A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

(2013) Matthew J Lyst et al.   NATURE NEUROSCIENCE

Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome

(2013) Emily K. Osterweil et al.   NEURON

Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases

(2012) J. E. Vance   Disease Models & Mechanisms

A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma

(2012) Jeffrey G. McDonald et al.   JOURNAL OF LIPID RESEARCH

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

Rett Syndrome

(2011) Alan K. Percy   ARCHIVES OF NEUROLOGY

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

(2011) Saloni Gill et al.   Cell Metabolism

Synaptic microcircuit dysfunction in genetic models of neurodevelopmental disorders: focus on Mecp2 and Met

(2011) Gordon MG Shepherd et al.   CURRENT OPINION IN NEUROBIOLOGY

Therapeutics for Childhood Neurofibromatosis Type 1 and Type 2

(2011) Simone L. Ardern-Holmes et al.   Current Treatment Options in Neurology

Technical approaches for mouse models of human disease

(2011) M. J. Justice et al.   Disease Models & Mechanisms

Mouse Knockout of the Cholesterogenic Cytochrome P450 Lanosterol 14α-Demethylase (Cyp51) Resembles Antley-Bixler Syndrome

(2011) Rok Keber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Statins and their influence on brain cholesterol

(2011) L'ubica Cibičková   Journal of Clinical Lipidology

Diet-induced elevations in serum cholesterol are associated with alterations in hippocampal lipid metabolism and increased oxidative stress

(2011) Alexis M. Stranahan et al.   JOURNAL OF NEUROCHEMISTRY

Role of MeCP2, DNA methylation, and HDACs in regulating synapse function

(2011) Ege T. Kavalali et al.   Journal of Neurodevelopmental Disorders

A role for glia in the progression of Rett’s syndrome

(2011) Daniel T. Lioy et al.   NATURE

Mechanisms and functions of Hedgehog signalling across the metazoa

(2011) Philip W. Ingham et al.   NATURE REVIEWS GENETICS

Cholesterol metabolism in neurons and astrocytes

(2011) Frank W. Pfrieger et al.   PROGRESS IN LIPID RESEARCH

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Mutation discovery in mice by whole exome sequencing

(2011) Heather Fairfield et al.   GENOME BIOLOGY

Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge

(2010) Ingemar Björkhem et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain

(2009) David W. Russell et al.   Annual Review of Biochemistry

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Central nervous system: cholesterol turnover, brain development and neurodegeneration

(2009) John M. Dietschy   BIOLOGICAL CHEMISTRY

Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats

(2009) Katja Nieweg et al.   JOURNAL OF NEUROCHEMISTRY

Identification of the Arabidopsisdry2/sqe1-5mutant reveals a central role for sterols in drought tolerance and regulation of reactive oxygen species

(2009) David Posé et al.   PLANT JOURNAL

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

(2008) Sarah K Knutson et al.   EMBO JOURNAL

A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy

(2008) Ivana Matera et al.   HUMAN MOLECULAR GENETICS

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Deletion of Mecp2 in Sim1-Expressing Neurons Reveals a Critical Role for MeCP2 in Feeding Behavior, Aggression, and the Response to Stress

(2008) Sharyl L. Fyffe et al.   NEURON

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE