin Vervier et al.   Scientific Reports

De Novo Mutations in CHAMP1 Cause Intellectual Disability with Severe Speech Impairment

(2015) Maja Hempel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Risk for Schizophrenia: Convergence on Synaptic Pathways Involved in Plasticity

(2015) Jeremy Hall et al.   BIOLOGICAL PSYCHIATRY

Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation

(2015) Benjamin M Neale et al.   CURRENT OPINION IN NEUROBIOLOGY

Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A

(2015) Lucas M Bronicki et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome-wide analysis identifies a role for common copy number variants in specific language impairment

(2015) Nuala H Simpson et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Association of LPHN3 rs6551665 A/G polymorphism with attention deficit and hyperactivity disorder in Korean children

(2015) In Wook Hwang et al.   GENE

LPHN3 and attention-deficit/hyperactivity disorder: a susceptibility and pharmacogenetic study

(2015) E. M. Bruxel et al.   GENES BRAIN AND BEHAVIOR

Epigenetics of Autism-related Impairment

(2015) Varvara Mazina et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Gene expression in major depressive disorder

(2015) R Jansen et al.   MOLECULAR PSYCHIATRY

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

(2015) T-K Clarke et al.   MOLECULAR PSYCHIATRY

The molecular genetic architecture of attention deficit hyperactivity disorder

(2015) Z Hawi et al.   MOLECULAR PSYCHIATRY

Sparse whole-genome sequencing identifies two loci for major depressive disorder

(2015) Na Cai et al.   NATURE

Excess of rare, inherited truncating mutations in autism

(2015) Niklas Krumm et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion

(2015) Di Tian et al.   NATURE NEUROSCIENCE

Polygenic risk scores for schizophrenia and bipolar disorder predict creativity

(2015) Robert A Power et al.   NATURE NEUROSCIENCE

The Genetics of Stress-Related Disorders: PTSD, Depression and Anxiety Disorders

(2015) Jordan W Smoller   NEUROPSYCHOPHARMACOLOGY

Discontinuity in the genetic and environmental causes of the intellectual disability spectrum

(2015) Abraham Reichenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion

(2015) Yue C. Lu et al.   STRUCTURE

Epigenome-Wide Association Study of Tic Disorders

(2015) Nuno R. Zilhão et al.   Twin Research and Human Genetics

Involvement of NRN1 gene in schizophrenia-spectrum and bipolar disorders and its impact on age at onset and cognitive functioning

(2015) Mar Fatjó-Vilas et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Exome Sequencing in an Admixed Isolated Population Indicates NFXL1 Variants Confer a Risk for Specific Language Impairment

(2015) Pía Villanueva et al.   PLoS Genetics

Lifetime Prevalence, Age of Risk, and Genetic Relationships of Comorbid Psychiatric Disorders in Tourette Syndrome

(2015) Matthew E. Hirschtritt et al.   JAMA Psychiatry

The female protective effect in autism spectrum disorder is not mediated by a single genetic locus

(2015) Jake Gockley et al.   Molecular Autism

Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins

(2015) Donna M Werling et al.   Molecular Autism

PacBio Sequencing and Its Applications

(2015) Anthony Rhoads et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Transcriptional Consequences of 16p11.2 Deletion and Duplication in Mouse Cortex and Multiplex Autism Families

(2014) Ian Blumenthal et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Higher Mutational Burden in Females Supports a “Female Protective Model” in Neurodevelopmental Disorders

(2014) Sébastien Jacquemont et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Glutamatergic copy number variants and their role in attention-deficit/hyperactivity disorder

(2014) Glaucia Chiyoko Akutagava-Martins et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genetic association signal nearNTN4in Tourette syndrome

(2014) Peristera Paschou et al.   ANNALS OF NEUROLOGY

Methylphenidate Exerts Dose-Dependent Effects on Glutamate Receptors and Behaviors

(2014) Jia Cheng et al.   BIOLOGICAL PSYCHIATRY

A Genotype-First Approach to Defining the Subtypes of a Complex Disease

(2014) Holly A. Stessman et al.   CELL

Analysis of genetic association and epistasis interactions between circadian clock genes and symptom dimensions of bipolar affective disorder

(2014) Malgorzata Maciukiewicz et al.   CHRONOBIOLOGY INTERNATIONAL

Association of SNAP-25, SLC6A2, and LPHN3 With OROS Methylphenidate Treatment Response in Attention-Deficit/Hyperactivity Disorder

(2014) Jungeun Song et al.   CLINICAL NEUROPHARMACOLOGY

The Akt-mTOR Pathway in Down’s Syndrome: The Potential Use of Rapamycin/Rapalogs for Treating Cognitive Deficits

(2014) Jose Troca-Marin et al.   CNS & Neurological Disorders-Drug Targets

The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods

(2014) Andrea Dietrich et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Genome-wide screening for DNA variants associated with reading and language traits

(2014) A. Gialluisi et al.   GENES BRAIN AND BEHAVIOR

New microdeletion and microduplication syndromes: a comprehensive review

(2014) Julián Nevado et al.   GENETICS AND MOLECULAR BIOLOGY

Summarizing polygenic risks for complex diseases in a clinical whole-genome report

(2014) Sek Won Kong et al.   GENETICS IN MEDICINE

Branched-chain amino acid metabolism: from rare Mendelian diseases to more common disorders

(2014) L. C. Burrage et al.   HUMAN MOLECULAR GENETICS

The Familial Risk of Autism

(2014) Sven Sandin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Metabotropic Glutamate Receptor Subtype 7 rs3792452 Polymorphism Is Associated with the Response to Methylphenidate in Children with Attention-Deficit/Hyperactivity Disorder

(2014) Subin Park et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

X-linked creatine transporter deficiency: clinical aspects and pathophysiology

(2014) Jiddeke M. van de Kamp et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Congenital disorders of glycosylation: new defects and still counting

(2014) Kyle Scott et al.   JOURNAL OF INHERITED METABOLIC DISEASE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Genome sequencing identifies major causes of severe intellectual disability

(2014) Christian Gilissen et al.   NATURE

Resolving the complexity of the human genome using single-molecule sequencing

(2014) Mark J. P. Chaisson et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP

(2014) Céline Helsmoortel et al.   NATURE GENETICS

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Most genetic risk for autism resides with common variation

(2014) Trent Gaugler et al.   NATURE GENETICS

One gene, many neuropsychiatric disorders: lessons from Mendelian diseases

(2014) Xiaolin Zhu et al.   NATURE NEUROSCIENCE

LPHN3, a presynaptic adhesion-GPCR implicated in ADHD, regulates the strength of neocortical layer 2/3 synaptic input to layer 5

(2014) Matthew L O’Sullivan et al.   Neural Development

The Genetics of Major Depression

(2014) Jonathan Flint et al.   NEURON

Histidine Decarboxylase Deficiency Causes Tourette Syndrome: Parallel Findings in Humans and Mice

(2014) Lissandra Castellan Baldan et al.   NEURON

Long-Term Memory Deficits are Associated with Elevated Synaptic ERK1/2 Activation and Reversed by mGluR5 Antagonism in an Animal Model of Autism

(2014) Ronald R Seese et al.   NEUROPSYCHOPHARMACOLOGY

Molecular genetic studies of ADHD and its candidate genes: A review

(2014) Zhao Li et al.   PSYCHIATRY RESEARCH

Identifying Gene-Environment Interactions in Schizophrenia: Contemporary Challenges for Integrated, Large-scale Investigations

(2014)   SCHIZOPHRENIA BULLETIN

The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism

(2014) Dexter Hadley et al.   Nature Communications

De novo TBR1 mutations in sporadic autism disrupt protein functions

(2014) Pelagia Deriziotis et al.   Nature Communications

Variability in Working Memory Performance Explained by Epistasis vs Polygenic Scores in theZNF804APathway

(2014) Kristin K. Nicodemus et al.   JAMA Psychiatry

DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics

(2014) Li Liu et al.   Molecular Autism

Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding

(2014) B H Schott et al.   Translational Psychiatry

Glutamate/glutamine and neuronal integrity in adults with ADHD: a proton MRS study

(2014) S Maltezos et al.   Translational Psychiatry

Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing

(2013) Yong-hui Jiang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

New innovations: Therapeutic opportunities for intellectual disabilities

(2013) Jonathan D. Picker et al.   ANNALS OF NEUROLOGY

Sex differences in autism spectrum disorders

(2013) Donna M. Werling et al.   CURRENT OPINION IN NEUROLOGY

Molecular basis for prospective pharmacological treatment strategies in intellectual disability syndromes

(2013) Chiara Verpelli et al.   Developmental Neurobiology

The emerging role ofSHANKgenes in neuropsychiatric disorders

(2013) Audrey Guilmatre et al.   Developmental Neurobiology

Contactins in the neurobiology of autism

(2013) Amila Zuko et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder

(2013) Alberto Chiesa et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Support of the histaminergic hypothesis in Tourette Syndrome: association of the histamine decarboxylase gene in a large sample of families

(2013) Iordanis Karagiannidis et al.   JOURNAL OF MEDICAL GENETICS

Candidate Genetic Pathways for Attention-Deficit/Hyperactivity Disorder (ADHD) Show Association to Hyperactive/Impulsive Symptoms in Children With ADHD

(2013) Janita Bralten et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Translating dosage compensation to trisomy 21

(2013) Jun Jiang et al.   NATURE

A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

(2013) Christie M Buchovecky et al.   NATURE GENETICS

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

Epistatic interaction between CRHR1 and AVPR1b variants as a predictor of major depressive disorder

(2013) Aleksandra Szczepankiewicz et al.   PSYCHIATRIC GENETICS

Huntington's disease: underlying molecular mechanisms and emerging concepts

(2013) John Labbadia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Neurexins

(2013) Carsten Reissner et al.   GENOME BIOLOGY

Comorbidities and Mortality in Bipolar Disorder

(2013) Casey Crump et al.   JAMA Psychiatry

Refining psychiatric phenotypes for response to treatment: Contribution of LPHN3 in ADHD

(2012) Aurelie Labbe et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice

(2012) Ilse Gantois et al.   BEHAVIOURAL BRAIN RESEARCH

CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics

(2012) Dheeraj Malhotra et al.   CELL

Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation

(2012) Jacob J. Michaelson et al.   CELL

The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses

(2012) Dilja D Krueger et al.   CURRENT OPINION IN NEUROBIOLOGY

Influence of a Latrophilin 3 (LPHN3) risk haplotype on event-related potential measures of cognitive response control in attention-deficit hyperactivity disorder (ADHD)

(2012) Andreas J. Fallgatter et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Dances with black widow spiders: Dysregulation of glutamate signalling enters centre stage in ADHD

(2012) K.P. Lesch et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A common genetic network underlies substance use disorders and disruptive or externalizing disorders

(2012) Mauricio Arcos-Burgos et al.   HUMAN GENETICS

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction

(2012) Frances M. Platt et al.   JOURNAL OF CELL BIOLOGY

LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancy

(2012) Zia Choudhry et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Treatable inborn errors of metabolism causing intellectual disability: A systematic literature review

(2012) Clara D.M. van Karnebeek et al.   MOLECULAR GENETICS AND METABOLISM

Genome-wide association study of Tourette's syndrome

(2012) J M Scharf et al.   MOLECULAR PSYCHIATRY

A mega-analysis of genome-wide association studies for major depressive disorder

(2012)   MOLECULAR PSYCHIATRY

KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

(2012) Christelle Golzio et al.   NATURE

Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

(2012) Sung Han et al.   NATURE

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

forestSV: structural variant discovery through statistical learning

(2012) Jacob J Michaelson et al.   NATURE METHODS

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

FLRT Proteins Are Endogenous Latrophilin Ligands and Regulate Excitatory Synapse Development

(2012) Matthew L. O'Sullivan et al.   NEURON

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

The Prevalence of DSM-IV Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review

(2012) Erik G. Willcutt   Neurotherapeutics

Deregulated mTOR-mediated translation in intellectual disability

(2012) José Antonio Troca-Marín et al.   PROGRESS IN NEUROBIOLOGY

Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant

(2012) Andreea S. Pop et al.   PSYCHOPHARMACOLOGY

Mutations in BCKD-kinase Lead to a Potentially Treatable Form of Autism with Epilepsy

(2012) G. Novarino et al.   SCIENCE

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

Integrated Genome-Wide Association Study Findings: Identification of a Neurodevelopmental Network for Attention Deficit Hyperactivity Disorder

(2011) Geert Poelmans et al.   AMERICAN JOURNAL OF PSYCHIATRY

Rare Copy Number Variants in Tourette Syndrome Disrupt Genes in Histaminergic Pathways and Overlap with Autism

(2011) Thomas V. Fernandez et al.   BIOLOGICAL PSYCHIATRY

Molecular basis of maternal age-related increase in oocyte aneuploidy

(2011) Hiroki Kurahashi et al.   CONGENITAL ANOMALIES

The genetics of Tourette disorder

(2011) Matthew W State   CURRENT OPINION IN GENETICS & DEVELOPMENT

Sexual differentiation of the human brain: Relation to gender identity, sexual orientation and neuropsychiatric disorders

(2011) Ai-Min Bao et al.   FRONTIERS IN NEUROENDOCRINOLOGY

A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD

(2011) M Jain et al.   MOLECULAR PSYCHIATRY

The genetics of attention deficit/hyperactivity disorder in adults, a review

(2011) B Franke et al.   MOLECULAR PSYCHIATRY

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

(2011) Sébastien Jacquemont et al.   NATURE

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

(2011) Josephine Elia et al.   NATURE GENETICS

Genome structural variation discovery and genotyping

(2011) Can Alkan et al.   NATURE REVIEWS GENETICS

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD

(2011) A. C. Lionel et al.   Science Translational Medicine

Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

(2011) S. Jacquemont et al.   Science Translational Medicine

A two-locus genetic interaction between LPHN3 and 11q predicts ADHD severity and long-term outcome

(2011) M T Acosta et al.   Translational Psychiatry

GENETIC BASIS OF SPECIFIC LANGUAGE IMPAIRMENT: EVIDENCE FROM A TWIN STUDY

(2010) D. V. M. Bishop et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Contribution of LPHN3 to the genetic susceptibility to ADHD in adulthood: a replication study

(2010) M. Ribasés et al.   GENES BRAIN AND BEHAVIOR

De novo rates and selection of large copy number variation

(2010) A. Itsara et al.   GENOME RESEARCH

Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis

(2010) Nigel M Williams et al.   LANCET

A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

(2010) M Arcos-Burgos et al.   MOLECULAR PSYCHIATRY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

L-Histidine Decarboxylase and Tourette's Syndrome

(2010) A. Gulhan Ercan-Sencicek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Accurately Assessing the Risk of Schizophrenia Conferred by Rare Copy-Number Variation Affecting Genes with Brain Function

(2010) Soumya Raychaudhuri et al.   PLoS Genetics

Copy Number Variation in Human Health, Disease, and Evolution

(2009) Feng Zhang et al.   Annual Review of Genomics and Human Genetics

Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis

(2009) Viktória Simon et al.   BRITISH JOURNAL OF PSYCHIATRY

Common statistical issues in genome-wide association studies: a review on power, data quality control, genotype calling and population structure

(2009) Yik Y Teo   CURRENT OPINION IN LIPIDOLOGY

A syndrome of short stature, microcephaly and speech delay is associated with duplications reciprocal to the common Sotos syndrome deletion

(2009) Luis M Franco et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes

(2009) J Elia et al.   MOLECULAR PSYCHIATRY

The genetics of bipolar disorder

(2009) J.H. Barnett et al.   NEUROSCIENCE

Comparative genomics of autism and schizophrenia

(2009) B. Crespi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rethinking environmental contributions to child and adolescent psychopathology: A meta-analysis of shared environmental influences.

(2009) S. Alexandra Burt   PSYCHOLOGICAL BULLETIN

Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders

(2009) Jonathan Sebat et al.   TRENDS IN GENETICS

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Intellectual disability co-occurring with schizophrenia and other psychiatric illness: population-based study

(2008) Vera A. Morgan et al.   BRITISH JOURNAL OF PSYCHIATRY

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies

(2008) Klaus-Peter Lesch et al.   JOURNAL OF NEURAL TRANSMISSION

Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities

(2008) Nicola Brunetti-Pierri et al.   NATURE GENETICS

Association between Microdeletion and Microduplication at 16p11.2 and Autism

(2008) Lauren A. Weiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Psychiatric Comorbidities and Schizophrenia

(2008) P. F. Buckley et al.   SCHIZOPHRENIA BULLETIN

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE